uropod Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively. (Gene Ontology, GO_0001931)
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Genes

104 proteins co-occuring with the uropod cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ICAM3 intercellular adhesion molecule 3 1.48305
MSN moesin 1.45816
EZR ezrin 1.37023
RDX radixin 1.31897
SELPLG selectin P ligand 1.31142
ICAM1 intercellular adhesion molecule 1 1.10613
CXCL12 chemokine (C-X-C motif) ligand 12 1.00399
CD44 CD44 molecule (Indian blood group) 0.98488
FLOT1 flotillin 1 0.955439
CTSZ cathepsin Z 0.817616
ZBTB20 zinc finger and BTB domain containing 20 0.811652
FLOT2 flotillin 2 0.787359
SPN sialophorin 0.783698
RHOT2 ras homolog family member T2 0.755437
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.731973
SYTL5 synaptotagmin-like 5 0.65259
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.631598
CDC42 cell division cycle 42 0.628187
LPAR2 lysophosphatidic acid receptor 2 0.591392
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.589714
SEPT5 septin 5 0.538649
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.531258
LPAR4 lysophosphatidic acid receptor 4 0.515716
VAV1 vav 1 guanine nucleotide exchange factor 0.514085
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.501881
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.487307
SELL selectin L 0.48005
ICAM2 intercellular adhesion molecule 2 0.454418
IL15 interleukin 15 0.454418
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.446465
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.444482
BST1 bone marrow stromal cell antigen 1 0.43617
CCR2 chemokine (C-C motif) receptor 2 0.431435
DPYSL2 dihydropyrimidinase-like 2 0.424353
CCL21 chemokine (C-C motif) ligand 21 0.423174
CCR7 chemokine (C-C motif) receptor 7 0.422389
SHARPIN SHANK-associated RH domain interactor 0.417685
TUBA1B tubulin, alpha 1b 0.413382
KIDINS220 kinase D-interacting substrate, 220kDa 0.409869
ORAI1 ORAI calcium release-activated calcium modulator 1 0.408309
VCAM1 vascular cell adhesion molecule 1 0.402859
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.391228
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.366623
SYK spleen tyrosine kinase 0.360133
SHPK sedoheptulokinase 0.355563
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.349484
RHOT1 ras homolog family member T1 0.34645
MYLK myosin light chain kinase 0.344935
CTSK cathepsin K 0.339639
SNX27 sorting nexin family member 27 0.338128
CD4 CD4 molecule 0.331342
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.328708
ISL1 ISL LIM homeobox 1 0.324576
BICD2 bicaudal D homolog 2 (Drosophila) 0.324576
DNM2 dynamin 2 0.318205
SRCIN1 SRC kinase signaling inhibitor 1 0.311851
PLSCR1 phospholipid scramblase 1 0.300682
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.298455
CD34 CD34 molecule 0.296601
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.27998
MCF2 MCF.2 cell line derived transforming sequence 0.263485
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.262025
MYH9 myosin, heavy chain 9, non-muscle 0.26166
C5AR1 complement component 5a receptor 1 0.259837
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.258745
MST1 macrophage stimulating 1 0.251476
PKN1 protein kinase N1 0.248216
FYB FYN binding protein 0.240996
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.240996
PLAUR plasminogen activator, urokinase receptor 0.229888
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.227397
FN1 fibronectin 1 0.227397
SDC1 syndecan 1 0.22385
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.22173
HAX1 HCLS1 associated protein X-1 0.219617
OSGEP O-sialoglycoprotein endopeptidase 0.21646
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.21646
RAB27A RAB27A, member RAS oncogene family 0.213669
SELE selectin E 0.212974
GYPE glycophorin E (MNS blood group) 0.21124
CNOT1 CCR4-NOT transcription complex, subunit 1 0.202009
GPC1 glypican 1 0.199325
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.199325
MARCKS myristoylated alanine-rich protein kinase C substrate 0.198991
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.197993
WAS Wiskott-Aldrich syndrome 0.197662
SFTPA1 surfactant protein A1 0.194698
CXCR5 chemokine (C-X-C motif) receptor 5 0.19307
MCM6 minichromosome maintenance complex component 6 0.191777
STX8 syntaxin 8 0.191456
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.189857
RAB27B RAB27B, member RAS oncogene family 0.183025
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.182122
PRIMA1 proline rich membrane anchor 1 0.180339
SYT7 synaptotagmin VII 0.175466
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.174635
CXCL8 chemokine (C-X-C motif) ligand 8 0.172201
LEPR leptin receptor 0.17141
CLTC clathrin, heavy chain (Hc) 0.170629
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.168598
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.16298
STIM1 stromal interaction molecule 1 0.16233
PF4 platelet factor 4 0.157578
HRH2 histamine receptor H2 0.156513