Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the ursolic acid-2230 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACVR1B | activin A receptor, type IB |
ADGRA2 | adhesion G protein-coupled receptor A2 |
AKR1C1 | aldo-keto reductase family 1, member C1 |
APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
AQP3 | aquaporin 3 (Gill blood group) |
ARPIN | actin-related protein 2/3 complex inhibitor |
ATF3 | activating transcription factor 3 |
BHLHE40 | basic helix-loop-helix family, member e40 |
BIRC3 | baculoviral IAP repeat containing 3 |
CASP2 | caspase 2, apoptosis-related cysteine peptidase |
CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
CEMIP | cell migration inducing protein, hyaluronan binding |
CFLAR | CASP8 and FADD-like apoptosis regulator |
COL17A1 | collagen, type XVII, alpha 1 |
COL19A1 | collagen, type XIX, alpha 1 |
CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
CTBP2 | C-terminal binding protein 2 |
CTNS | cystinosin, lysosomal cystine transporter |
DAPK1 | death-associated protein kinase 1 |
DOPEY2 | dopey family member 2 |
DUSP4 | dual specificity phosphatase 4 |
EGFR | epidermal growth factor receptor |
EGR1 | early growth response 1 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FOS | FBJ murine osteosarcoma viral oncogene homolog |
GEM | GTP binding protein overexpressed in skeletal muscle |
GINS4 | GINS complex subunit 4 (Sld5 homolog) |
GLB1L | galactosidase, beta 1-like |
GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
GOLGA8A | golgin A8 family, member A |
GUSBP3 | glucuronidase, beta pseudogene 3 |
HFE | hemochromatosis |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMOX1 | heme oxygenase 1 |
HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
ICAM1 | intercellular adhesion molecule 1 |
IL6ST | interleukin 6 signal transducer |
INHBE | inhibin, beta E |
INSIG1 | insulin induced gene 1 |
ISG20 | interferon stimulated exonuclease gene 20kDa |
ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
JAG1 | jagged 1 |
JUN | jun proto-oncogene |
KLF2 | Kruppel-like factor 2 |
KLF6 | Kruppel-like factor 6 |
KLHL20 | kelch-like family member 20 |
KLHL24 | kelch-like family member 24 |
LIF | leukemia inhibitory factor |
LPIN1 | lipin 1 |
LYST | lysosomal trafficking regulator |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MALL | mal, T-cell differentiation protein-like |
MBNL2 | muscleblind-like splicing regulator 2 |
MECOM | MDS1 and EVI1 complex locus |
MED18 | mediator complex subunit 18 |
MEX3D | mex-3 RNA binding family member D |
MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
MIP | major intrinsic protein of lens fiber |
MKL1 | megakaryoblastic leukemia (translocation) 1 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
NID1 | nidogen 1 |
NIPAL3 | NIPA-like domain containing 3 |
OAZ3 | ornithine decarboxylase antizyme 3 |
OMD | osteomodulin |
PARD6B | par-6 family cell polarity regulator beta |
PARP3 | poly (ADP-ribose) polymerase family, member 3 |
PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PKNOX2 | PBX/knotted 1 homeobox 2 |
PLCB2 | phospholipase C, beta 2 |
PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
PSD3 | pleckstrin and Sec7 domain containing 3 |
PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
RND1 | Rho family GTPase 1 |
SERHL2 | serine hydrolase-like 2 |
SFTPC | surfactant protein C |
SKIL | SKI-like proto-oncogene |
SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
T | T, brachyury homolog (mouse) |
TEP1 | telomerase-associated protein 1 |
TGFB2 | transforming growth factor, beta 2 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TMEM209 | transmembrane protein 209 |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TRIM29 | tripartite motif containing 29 |
TWF1 | twinfilin actin binding protein 1 |
WNK1 | WNK lysine deficient protein kinase 1 |
XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
YPEL1 | yippee-like 1 (Drosophila) |
ZMYND8 | zinc finger, MYND-type containing 8 |
ZNF652 | zinc finger protein 652 |
Symbol | Name |
---|---|
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ARRB1 | arrestin, beta 1 |
AUP1 | ancient ubiquitous protein 1 |
BAHCC1 | BAH domain and coiled-coil containing 1 |
BCL7B | B-cell CLL/lymphoma 7B |
BTBD2 | BTB (POZ) domain containing 2 |
C11ORF80 | chromosome 11 open reading frame 80 |
C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
CCNE1 | cyclin E1 |
CCP110 | centriolar coiled coil protein 110kDa |
CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
CENPT | centromere protein T |
CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
CRIP1 | cysteine-rich protein 1 (intestinal) |
CUL9 | cullin 9 |
DPY19L1P1 | DPY19L1 pseudogene 1 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
DYSF | dysferlin |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
ELOVL4 | ELOVL fatty acid elongase 4 |
ELSPBP1 | epididymal sperm binding protein 1 |
ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
ETNK2 | ethanolamine kinase 2 |
FBXL7 | F-box and leucine-rich repeat protein 7 |
FOXD1 | forkhead box D1 |
FSD1 | fibronectin type III and SPRY domain containing 1 |
GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
GADD45G | growth arrest and DNA-damage-inducible, gamma |
GAMT | guanidinoacetate N-methyltransferase |
GATA4 | GATA binding protein 4 |
HCFC2 | host cell factor C2 |
HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
HIST1H3B | histone cluster 1, H3b |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
ITPKB | inositol-trisphosphate 3-kinase B |
KIAA0319L | KIAA0319-like |
KRT15 | keratin 15, type I |
LIN7A | lin-7 homolog A (C. elegans) |
LY6D | lymphocyte antigen 6 complex, locus D |
LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
MGC12488 | |
MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
MYOZ1 | myozenin 1 |
NABP2 | nucleic acid binding protein 2 |
NLRX1 | NLR family member X1 |
NOD1 | nucleotide-binding oligomerization domain containing 1 |
NPFFR1 | neuropeptide FF receptor 1 |
NPM3 | nucleophosmin/nucleoplasmin 3 |
NT5DC3 | 5'-nucleotidase domain containing 3 |
NXPH4 | neurexophilin 4 |
OLFML2A | olfactomedin-like 2A |
OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
PACS1 | phosphofurin acidic cluster sorting protein 1 |
PAIP2B | poly(A) binding protein interacting protein 2B |
PALM | paralemmin |
PCDHB8 | protocadherin beta 8 |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PKN1 | protein kinase N1 |
POLL | polymerase (DNA directed), lambda |
PRICKLE3 | prickle homolog 3 (Drosophila) |
RAB5C | RAB5C, member RAS oncogene family |
RAD54L2 | RAD54-like 2 (S. cerevisiae) |
RANGRF | RAN guanine nucleotide release factor |
RCAN3 | RCAN family member 3 |
RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
RHBDD3 | rhomboid domain containing 3 |
RPAP1 | RNA polymerase II associated protein 1 |
RPAP2 | RNA polymerase II associated protein 2 |
RPGRIP1L | RPGRIP1-like |
SAYSD1 | SAYSVFN motif domain containing 1 |
SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
TEX40 | testis expressed 40 |
TICAM1 | toll-like receptor adaptor molecule 1 |
TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
TM6SF1 | transmembrane 6 superfamily member 1 |
TMCC2 | transmembrane and coiled-coil domain family 2 |
TMLHE | trimethyllysine hydroxylase, epsilon |
TNS2 | tensin 2 |
TUBA3C | tubulin, alpha 3c |
UNC119 | unc-119 homolog (C. elegans) |
VEGFB | vascular endothelial growth factor B |
WDR33 | WD repeat domain 33 |
WFDC2 | WAP four-disulfide core domain 2 |
XYLT2 | xylosyltransferase II |
ZGPAT | zinc finger, CCCH-type with G patch domain |
ZNF205 | zinc finger protein 205 |
ZNF37BP | zinc finger protein 37B, pseudogene |