Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the ursodeoxycholic acid-6484 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
AK2 | adenylate kinase 2 |
ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
APOM | apolipoprotein M |
ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
C19ORF40 | chromosome 19 open reading frame 40 |
CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
CCDC181 | coiled-coil domain containing 181 |
CD79B | CD79b molecule, immunoglobulin-associated beta |
CDADC1 | cytidine and dCMP deaminase domain containing 1 |
COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
DCAF4 | DDB1 and CUL4 associated factor 4 |
DCTN2 | dynactin 2 (p50) |
DKKL1 | dickkopf-like 1 |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
DPYS | dihydropyrimidinase |
EDA | ectodysplasin A |
EFS | embryonal Fyn-associated substrate |
ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
FBLN1 | fibulin 1 |
FLJ11710 | uncharacterized protein FLJ11710 |
G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
GUCA2A | guanylate cyclase activator 2A (guanylin) |
HCAR3 | hydroxycarboxylic acid receptor 3 |
HFE | hemochromatosis |
HLF | hepatic leukemia factor |
HOXA10 | homeobox A10 |
HP1BP3 | heterochromatin protein 1, binding protein 3 |
HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
HYAL4 | hyaluronoglucosaminidase 4 |
IGFBP5 | insulin-like growth factor binding protein 5 |
JRK | Jrk homolog (mouse) |
KANK1 | KN motif and ankyrin repeat domains 1 |
KCTD17 | potassium channel tetramerization domain containing 17 |
KRIT1 | KRIT1, ankyrin repeat containing |
LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
LPA | lipoprotein, Lp(a) |
LRRC37A3 | leucine rich repeat containing 37, member A3 |
LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
MATK | megakaryocyte-associated tyrosine kinase |
MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
MPL | MPL proto-oncogene, thrombopoietin receptor |
MST1 | macrophage stimulating 1 |
MTRF1L | mitochondrial translational release factor 1-like |
MX2 | MX dynamin-like GTPase 2 |
MYLK | myosin light chain kinase |
NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
NHLH1 | nescient helix loop helix 1 |
OCA2 | oculocutaneous albinism II |
OSBPL10 | oxysterol binding protein-like 10 |
PAWR | PRKC, apoptosis, WT1, regulator |
PCDHB17P | protocadherin beta 17 pseudogene |
PER1 | period circadian clock 1 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
PLEK | pleckstrin |
POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 |
POLL | polymerase (DNA directed), lambda |
POU4F2 | POU class 4 homeobox 2 |
PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
PPP5C | protein phosphatase 5, catalytic subunit |
PRKCB | protein kinase C, beta |
PROSC | proline synthetase co-transcribed homolog (bacterial) |
PYY | peptide YY |
RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
RBM12B | RNA binding motif protein 12B |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
RPL18 | ribosomal protein L18 |
RUSC2 | RUN and SH3 domain containing 2 |
SAFB | scaffold attachment factor B |
SBNO1 | strawberry notch homolog 1 (Drosophila) |
SCN11A | sodium channel, voltage gated, type XI alpha subunit |
SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
SIX1 | SIX homeobox 1 |
SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
SNAP25 | synaptosomal-associated protein, 25kDa |
SPRY4 | sprouty homolog 4 (Drosophila) |
SYNJ1 | synaptojanin 1 |
TEF | thyrotrophic embryonic factor |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPMT | thiopurine S-methyltransferase |
TRIM2 | tripartite motif containing 2 |
UTS2 | urotensin 2 |
VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
WNT6 | wingless-type MMTV integration site family, member 6 |
ZNF222 | zinc finger protein 222 |
ZNF280A | zinc finger protein 280A |
ZNF551 | zinc finger protein 551 |
