vacuolar lumen Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description The volume enclosed within the vacuolar membrane. (Gene Ontology, GO_0005775)
External Link http://amigo.geneontology.org/amigo/term/GO:0005775
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Genes

162 proteins localized to the vacuolar lumen cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
ACAN aggrecan
ACLY ATP citrate lyase
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
AGA aspartylglucosaminidase
AGRN agrin
ANXA2 annexin A2
APOB apolipoprotein B
ARG1 arginase 1
ARHGAP45 Rho GTPase activating protein 45
ARSA arylsulfatase A
ARSB arylsulfatase B
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP13A2 ATPase type 13A2
AZU1 azurocidin 1
BCAN brevican
BGN biglycan
BPI bactericidal/permeability-increasing protein
C3 complement component 3
C6ORF120 chromosome 6 open reading frame 120
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEL carboxyl ester lipase
CHID1 chitinase domain containing 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CREG1 cellular repressor of E1A-stimulated genes 1
CSF3 colony stimulating factor 3 (granulocyte)
CSPG4 chondroitin sulfate proteoglycan 4
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTSA cathepsin A
CTSC cathepsin C
CTSD cathepsin D
CTSF cathepsin F
CTSG cathepsin G
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYB5R3 cytochrome b5 reductase 3
DCN decorin
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPP7 dipeptidyl-peptidase 7
DSN1 DSN1, MIS12 kinetochore complex component
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
ELANE elastase, neutrophil expressed
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAF2 Fas associated factor family member 2
FMOD fibromodulin
FRK fyn-related Src family tyrosine kinase
FTL ferritin, light polypeptide
FUCA1 fucosidase, alpha-L- 1, tissue
FUCA2 fucosidase, alpha-L- 2, plasma
GAA glucosidase, alpha; acid
GALC galactosylceramidase
GALNS galactosamine (N-acetyl)-6-sulfatase
GBA glucosidase, beta, acid
GBAP1 glucosidase, beta, acid pseudogene 1
GCA grancalcin, EF-hand calcium binding protein
GDI2 GDP dissociation inhibitor 2
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GIF gastric intrinsic factor (vitamin B synthesis)
GLA galactosidase, alpha
GLB1 galactosidase, beta 1
GM2A GM2 ganglioside activator
GNS glucosamine (N-acetyl)-6-sulfatase
GPC1 glypican 1
GPC2 glypican 2
GPC3 glypican 3
GPC4 glypican 4
GPC5 glypican 5
GPC6 glypican 6
GRN granulin
GUSB glucuronidase, beta
GYG1 glycogenin 1
HEBP2 heme binding protein 2
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HPSE heparanase
HRNR hornerin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA8 heat shock 70kDa protein 8
HSPG2 heparan sulfate proteoglycan 2
HYAL1 hyaluronoglucosaminidase 1
IDS iduronate 2-sulfatase
IDUA iduronidase, alpha-L-
IFI30 interferon, gamma-inducible protein 30
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IST1 increased sodium tolerance 1 homolog (yeast)
KERA keratocan
LAMP2 lysosomal-associated membrane protein 2
LGALS13 lectin, galactoside-binding, soluble, 13
LGMN legumain
LUM lumican
LYZ lysozyme
MAN2B1 mannosidase, alpha, class 2B, member 1
MAN2B2 mannosidase, alpha, class 2B, member 2
MANBA mannosidase, beta A, lysosomal
MAPK1 mitogen-activated protein kinase 1
MNDA myeloid cell nuclear differentiation antigen
MPO myeloperoxidase
NAAA N-acylethanolamine acid amidase
NAGLU N-acetylglucosaminidase, alpha
NAPRT nicotinate phosphoribosyltransferase
NCAN neurocan
NEU1 sialidase 1 (lysosomal sialidase)
NEU4 sialidase 4
NHLRC3 NHL repeat containing 3
NPC2 Niemann-Pick disease, type C2
OGN osteoglycin
OMD osteomodulin
ORM2 orosomucoid 2
PA2G4 proliferation-associated 2G4, 38kDa
PADI2 peptidyl arginine deiminase, type II
PLD3 phospholipase D family, member 3
PPT1 palmitoyl-protein thioesterase 1
PPT2 palmitoyl-protein thioesterase 2
PRDX6 peroxiredoxin 6
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKCD protein kinase C, delta
PRSS2 protease, serine, 2 (trypsin 2)
PRSS57 protease, serine, 57
PRSS8 protease, serine, 8
PRTN3 proteinase 3
PSAP prosaposin
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTGES2 prostaglandin E synthase 2
PYCARD PYD and CARD domain containing
PYGB phosphorylase, glycogen; brain
RETN resistin
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNASET2 ribonuclease T2
S100A7 S100 calcium binding protein A7
SCARB2 scavenger receptor class B, member 2
SDC1 syndecan 1
SDC2 syndecan 2
SDC3 syndecan 3
SDC4 syndecan 4
SDCBP syndecan binding protein (syntenin)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SGSH N-sulfoglucosamine sulfohydrolase
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
STK11IP serine/threonine kinase 11 interacting protein
TADA2A transcriptional adaptor 2A
TCN2 transcobalamin II
TOLLIP toll interacting protein
TPP1 tripeptidyl peptidase I
TRAPPC1 trafficking protein particle complex 1
TTR transthyretin
TUBB2A tubulin, beta 2A class IIa
TUBB4B tubulin, beta 4B class IVb
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UNC13D unc-13 homolog D (C. elegans)
VCAN versican
VCP valosin containing protein