vaccinia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in infection, located_in skin, has_material_basis_in Vaccinia virus, which is used as a live vaccine against smallpox. The virus is transmitted_by contact with the vaccination site before it has healed, or transmitted_by fomites that have been contaminated with live virus from the vaccination site. The infection has_symptom rash, has_symptom fever, and has_symptom body aches. (Human Disease Ontology, DOID_3298)
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Genes

293 genes co-occuring with the disease vaccinia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
DUSP3 dual specificity phosphatase 3 2.13466
NTPCR nucleoside-triphosphatase, cancer-related 2.03426
CYB5R3 cytochrome b5 reductase 3 1.94501
ERVW-1 endogenous retrovirus group W, member 1 1.90381
TOP3A topoisomerase (DNA) III alpha 1.88067
CD4 CD4 molecule 1.76411
HLA-B major histocompatibility complex, class I, B 1.74506
VRK2 vaccinia related kinase 2 1.68317
VRK3 vaccinia related kinase 3 1.59921
VRK1 vaccinia related kinase 1 1.56667
LIG1 ligase I, DNA, ATP-dependent 1.52292
RNMT RNA (guanine-7-) methyltransferase 1.51765
RNGTT RNA guanylyltransferase and 5'-phosphatase 1.4149
TOP1 topoisomerase (DNA) I 1.38341
CD58 CD58 molecule 1.34853
HLA-A major histocompatibility complex, class I, A 1.34068
GLB1 galactosidase, beta 1 1.30445
LIG4 ligase IV, DNA, ATP-dependent 1.24428
IL2 interleukin 2 1.23299
CD276 CD276 molecule 1.21478
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.20872
FURIN furin (paired basic amino acid cleaving enzyme) 1.19575
LIG3 ligase III, DNA, ATP-dependent 1.13459
CDSN corneodesmosin 1.1312
AHCY adenosylhomocysteinase 1.10343
KLC2 kinesin light chain 2 1.10006
BANF1 barrier to autointegration factor 1 1.08789
GYPC glycophorin C (Gerbich blood group) 1.01216
LAMP1 lysosomal-associated membrane protein 1 1.00794
DTYMK deoxythymidylate kinase (thymidylate kinase) 1.00035
KLC3 kinesin light chain 3 0.995705
DUSP13 dual specificity phosphatase 13 0.959542
SRSF1 serine/arginine-rich splicing factor 1 0.959542
KLHL2 kelch-like family member 2 0.950769
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.937044
ZNF79 zinc finger protein 79 0.933313
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.886799
VCP valosin containing protein 0.88393
KRAS Kirsten rat sarcoma viral oncogene homolog 0.871643
BDKRB1 bradykinin receptor B1 0.847078
KRT38 keratin 38, type I 0.837656
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 0.827819
KIAA0020 KIAA0020 0.826178
RBMS2 RNA binding motif, single stranded interacting protein 2 0.811001
TWF2 twinfilin actin binding protein 2 0.802385
DMBT1 deleted in malignant brain tumors 1 0.798692
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.798282
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.789262
NCBP2 nuclear cap binding protein subunit 2, 20kDa 0.786394
ICAM1 intercellular adhesion molecule 1 0.785574
TARBP1 TAR (HIV-1) RNA binding protein 1 0.778613
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.770844
VASP vasodilator-stimulated phosphoprotein 0.756971
ZYX zyxin 0.728547
C1R complement component 1, r subcomponent 0.718039
PRODH proline dehydrogenase (oxidase) 1 0.712392
RNASET2 ribonuclease T2 0.706754
RAB24 RAB24, member RAS oncogene family 0.70434
GLRX glutaredoxin (thioltransferase) 0.699919
GFM2 G elongation factor, mitochondrial 2 0.683493
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.681096
PTPRD protein tyrosine phosphatase, receptor type, D 0.673917
RAB2A RAB2A, member RAS oncogene family 0.662784
PTS 6-pyruvoyltetrahydropterin synthase 0.660404
HLA-C major histocompatibility complex, class I, C 0.660008
CD80 CD80 molecule 0.654067
ANK1 ankyrin 1, erythrocytic 0.653671
CD40LG CD40 ligand 0.64577
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.644586
SP6 Sp6 transcription factor 0.640251
RNASEH2A ribonuclease H2, subunit A 0.637889
TLR3 toll-like receptor 3 0.626103
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.625319
DHDH dihydrodiol dehydrogenase (dimeric) 0.616703
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 0.606933
LY75 lymphocyte antigen 75 0.60147
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.598351
SCG5 secretogranin V 0.597961
TACSTD2 tumor-associated calcium signal transducer 2 0.581217
CD79A CD79a molecule, immunoglobulin-associated alpha 0.575772
PFN4 profilin family, member 4 0.573828
MIA2 melanoma inhibitory activity 2 0.571107
EXOSC4 exosome component 4 0.569941
MYD88 myeloid differentiation primary response 88 0.562558
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.561392
IFNA1 interferon, alpha 1 0.558674
CD40 CD40 molecule, TNF receptor superfamily member 5 0.552463
KLK3 kallikrein-related peptidase 3 0.548971
GUK1 guanylate kinase 1 0.547032
C6 complement component 6 0.537731
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.534635
IL4 interleukin 4 0.526904
SH2D3A SH2 domain containing 3A 0.525746
