urea cycle Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. (Gene Ontology, GO_0000050)
External Link	http://amigo.geneontology.org/amigo/term/GO:0000050
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Genes

7 genes participating in the urea cycle biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
ASS1	argininosuccinate synthase 1
LDLR	low density lipoprotein receptor
NAGS	N-acetylglutamate synthase
OTC	ornithine carbamoyltransferase
PM20D1	peptidase M20 domain containing 1
SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A2	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2