| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the urapidil-3078 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ACVR1B | activin A receptor, type IB |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AHSP | alpha hemoglobin stabilizing protein |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ASTN2 | astrotactin 2 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CD1E | CD1e molecule |
| CD247 | CD247 molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDHR1 | cadherin-related family member 1 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| COPE | coatomer protein complex, subunit epsilon |
| CTSZ | cathepsin Z |
| DCT | dopachrome tautomerase |
| DICER1 | dicer 1, ribonuclease type III |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DOK3 | docking protein 3 |
| DSCAM | Down syndrome cell adhesion molecule |
| EEA1 | early endosome antigen 1 |
| EHD1 | EH-domain containing 1 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EPS8L3 | EPS8-like 3 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FBXO40 | F-box protein 40 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF4 | fibroblast growth factor 4 |
| FOSL2 | FOS-like antigen 2 |
| FST | follistatin |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPATCH4 | G patch domain containing 4 |
| GPM6B | glycoprotein M6B |
| GPR15 | G protein-coupled receptor 15 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HKDC1 | hexokinase domain containing 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDS | iduronate 2-sulfatase |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLHL3 | kelch-like family member 3 |
| LAMB4 | laminin, beta 4 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MLXIPL | MLX interacting protein-like |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MTCL1 | microtubule crosslinking factor 1 |
| NEBL | nebulette |
| OSBPL10 | oxysterol binding protein-like 10 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PEX10 | peroxisomal biogenesis factor 10 |
| PLSCR3 | phospholipid scramblase 3 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| RASAL2 | RAS protein activator like 2 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| S100A1 | S100 calcium binding protein A1 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SERHL2 | serine hydrolase-like 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIX3 | SIX homeobox 3 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLN | sarcolipin |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNX24 | sorting nexin 24 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SRP72 | signal recognition particle 72kDa |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| THBS1 | thrombospondin 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM31 | tripartite motif containing 31 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| USP29 | ubiquitin specific peptidase 29 |
| VGF | VGF nerve growth factor inducible |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ALPK1 | alpha-kinase 1 |
| ANO10 | anoctamin 10 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APOL6 | apolipoprotein L, 6 |
| ASPN | asporin |
| ATF1 | activating transcription factor 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CBR1 | carbonyl reductase 1 |
| CD151 | CD151 molecule (Raph blood group) |
| CD1D | CD1d molecule |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLEC2D | C-type lectin domain family 2, member D |
| CORO7 | coronin 7 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DIXDC1 | DIX domain containing 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DOLPP1 | dolichyldiphosphatase 1 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EVL | Enah/Vasp-like |
| FAM193B | family with sequence similarity 193, member B |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FHOD1 | formin homology 2 domain containing 1 |
| FPGS | folylpolyglutamate synthase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH3 | G patch domain containing 3 |
| GPR132 | G protein-coupled receptor 132 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3G | histone cluster 1, H3g |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IRX5 | iroquois homeobox 5 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIF18A | kinesin family member 18A |
| KIF20A | kinesin family member 20A |
| KPTN | kaptin (actin binding protein) |
| MAGEH1 | melanoma antigen family H1 |
| MED15 | mediator complex subunit 15 |
| METTL8 | methyltransferase like 8 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MKRN3 | makorin ring finger protein 3 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL28 | mitochondrial ribosomal protein L28 |
| MTMR6 | myotubularin related protein 6 |
| MXD3 | MAX dimerization protein 3 |
| MYL5 | myosin, light chain 5, regulatory |
| NAG18 | NAG18 mRNA |
| NDE1 | nudE neurodevelopment protein 1 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PMCH | pro-melanin-concentrating hormone |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRAF2 | PRA1 domain family, member 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF25 | ring finger protein 25 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEC24B | SEC24 family member B |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SHPK | sedoheptulokinase |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STBD1 | starch binding domain 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM8A | transmembrane protein 8A |
| TPM3 | tropomyosin 3 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| USP18 | ubiquitin specific peptidase 18 |
| WDR45B | WD repeat domain 45B |
| ZNF85 | zinc finger protein 85 |