ZNF75D | zinc finger protein 75D |
Symbol | Name |
---|---|
ACTL8 | actin-like 8 |
ADGRE5 | adhesion G protein-coupled receptor E5 |
ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
ANP32A-IT1 | ANP32A intronic transcript 1 |
ANXA1 | annexin A1 |
APLP1 | amyloid beta (A4) precursor-like protein 1 |
ASCC2 | activating signal cointegrator 1 complex subunit 2 |
ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
BAHD1 | bromo adjacent homology domain containing 1 |
BBC3 | BCL2 binding component 3 |
BIRC7 | baculoviral IAP repeat containing 7 |
C5 | complement component 5 |
C5ORF45 | chromosome 5 open reading frame 45 |
C8ORF60 | chromosome 8 open reading frame 60 |
CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
CCDC186 | coiled-coil domain containing 186 |
CCNO | cyclin O |
CDH10 | cadherin 10, type 2 (T2-cadherin) |
CENPO | centromere protein O |
CFAP44 | cilia and flagella associated protein 44 |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
COQ6 | coenzyme Q6 monooxygenase |
DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
DEAF1 | DEAF1 transcription factor |
DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
DNAL4 | dynein, axonemal, light chain 4 |
EAF2 | ELL associated factor 2 |
EMID1 | EMI domain containing 1 |
ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
EXD3 | exonuclease 3'-5' domain containing 3 |
FANCE | Fanconi anemia, complementation group E |
FCHO1 | FCH domain only 1 |
FUZ | fuzzy planar cell polarity protein |
GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
GPR87 | G protein-coupled receptor 87 |
GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
HAMP | hepcidin antimicrobial peptide |
HIST1H4A | histone cluster 1, H4a |
HOXA4 | homeobox A4 |
IGFBP6 | insulin-like growth factor binding protein 6 |
IL15RA | interleukin 15 receptor, alpha |
KAT2A | K(lysine) acetyltransferase 2A |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KDM5C | lysine (K)-specific demethylase 5C |
KIAA0355 | KIAA0355 |
LAMA3 | laminin, alpha 3 |
LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
LRP3 | low density lipoprotein receptor-related protein 3 |
MANBA | mannosidase, beta A, lysosomal |
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
MAST3 | microtubule associated serine/threonine kinase 3 |
MBIP | MAP3K12 binding inhibitory protein 1 |
MBNL3 | muscleblind-like splicing regulator 3 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
NKX3-2 | NK3 homeobox 2 |
NRGN | neurogranin (protein kinase C substrate, RC3) |
PAQR6 | progestin and adipoQ receptor family member VI |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
PDGFD | platelet derived growth factor D |
PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
PLD2 | phospholipase D2 |
PTDSS2 | phosphatidylserine synthase 2 |
RAB36 | RAB36, member RAS oncogene family |
RHBG | Rh family, B glycoprotein (gene/pseudogene) |
RNF122 | ring finger protein 122 |
RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
SALL2 | spalt-like transcription factor 2 |
SAYSD1 | SAYSVFN motif domain containing 1 |
SETD1A | SET domain containing 1A |
SHARPIN | SHANK-associated RH domain interactor |
SKA1 | spindle and kinetochore associated complex subunit 1 |
SLC12A8 | solute carrier family 12, member 8 |
SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SNORA21 | small nucleolar RNA, H/ACA box 21 |
SYNC | syncoilin, intermediate filament protein |
TRDMT1 | tRNA aspartic acid methyltransferase 1 |
TTLL1 | tubulin tyrosine ligase-like family member 1 |
TWF2 | twinfilin actin binding protein 2 |
UNC119 | unc-119 homolog (C. elegans) |
VAV1 | vav 1 guanine nucleotide exchange factor |
VIM | vimentin |
XYLT2 | xylosyltransferase II |
YIPF5 | Yip1 domain family, member 5 |
ZFAND3 | zinc finger, AN1-type domain 3 |
ZNF623 | zinc finger protein 623 |
ZNF787 | zinc finger protein 787 |
ZNF816 | zinc finger protein 816 |