ursolic acid-5825 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the ursolic acid-5825 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASIC1 acid sensing (proton gated) ion channel 1
AURKC aurora kinase C
BBC3 BCL2 binding component 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C21ORF2 chromosome 21 open reading frame 2
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CDK17 cyclin-dependent kinase 17
CES2 carboxylesterase 2
CNGB3 cyclic nucleotide gated channel beta 3
CNOT8 CCR4-NOT transcription complex, subunit 8
COL9A3 collagen, type IX, alpha 3
CREM cAMP responsive element modulator
CST4 cystatin S
CTNS cystinosin, lysosomal cystine transporter
DKFZP434C153 DKFZP434C153 protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOCK9 dedicator of cytokinesis 9
DTNB dystrobrevin, beta
ERAP1 endoplasmic reticulum aminopeptidase 1
EXD3 exonuclease 3'-5' domain containing 3
FAM188A family with sequence similarity 188, member A
FCF1 FCF1 rRNA-processing protein
FGFR1 fibroblast growth factor receptor 1
FNDC3A fibronectin type III domain containing 3A
GEMIN8 gem (nuclear organelle) associated protein 8
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GM2A GM2 ganglioside activator
GOLGA1 golgin A1
GSK3A glycogen synthase kinase 3 alpha
GSTM1 glutathione S-transferase mu 1
HAUS5 HAUS augmin-like complex, subunit 5
HOXB2 homeobox B2
HYAL4 hyaluronoglucosaminidase 4
ICAM1 intercellular adhesion molecule 1
INO80D INO80 complex subunit D
IQCE IQ motif containing E
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KERA keratocan
KIAA0753 KIAA0753
KIF5C kinesin family member 5C
KRIT1 KRIT1, ankyrin repeat containing
KRT6B keratin 6B, type II
KRT75 keratin 75, type II
LAMC3 laminin, gamma 3
LARGE like-glycosyltransferase
LIPG lipase, endothelial
LMF2 lipase maturation factor 2
LMTK2 lemur tyrosine kinase 2
LOC257152 uncharacterized LOC257152
LRRC2 leucine rich repeat containing 2
LYPD3 LY6/PLAUR domain containing 3
MAN2A2 mannosidase, alpha, class 2A, member 2
MBTPS1 membrane-bound transcription factor peptidase, site 1
MFGE8 milk fat globule-EGF factor 8 protein
MFN2 mitofusin 2
MIIP migration and invasion inhibitory protein
MRPS12 mitochondrial ribosomal protein S12
MVK mevalonate kinase
OSBPL10 oxysterol binding protein-like 10
OSBPL2 oxysterol binding protein-like 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDS5A PDS5 cohesin associated factor A
PEX10 peroxisomal biogenesis factor 10
PEX11A peroxisomal biogenesis factor 11 alpha
PHKG2 phosphorylase kinase, gamma 2 (testis)
POLL polymerase (DNA directed), lambda
PPARD peroxisome proliferator-activated receptor delta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPRR protein tyrosine phosphatase, receptor type, R
RAD17 RAD17 homolog (S. pombe)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RDX radixin
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SARM1 sterile alpha and TIR motif containing 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDC2 syndecan 2
SH2D3A SH2 domain containing 3A
SIRT3 sirtuin 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLN sarcolipin
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SP100 SP100 nuclear antigen
SQLE squalene epoxidase
SRSF1 serine/arginine-rich splicing factor 1
TADA2A transcriptional adaptor 2A
TANK TRAF family member-associated NFKB activator
TBC1D30 TBC1 domain family, member 30
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TMCC1 transmembrane and coiled-coil domain family 1
TRIM23 tripartite motif containing 23
TSNAXIP1 translin-associated factor X interacting protein 1
TUBGCP2 tubulin, gamma complex associated protein 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZMYM5 zinc finger, MYM-type 5

decreased expression

Symbol Name
ADCY7 adenylate cyclase 7
ADGRF1 adhesion G protein-coupled receptor F1
AHDC1 AT hook, DNA binding motif, containing 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATAD3A ATPase family, AAA domain containing 3A
ATF7IP2 activating transcription factor 7 interacting protein 2
BAHD1 bromo adjacent homology domain containing 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BNC2 basonuclin 2
C11ORF63 chromosome 11 open reading frame 63
C16ORF62 chromosome 16 open reading frame 62
C1ORF159 chromosome 1 open reading frame 159
C4ORF19 chromosome 4 open reading frame 19
C6ORF47 chromosome 6 open reading frame 47
CCDC94 coiled-coil domain containing 94
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEP131 centrosomal protein 131kDa
CFAP69 cilia and flagella associated protein 69
CHMP7 charged multivesicular body protein 7
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
COBL cordon-bleu WH2 repeat protein
CTSK cathepsin K
DCLRE1A DNA cross-link repair 1A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DOCK1 dedicator of cytokinesis 1
DPY19L2P2 DPY19L2 pseudogene 2
ERF Ets2 repressor factor
FAM3A family with sequence similarity 3, member A
FAM53B family with sequence similarity 53, member B
FHOD1 formin homology 2 domain containing 1
FOXJ2 forkhead box J2
FSD1 fibronectin type III and SPRY domain containing 1
FZD8 frizzled class receptor 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GSTT1 glutathione S-transferase theta 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H1T histone cluster 1, H1t
HIST1H2BJ histone cluster 1, H2bj
HS1BP3 HCLS1 binding protein 3
IL17RB interleukin 17 receptor B
JUNB jun B proto-oncogene
KCTD7 potassium channel tetramerization domain containing 7
KIAA0232 KIAA0232
KLHL36 kelch-like family member 36
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMBR1L limb development membrane protein 1-like
LOC730101 uncharacterized LOC730101
LPAR6 lysophosphatidic acid receptor 6
MAP1S microtubule-associated protein 1S
MBD5 methyl-CpG binding domain protein 5
MBTD1 mbt domain containing 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MED9 mediator complex subunit 9
MEIS1 Meis homeobox 1
MYBBP1A MYB binding protein (P160) 1a
NCAPH non-SMC condensin I complex, subunit H
NDE1 nudE neurodevelopment protein 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P3H2 prolyl 3-hydroxylase 2
PADI1 peptidyl arginine deiminase, type I
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAQR6 progestin and adipoQ receptor family member VI
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8B phosphodiesterase 8B
PEX26 peroxisomal biogenesis factor 26
PKN1 protein kinase N1
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PORCN porcupine homolog (Drosophila)
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB17 RAB17, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RNF141 ring finger protein 141
SDC3 syndecan 3
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
STEAP4 STEAP family member 4
TESK2 testis-specific kinase 2
TMCO3 transmembrane and coiled-coil domains 3
USB1 U6 snRNA biogenesis 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR76 WD repeat domain 76
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF385D zinc finger protein 385D
ZNF652 zinc finger protein 652
ZNF8 zinc finger protein 8