PFN1 profilin 1 0.514186
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.51188
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.51188
DNAH8 dynein, axonemal, heavy chain 8 0.510344
PFN2 profilin 2 0.505739
IL12A interleukin 12A 0.501909
CAPRIN1 cell cycle associated protein 1 0.495411
DNASE2B deoxyribonuclease II beta 0.491978
SERINC5 serine incorporator 5 0.491597
GP2 glycoprotein 2 (zymogen granule membrane) 0.485125
WIPF3 WAS/WASL interacting protein family, member 3 0.479427
PROS2P protein S (beta) pseudogene 0.478668
PES1 pescadillo ribosomal biogenesis factor 1 0.478289
TNF tumor necrosis factor 0.477909
RAB12 RAB12, member RAS oncogene family 0.475255
MGAM maltase-glucoamylase 0.47374
TBRG1 transforming growth factor beta regulator 1 0.465038
HAS1 hyaluronan synthase 1 0.462772
RAB1A RAB1A, member RAS oncogene family 0.460129
NXT1 nuclear transport factor 2-like export factor 1 0.458619
PCSK6 proprotein convertase subtilisin/kexin type 6 0.458241
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.455601
EIF4E eukaryotic translation initiation factor 4E 0.454847
FBL fibrillarin 0.446182
FHOD1 formin homology 2 domain containing 1 0.445429
STRBP spermatid perinuclear RNA binding protein 0.444676
KNTC1 kinetochore associated 1 0.443547
CD300A CD300a molecule 0.441666
CD70 CD70 molecule 0.434148
PRF1 perforin 1 (pore forming protein) 0.431894
PRNT prion protein (testis specific) 0.431144
CSN1S1 casein alpha s1 0.428516
TLR9 toll-like receptor 9 0.42814
TPBG trophoblast glycoprotein 0.427765
MIPEP mitochondrial intermediate peptidase 0.42739
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.427015
PSG5 pregnancy specific beta-1-glycoprotein 5 0.426265
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.424389
STYX serine/threonine/tyrosine interacting protein 0.420641
PARP9 poly (ADP-ribose) polymerase family, member 9 0.417644
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.41465
PEBP4 phosphatidylethanolamine-binding protein 4 0.412779
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.410535
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.407545
GPR1 G protein-coupled receptor 1 0.406798
MLKL mixed lineage kinase domain-like 0.404557
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.404184
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 0.403811
CYTH1 cytohesin 1 0.401572
PENK proenkephalin 0.401199
TTL tubulin tyrosine ligase 0.400826
IRF7 interferon regulatory factor 7 0.400826
HLA-DMB major histocompatibility complex, class II, DM beta 0.396353
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.39598
FBLL1 fibrillarin-like 1 0.391141
IRF3 interferon regulatory factor 3 0.390025
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.390025
UNG uracil-DNA glycosylase 0.390025
MUC1 mucin 1, cell surface associated 0.390025
CDK10 cyclin-dependent kinase 10 0.389281
SEPT4 septin 4 0.383708
MLANA melan-A 0.383708
SLCO1A2 solute carrier organic anion transporter family, member 1A2 0.38111
ACRBP acrosin binding protein 0.377773
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.376661
IL7R interleukin 7 receptor 0.374809
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.374068
TRIO trio Rho guanine nucleotide exchange factor 0.372217
PTK2B protein tyrosine kinase 2 beta 0.371477
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.369258
RAB1B RAB1B, member RAS oncogene family 0.368888
SAG S-antigen; retina and pineal gland (arrestin) 0.362978
SDPR serum deprivation response 0.362609
MAVS mitochondrial antiviral signaling protein 0.360764
DUSP6 dual specificity phosphatase 6 0.359657
GRB2 growth factor receptor-bound protein 2 0.358183
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.358183
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.356341
IFNA10 interferon, alpha 10 0.356341
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.347144
ACTA1 actin, alpha 1, skeletal muscle 0.347144
NFYB nuclear transcription factor Y, beta 0.346409
NCK1 NCK adaptor protein 1 0.342372
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.342006
TMPRSS11D transmembrane protease, serine 11D 0.336144
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.335778
MAPK1 mitogen-activated protein kinase 1 0.333949
ITSN1 intersectin 1 (SH3 domain protein) 0.333583
C12ORF57 chromosome 12 open reading frame 57 0.332852
HLA-E major histocompatibility complex, class I, E 0.3292
CDC42 cell division cycle 42 0.32373
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.319363
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.318635
LIPA lipase A, lysosomal acid, cholesterol esterase 0.313189
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.310652
BTG3 BTG family, member 3 0.308118
EIF4B eukaryotic translation initiation factor 4B 0.308118
TEAD2 TEA domain family member 2 0.307395
PDGFB platelet-derived growth factor beta polypeptide 0.307033
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.304503
