validated Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

187 genes co-occuring with the biological term validated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACAD9 acyl-CoA dehydrogenase family, member 9
ACSS2 acyl-CoA synthetase short-chain family member 2
ADRB2 adrenoceptor beta 2, surface
AGO2 argonaute RISC catalytic component 2
AICDA activation-induced cytidine deaminase
ANK1 ankyrin 1, erythrocytic
APC adenomatous polyposis coli
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCAS3 breast carcinoma amplified sequence 3
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMTA1 calmodulin binding transcription activator 1
CCK cholecystokinin
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCNY cyclin Y
CD163 CD163 molecule
CDA cytidine deaminase
CDK2 cyclin-dependent kinase 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CELF4 CUGBP, Elav-like family member 4
CERKL ceramide kinase-like
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COL1A2 collagen, type I, alpha 2
COTL1 coactosin-like F-actin binding protein 1
CRH corticotropin releasing hormone
CRY1 cryptochrome circadian clock 1
CSNK1E casein kinase 1, epsilon
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAAM2 dishevelled associated activator of morphogenesis 2
DDIT4L DNA-damage-inducible transcript 4-like
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DLG4 discs, large homolog 4 (Drosophila)
DSPP dentin sialophosphoprotein
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
EVA1C eva-1 homolog C (C. elegans)
FAM129A family with sequence similarity 129, member A
FAM71F2 family with sequence similarity 71, member F2
FBLN2 fibulin 2
FGF2 fibroblast growth factor 2 (basic)
FLT4 fms-related tyrosine kinase 4
FMN2 formin 2
FMNL3 formin-like 3
FRS2 fibroblast growth factor receptor substrate 2
FXN frataxin
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAS GNAS complex locus
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GUCY2C guanylate cyclase 2C
GUSB glucuronidase, beta
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HMOX1 heme oxygenase 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPR heterogeneous nuclear ribonucleoprotein R
HOXA13 homeobox A13
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTRA1 HtrA serine peptidase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHV3-21 immunoglobulin heavy variable 3-21
IL4 interleukin 4
IRX4 iroquois homeobox 4
ISCU iron-sulfur cluster assembly enzyme
KDM2B lysine (K)-specific demethylase 2B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA1524 KIAA1524
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRAS Kirsten rat sarcoma viral oncogene homolog
LCN2 lipocalin 2
LCT lactase
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
LIMD1 LIM domains containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK7 mitogen-activated protein kinase 7
MBD1 methyl-CpG binding domain protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEF2C myocyte enhancer factor 2C
MEP1B meprin A, beta
MIR100 microRNA 100
MIR10B microRNA 10b
MIR128-1 microRNA 128-1
MIR141 microRNA 141
MIR143 microRNA 143
MIR145 microRNA 145
MIR146A microRNA 146a
MIR155 microRNA 155
MIR16-1 microRNA 16-1
MIR214 microRNA 214
MIR335 microRNA 335
MIR34C microRNA 34c
MKI67 marker of proliferation Ki-67
MMP3 matrix metallopeptidase 3
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MT1G metallothionein 1G
MTTP microsomal triglyceride transfer protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAGK N-acetylglucosamine kinase
NEK9 NIMA-related kinase 9
NPM2 nucleophosmin/nucleoplasmin 2
NTSR1 neurotensin receptor 1 (high affinity)
PAX6 paired box 6
PCBP2 poly(rC) binding protein 2
PCGF2 polycomb group ring finger 2
PCID2 PCI domain containing 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PGK1 phosphoglycerate kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCD1 phospholipase C, delta 1
PLCE1 phospholipase C, epsilon 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PMP22 peripheral myelin protein 22
POLG polymerase (DNA directed), gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCZ protein kinase C, zeta
PRNP prion protein
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAD51 RAD51 recombinase
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOV ras homolog family member V
RINT1 RAD50 interactor 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RYK receptor-like tyrosine kinase
S100A7 S100 calcium binding protein A7
SAMHD1 SAM domain and HD domain 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SPRY4 sprouty homolog 4 (Drosophila)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRRT serrate, RNA effector molecule
SRXN1 sulfiredoxin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TLR2 toll-like receptor 2
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TST thiosulfate sulfurtransferase (rhodanese)
UMOD uromodulin