urea cycle Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. (Gene Ontology, GO_0000050)
External Link http://amigo.geneontology.org/amigo/term/GO:0000050
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Genes

12 genes participating in the urea cycle biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
ARG1 arginase 1
ARG2 arginase 2
ASL argininosuccinate lyase
ASS1 argininosuccinate synthase 1
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
HTT huntingtin
NAGS N-acetylglutamate synthase
OTC ornithine carbamoyltransferase
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2