urapidil-5295 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the urapidil-5295 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ALCAM activated leukocyte cell adhesion molecule
ASPH aspartate beta-hydroxylase
BBS9 Bardet-Biedl syndrome 9
BLVRA biliverdin reductase A
BMP1 bone morphogenetic protein 1
BMP15 bone morphogenetic protein 15
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC93 coiled-coil domain containing 93
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDK17 cyclin-dependent kinase 17
CEP162 centrosomal protein 162kDa
CEP85 centrosomal protein 85kDa
CGA glycoprotein hormones, alpha polypeptide
CIDEB cell death-inducing DFFA-like effector b
CLCN7 chloride channel, voltage-sensitive 7
CNGB3 cyclic nucleotide gated channel beta 3
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL6A1 collagen, type VI, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CTBS chitobiase, di-N-acetyl-
DLC1 DLC1 Rho GTPase activating protein
DMC1 DNA meiotic recombinase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNA dystrobrevin, alpha
EFNA3 ephrin-A3
ELMO3 engulfment and cell motility 3
EML2 echinoderm microtubule associated protein like 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EWSR1 EWS RNA-binding protein 1
EXOC7 exocyst complex component 7
FAM204A family with sequence similarity 204, member A
FCF1 FCF1 rRNA-processing protein
FCHO1 FCH domain only 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GOLGA8B golgin A8 family, member B
GPC4 glypican 4
HFE hemochromatosis
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HPS1 Hermansky-Pudlak syndrome 1
HPS4 Hermansky-Pudlak syndrome 4
IFT22 intraflagellar transport 22
IL1R1 interleukin 1 receptor, type I
IPO9 importin 9
ITSN1 intersectin 1 (SH3 domain protein)
JRK Jrk homolog (mouse)
LHX2 LIM homeobox 2
LIG3 ligase III, DNA, ATP-dependent
LPIN1 lipin 1
LTBP4 latent transforming growth factor beta binding protein 4
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MICALL1 MICAL-like 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOSPD3 motile sperm domain containing 3
MPPE1 metallophosphoesterase 1
MXD3 MAX dimerization protein 3
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NGLY1 N-glycanase 1
PDGFA platelet-derived growth factor alpha polypeptide
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLK4 polo-like kinase 4
PYGB phosphorylase, glycogen; brain
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD52 RAD52 homolog (S. cerevisiae)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A4 S100 calcium binding protein A4
SAMD4A sterile alpha motif domain containing 4A
SAPCD1 suppressor APC domain containing 1
SBF1 SET binding factor 1
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SPRY2 sprouty homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCP10 t-complex 10
TMEM231 transmembrane protein 231
TPM1 tropomyosin 1 (alpha)
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC10 trafficking protein particle complex 10
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN31 tetraspanin 31
TUBA3C tubulin, alpha 3c
VAC14 Vac14 homolog (S. cerevisiae)
ZER1 zyg-11 related, cell cycle regulator
ZNF318 zinc finger protein 318
ZNF480 zinc finger protein 480
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKRD46 ankyrin repeat domain 46
ANXA2P3 annexin A2 pseudogene 3
APOD apolipoprotein D
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARRB2 arrestin, beta 2
ATG14 autophagy related 14
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP7B ATPase, Cu++ transporting, beta polypeptide
BAGE B melanoma antigen
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF40 chromosome 19 open reading frame 40
C9ORF40 chromosome 9 open reading frame 40
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA1 calmodulin binding transcription activator 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP97 centrosomal protein 97kDa
CHST10 carbohydrate sulfotransferase 10
CLEC16A C-type lectin domain family 16, member A
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COQ3 coenzyme Q3 methyltransferase
CORO1A coronin, actin binding protein, 1A
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRIPT cysteine-rich PDZ-binding protein
CRYL1 crystallin, lambda 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXORF56 chromosome X open reading frame 56
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM1 dynamin 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFHD1 EF-hand domain family, member D1
EPPK1 epiplakin 1
ETAA1 Ewing tumor-associated antigen 1
EXOC5 exocyst complex component 5
FAM169A family with sequence similarity 169, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FIP1L1 factor interacting with PAPOLA and CPSF1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FSD1 fibronectin type III and SPRY domain containing 1
GAR1 GAR1 ribonucleoprotein
GFOD2 glucose-fructose oxidoreductase domain containing 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
IDI2-AS1 IDI2 antisense RNA 1
IRF9 interferon regulatory factor 9
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIF13B kinesin family member 13B
KLHL36 kelch-like family member 36
KRI1 KRI1 homolog (S. cerevisiae)
LAMA3 laminin, alpha 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL1 methyltransferase like 1
MMP9 matrix metallopeptidase 9
MORC3 MORC family CW-type zinc finger 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NOTCH1 notch 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PGP phosphoglycolate phosphatase
PHKG2 phosphorylase kinase, gamma 2 (testis)
PRAF2 PRA1 domain family, member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PROS1 protein S (alpha)
PUS3 pseudouridylate synthase 3
RANBP17 RAN binding protein 17
REPS2 RALBP1 associated Eps domain containing 2
RFTN1 raftlin, lipid raft linker 1
RNF31 ring finger protein 31
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SHARPIN SHANK-associated RH domain interactor
SIK1 salt-inducible kinase 1
SMIM8 small integral membrane protein 8
SND1-IT1 SND1 intronic transcript 1
SSBP3 single stranded DNA binding protein 3
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TCTN2 tectonic family member 2
TM7SF3 transmembrane 7 superfamily member 3
TMUB2 transmembrane and ubiquitin-like domain containing 2
UBE2O ubiquitin-conjugating enzyme E2O
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF124 zinc finger protein 124
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF35 zinc finger protein 35
ZNF639 zinc finger protein 639
ZNF668 zinc finger protein 668
ZNF669 zinc finger protein 669