| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the valdecoxib-6403 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADCY10 | adenylate cyclase 10 (soluble) |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| APOA1 | apolipoprotein A-I |
| ARHGAP24 | Rho GTPase activating protein 24 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BCL3 | B-cell CLL/lymphoma 3 |
| CA14 | carbonic anhydrase XIV |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CDK19 | cyclin-dependent kinase 19 |
| CIB2 | calcium and integrin binding family member 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DAPK1 | death-associated protein kinase 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EGFL7 | EGF-like-domain, multiple 7 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GK | glycerol kinase |
| GLRA2 | glycine receptor, alpha 2 |
| GNAS | GNAS complex locus |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HFE | hemochromatosis |
| HIST1H4G | histone cluster 1, H4g |
| HLF | hepatic leukemia factor |
| HOXA1 | homeobox A1 |
| HRH1 | histamine receptor H1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HSF4 | heat shock transcription factor 4 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL1RAP | interleukin 1 receptor accessory protein |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| KCNIP1 | Kv channel interacting protein 1 |
| LMNA | lamin A/C |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRC1 | leucine rich repeat containing 1 |
| MALL | mal, T-cell differentiation protein-like |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MTMR3 | myotubularin related protein 3 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO7A | myosin VIIA |
| NCALD | neurocalcin delta |
| NELL2 | NEL-like 2 (chicken) |
| NOX3 | NADPH oxidase 3 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PCDH7 | protocadherin 7 |
| PCDHB3 | protocadherin beta 3 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLEK | pleckstrin |
| PTMS | parathymosin |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RPL10L | ribosomal protein L10-like |
| RPL7 | ribosomal protein L7 |
| SAFB | scaffold attachment factor B |
| SAFB2 | scaffold attachment factor B2 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLN | sarcolipin |
| SMAD6 | SMAD family member 6 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNJ2 | synaptojanin 2 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM3 | tripartite motif containing 3 |
| UBXN1 | UBX domain protein 1 |
| VIL1 | villin 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALOX12 | arachidonate 12-lipoxygenase |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CFH | complement factor H |
| CLCA3P | chloride channel accessory 3, pseudogene |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL15A1 | collagen, type XV, alpha 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CSDC2 | cold shock domain containing C2, RNA binding |
| CSF1R | colony stimulating factor 1 receptor |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DYSF | dysferlin |
| EN2 | engrailed homeobox 2 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EPX | eosinophil peroxidase |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM76A | family with sequence similarity 76, member A |
| FGF4 | fibroblast growth factor 4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPR143 | G protein-coupled receptor 143 |
| GPR15 | G protein-coupled receptor 15 |
| GRM2 | glutamate receptor, metabotropic 2 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H3I | histone cluster 1, H3i |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HOXC5 | homeobox C5 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL11RA | interleukin 11 receptor, alpha |
| IL36RN | interleukin 36 receptor antagonist |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA1456 | KIAA1456 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LPXN | leupaxin |
| LTC4S | leukotriene C4 synthase |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| NPPA | natriuretic peptide A |
| NTN1 | netrin 1 |
| PCDHA5 | protocadherin alpha 5 |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLAC4 | placenta-specific 4 |
| POF1B | premature ovarian failure, 1B |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PQLC2 | PQ loop repeat containing 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRLH | prolactin releasing hormone |
| PRO2964 | uncharacterized protein PRO2964 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PURG | purine-rich element binding protein G |
| QPCT | glutaminyl-peptide cyclotransferase |
| RASAL2 | RAS protein activator like 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RELN | reelin |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SLC35G2 | solute carrier family 35, member G2 |
| SLC5A12 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 |
| STAC | SH3 and cysteine rich domain |
| STXBP5L | syntaxin binding protein 5-like |
| SYT2 | synaptotagmin II |
| TBX3 | T-box 3 |
| TCTN2 | tectonic family member 2 |
| TMC5 | transmembrane channel-like 5 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TUBA3C | tubulin, alpha 3c |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR33 | WD repeat domain 33 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF358 | zinc finger protein 358 |
