Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the ursolic acid-2067 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
ADCY1 | adenylate cyclase 1 (brain) |
ADRBK1 | adrenergic, beta, receptor kinase 1 |
ADRBK2 | adrenergic, beta, receptor kinase 2 |
AKAP13 | A kinase (PRKA) anchor protein 13 |
ALK | anaplastic lymphoma receptor tyrosine kinase |
ANGPTL4 | angiopoietin-like 4 |
APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
ASAP1-IT1 | ASAP1 intronic transcript 1 |
ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
BMP4 | bone morphogenetic protein 4 |
C1QL1 | complement component 1, q subcomponent-like 1 |
CCNJ | cyclin J |
CCR7 | chemokine (C-C motif) receptor 7 |
CHI3L2 | chitinase 3-like 2 |
COL6A1 | collagen, type VI, alpha 1 |
CPA4 | carboxypeptidase A4 |
CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
DEAF1 | DEAF1 transcription factor |
DHODH | dihydroorotate dehydrogenase (quinone) |
DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 |
EDNRA | endothelin receptor type A |
ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
EML2 | echinoderm microtubule associated protein like 2 |
F11R | F11 receptor |
FAM178A | family with sequence similarity 178, member A |
FCMR | Fc fragment of IgM receptor |
FOXO1 | forkhead box O1 |
FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
GNPDA1 | glucosamine-6-phosphate deaminase 1 |
GPR4 | G protein-coupled receptor 4 |
HMOX1 | heme oxygenase 1 |
HOOK1 | hook microtubule-tethering protein 1 |
IGF1R | insulin-like growth factor 1 receptor |
IGFBP5 | insulin-like growth factor binding protein 5 |
IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
ING4 | inhibitor of growth family, member 4 |
INSIG1 | insulin induced gene 1 |
ITPKC | inositol-trisphosphate 3-kinase C |
JUN | jun proto-oncogene |
KDM5A | lysine (K)-specific demethylase 5A |
KIAA1644 | KIAA1644 |
KIF1C | kinesin family member 1C |
KPNA5 | karyopherin alpha 5 (importin alpha 6) |
KRT75 | keratin 75, type II |
L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
LARGE | like-glycosyltransferase |
LDLR | low density lipoprotein receptor |
LRP2 | low density lipoprotein receptor-related protein 2 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
LRRN2 | leucine rich repeat neuronal 2 |
MANBA | mannosidase, beta A, lysosomal |
MBTD1 | mbt domain containing 1 |
MEF2A | myocyte enhancer factor 2A |
MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
MSL3 | male-specific lethal 3 homolog (Drosophila) |
MUC1 | mucin 1, cell surface associated |
MYRF | myelin regulatory factor |
NCAPH2 | non-SMC condensin II complex, subunit H2 |
NF2 | neurofibromin 2 (merlin) |
NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
NKX3-2 | NK3 homeobox 2 |
NMT2 | N-myristoyltransferase 2 |
NUCB1 | nucleobindin 1 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
PSENEN | presenilin enhancer gamma secretase subunit |
RIN1 | Ras and Rab interactor 1 |
RPGRIP1L | RPGRIP1-like |
RPL23 | ribosomal protein L23 |
RPLP2 | ribosomal protein, large, P2 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SLC17A2 | solute carrier family 17, member 2 |
SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
SP100 | SP100 nuclear antigen |
SPHK2 | sphingosine kinase 2 |
SQLE | squalene epoxidase |
SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
TBC1D30 | TBC1 domain family, member 30 |
TRA2A | transformer 2 alpha homolog (Drosophila) |
TRIM29 | tripartite motif containing 29 |
UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
USP27X | ubiquitin specific peptidase 27, X-linked |
VWA1 | von Willebrand factor A domain containing 1 |
VWA8 | von Willebrand factor A domain containing 8 |
WDR4 | WD repeat domain 4 |
ZMYM2 | zinc finger, MYM-type 2 |
ZNF117 | zinc finger protein 117 |
ZNF385D | zinc finger protein 385D |
