vacuolar acidification Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion. (Gene Ontology, GO_0007035)
External Link http://amigo.geneontology.org/amigo/term/GO:0007035
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Genes

32 genes participating in the vacuolar acidification biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN5 ceroid-lipofuscinosis, neuronal 5
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
DMXL1 Dmx-like 1
DMXL2 Dmx-like 2
GRN granulin
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
PPT1 palmitoyl-protein thioesterase 1
RNASEK ribonuclease, RNase K
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TMEM9 transmembrane protein 9
VMA12 vacuolar ATPase assembly factor VMA12
VMA22 vacuolar ATPase assembly factor VMA22