urapidil-6455 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the urapidil-6455 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRE2 adhesion G protein-coupled receptor E2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADRBK1 adrenergic, beta, receptor kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMPD3 adenosine monophosphate deaminase 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BTG2 BTG family, member 2
C2ORF27A chromosome 2 open reading frame 27A
CALD1 caldesmon 1
CCDC28B coiled-coil domain containing 28B
CD101 CD101 molecule
CD52 CD52 molecule
CD7 CD7 molecule
CDC25A cell division cycle 25A
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEP162 centrosomal protein 162kDa
CLDN14 claudin 14
COL6A1 collagen, type VI, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CST4 cystatin S
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CXCL9 chemokine (C-X-C motif) ligand 9
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCAF11 DDB1 and CUL4 associated factor 11
DFNB31 deafness, autosomal recessive 31
DKKL1 dickkopf-like 1
DNAI2 dynein, axonemal, intermediate chain 2
ESR1 estrogen receptor 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GGT1 gamma-glutamyltransferase 1
GJA4 gap junction protein, alpha 4, 37kDa
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR27 G protein-coupled receptor 27
GRK5 G protein-coupled receptor kinase 5
GZMM granzyme M (lymphocyte met-ase 1)
HAS2 hyaluronan synthase 2
HIST1H2BL histone cluster 1, H2bl
HOXA10 homeobox A10
IGHM immunoglobulin heavy constant mu
IL1R2 interleukin 1 receptor, type II
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA1109 KIAA1109
KRT15 keratin 15, type I
KRT83 keratin 83, type II
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC23 leucine rich repeat containing 23
LUZP4 leucine zipper protein 4
MAOA monoamine oxidase A
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MEFV Mediterranean fever
MEG3 maternally expressed 3 (non-protein coding)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NEK9 NIMA-related kinase 9
NOS2 nitric oxide synthase 2, inducible
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTS neurotensin
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX5 paired box 5
PAX6 paired box 6
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PGLYRP4 peptidoglycan recognition protein 4
PHF7 PHD finger protein 7
PITX1 paired-like homeodomain 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKG2 protein kinase, cGMP-dependent, type II
PRY PTPN13-like, Y-linked
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASAL2 RAS protein activator like 2
RGS12 regulator of G-protein signaling 12
RRBP1 ribosome binding protein 1
SCLY selenocysteine lyase
SIK3 SIK family kinase 3
SIRT5 sirtuin 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPTBN2 spectrin, beta, non-erythrocytic 2
STATH statherin
TCP11L1 t-complex 11, testis-specific-like 1
TGFB2 transforming growth factor, beta 2
THY1 Thy-1 cell surface antigen
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
VPREB3 pre-B lymphocyte 3
ZBTB44 zinc finger and BTB domain containing 44
ZNF532 zinc finger protein 532
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ADAM2 ADAM metallopeptidase domain 2
ADTRP androgen-dependent TFPI-regulating protein
AFAP1 actin filament associated protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX15 arachidonate 15-lipoxygenase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C1ORF159 chromosome 1 open reading frame 159
CALCOCO1 calcium binding and coiled-coil domain 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CLDN15 claudin 15
CTC1 CTS telomere maintenance complex component 1
DMTN dematin actin binding protein
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
FAM114A2 family with sequence similarity 114, member A2
FAM184A family with sequence similarity 184, member A
FAM186A family with sequence similarity 186, member A
FBXO31 F-box protein 31
FGF23 fibroblast growth factor 23
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALK1 galactokinase 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPC3 glypican 3
GRPR gastrin-releasing peptide receptor
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HPS6 Hermansky-Pudlak syndrome 6
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
INO80D INO80 complex subunit D
KLF3 Kruppel-like factor 3 (basic)
LHX1 LIM homeobox 1
LINC00597 long intergenic non-protein coding RNA 597
LOC100131532 uncharacterized LOC100131532
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOXL3 lysyl oxidase-like 3
LZTR1 leucine-zipper-like transcription regulator 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MCOLN3 mucolipin 3
MRPS18C mitochondrial ribosomal protein S18C
MTERF4 mitochondrial transcription termination factor 4
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NES nestin
NOL6 nucleolar protein 6 (RNA-associated)
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PADI1 peptidyl arginine deiminase, type I
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PILRB paired immunoglobin-like type 2 receptor beta
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRMT7 protein arginine methyltransferase 7
PROL1 proline rich, lacrimal 1
RANGRF RAN guanine nucleotide release factor
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN2 Ras and Rab interactor 2
RNF2 ring finger protein 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3B RUN domain containing 3B
SCAI suppressor of cancer cell invasion
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SNX15 sorting nexin 15
STON1 stonin 1
TDRD7 tudor domain containing 7
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTBK2 tau tubulin kinase 2
UBTD1 ubiquitin domain containing 1
USP18 ubiquitin specific peptidase 18
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZSWIM1 zinc finger, SWIM-type containing 1