vacuole Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. (Gene Ontology, GO_0005773)
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Genes

25 genes co-occuring with the biological term vacuole in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
BAK1 BCL2-antagonist/killer 1
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDC42 cell division cycle 42
CLN3 ceroid-lipofuscinosis, neuronal 3
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HTN3 histatin 3
IGF1 insulin-like growth factor 1 (somatomedin C)
MAN2B1 mannosidase, alpha, class 2B, member 1
MIR210 microRNA 210
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RAB14 RAB14, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RHOA ras homolog family member A
SPATA18 spermatogenesis associated 18
SULF1 sulfatase 1
SULF2 sulfatase 2
TLR8 toll-like receptor 8
TP53 tumor protein p53
VAMP7 vesicle-associated membrane protein 7
VEGFA vascular endothelial growth factor A
VMP1 vacuole membrane protein 1
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)