Symbol | Name |
---|---|
ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
ADCY6 | adenylate cyclase 6 |
APOLD1 | apolipoprotein L domain containing 1 |
ARID4A | AT rich interactive domain 4A (RBP1-like) |
ARRB2 | arrestin, beta 2 |
AUH | AU RNA binding protein/enoyl-CoA hydratase |
AURKB | aurora kinase B |
AXIN1 | axin 1 |
BACE1 | beta-site APP-cleaving enzyme 1 |
BAHD1 | bromo adjacent homology domain containing 1 |
BCL9 | B-cell CLL/lymphoma 9 |
BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
BLMH | bleomycin hydrolase |
C1ORF56 | chromosome 1 open reading frame 56 |
CAMTA2 | calmodulin binding transcription activator 2 |
CHMP6 | charged multivesicular body protein 6 |
CLASP1 | cytoplasmic linker associated protein 1 |
CLEC16A | C-type lectin domain family 16, member A |
CNGB3 | cyclic nucleotide gated channel beta 3 |
CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
CRYBA2 | crystallin, beta A2 |
CST4 | cystatin S |
CXORF56 | chromosome X open reading frame 56 |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
DMTF1 | cyclin D binding myb-like transcription factor 1 |
DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
EPN3 | epsin 3 |
EPPK1 | epiplakin 1 |
ERF | Ets2 repressor factor |
FBXO2 | F-box protein 2 |
FGD1 | FYVE, RhoGEF and PH domain containing 1 |
GAMT | guanidinoacetate N-methyltransferase |
GDAP2 | ganglioside induced differentiation associated protein 2 |
GLI3 | GLI family zinc finger 3 |
GLT8D2 | glycosyltransferase 8 domain containing 2 |
GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
GPR176 | G protein-coupled receptor 176 |
GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
HDAC7 | histone deacetylase 7 |
HOXC10 | homeobox C10 |
HSPB8 | heat shock 22kDa protein 8 |
ILK | integrin-linked kinase |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KIAA0232 | KIAA0232 |
KIAA0753 | KIAA0753 |
KRT4 | keratin 4, type II |
MAST3 | microtubule associated serine/threonine kinase 3 |
ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
MFSD12 | major facilitator superfamily domain containing 12 |
MOGS | mannosyl-oligosaccharide glucosidase |
MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
NPM3 | nucleophosmin/nucleoplasmin 3 |
NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
NT5DC3 | 5'-nucleotidase domain containing 3 |
NT5E | 5'-nucleotidase, ecto (CD73) |
NT5M | 5',3'-nucleotidase, mitochondrial |
NUBP2 | nucleotide binding protein 2 |
NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
OCEL1 | occludin/ELL domain containing 1 |
ORAI3 | ORAI calcium release-activated calcium modulator 3 |
PAQR4 | progestin and adipoQ receptor family member IV |
PARD6A | par-6 family cell polarity regulator alpha |
PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
POMT2 | protein-O-mannosyltransferase 2 |
PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
PROSER1 | proline and serine rich 1 |
PSAT1 | phosphoserine aminotransferase 1 |
RAB17 | RAB17, member RAS oncogene family |
REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
RNF25 | ring finger protein 25 |
SCML2 | sex comb on midleg-like 2 (Drosophila) |
SEC14L2 | SEC14-like 2 (S. cerevisiae) |
SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
SESN1 | sestrin 1 |
SH2D2A | SH2 domain containing 2A |
SNPH | syntaphilin |
SPEG | SPEG complex locus |
STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
STK16 | serine/threonine kinase 16 |
STX5 | syntaxin 5 |
TIMP4 | TIMP metallopeptidase inhibitor 4 |
TPCN1 | two pore segment channel 1 |
TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
TTC23 | tetratricopeptide repeat domain 23 |
USP18 | ubiquitin specific peptidase 18 |
YEATS4 | YEATS domain containing 4 |
ZFYVE16 | zinc finger, FYVE domain containing 16 |
ZNF232 | zinc finger protein 232 |
ZNF701 | zinc finger protein 701 |