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.303781
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.303059
DSTN destrin (actin depolymerizing factor) 0.302337
CAV2 caveolin 2 0.300533
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.297291
POU2F1 POU class 2 homeobox 1 0.297291
CLMP CXADR-like membrane protein 0.292975
TP53 tumor protein p53 0.292616
RAP2A RAP2A, member of RAS oncogene family 0.290821
ATG3 autophagy related 3 0.286519
TEN1 TEN1 CST complex subunit 0.285802
FRK fyn-related Src family tyrosine kinase 0.285086
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.282225
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.281868
MTUS1 microtubule associated tumor suppressor 1 0.281153
TSPO translocator protein (18kDa) 0.280796
LIMK2 LIM domain kinase 2 0.280082
CD27 CD27 molecule 0.279724
ADGRB1 adhesion G protein-coupled receptor B1 0.279011
CXCL9 chemokine (C-X-C motif) ligand 9 0.275445
TLR8 toll-like receptor 8 0.274376
AK6 adenylate kinase 6 0.269043
PTGDR prostaglandin D2 receptor (DP) 0.267622
THY1 Thy-1 cell surface antigen 0.259477
NTSR1 neurotensin receptor 1 (high affinity) 0.25877
STAB1 stabilin 1 0.254536
WIPF2 WAS/WASL interacting protein family, member 2 0.247852
UCKL1 uridine-cytidine kinase 1-like 1 0.246448
PMEL premelanosome protein 0.245747
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.243995
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.243645
EPCAM epithelial cell adhesion molecule 0.243645
UCK1 uridine-cytidine kinase 1 0.240148
NFYA nuclear transcription factor Y, alpha 0.235268
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.234573
LRRC38 leucine rich repeat containing 38 0.234573
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.234225
HLTF helicase-like transcription factor 0.231102
IL1B interleukin 1, beta 0.228679
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.224196
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 0.222822
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 0.222136
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.220766
BCL6B B-cell CLL/lymphoma 6, member B 0.220766
MT-ATP8 ATP synthase F0 subunit 8 0.220081
CIITA class II, major histocompatibility complex, transactivator 0.216672
WAS Wiskott-Aldrich syndrome 0.215992
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.214297
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.213621
CD86 CD86 molecule 0.208579
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.207912
RAP1B RAP1B, member of RAS oncogene family 0.20658
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.204593
TAT tyrosine aminotransferase 0.203933
STAT1 signal transducer and activator of transcription 1, 91kDa 0.203275
APOPT1 apoptogenic 1, mitochondrial 0.201962
MX1 MX dynamin-like GTPase 1 0.200331
NELFCD negative elongation factor complex member C/D 0.199356
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.198709
COIL coilin 0.198709
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.195183
KSR1 kinase suppressor of ras 1 0.195183
UCK2 uridine-cytidine kinase 2 0.195183
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.190168
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.189244
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.186811
TMEM245 transmembrane protein 245 0.18591
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.185313
CAMP cathelicidin antimicrobial peptide 0.180084
B2M beta-2-microglobulin 0.177851
ENGASE endo-beta-N-acetylglucosaminidase 0.176757
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.176757
DUSP5 dual specificity phosphatase 5 0.175947
PCDH8 protocadherin 8 0.175679
PDS5B PDS5 cohesin associated factor B 0.175411
LPO lactoperoxidase 0.174881
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.174093
IL18R1 interleukin 18 receptor 1 0.170789
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.170789
ERF Ets2 repressor factor 0.170299
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.170054
PPARD peroxisome proliferator-activated receptor delta 0.169812
GAS1 growth arrest-specific 1 0.168617
ARHGAP18 Rho GTPase activating protein 18 0.167682
ACPP acid phosphatase, prostate 0.166095
PCSK2 proprotein convertase subtilisin/kexin type 2 0.164571
AXL AXL receptor tyrosine kinase 0.164149
MBP myelin basic protein 0.163523
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.163111
EPS15 epidermal growth factor receptor pathway substrate 15 0.162908
CSPG4 chondroitin sulfate proteoglycan 4 0.162707
SFTPD surfactant protein D 0.162306
OCM2 oncomodulin 2 0.161912
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.161716
LAMP2 lysosomal-associated membrane protein 2 0.161716
WRAP73 WD repeat containing, antisense to TP73 0.160387
SOS1 son of sevenless homolog 1 (Drosophila) 0.159124
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 0.159124
TOP2B topoisomerase (DNA) II beta 180kDa 0.158434
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.158266