valinomycin-5906 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the valinomycin-5906 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADGRA2 adhesion G protein-coupled receptor A2
AMOTL2 angiomotin like 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF3 activating transcription factor 3
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC87 coiled-coil domain containing 87
CD82 CD82 molecule
CENPO centromere protein O
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLGN calmegin
CYHR1 cysteine/histidine-rich 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DOCK6 dedicator of cytokinesis 6
DOK4 docking protein 4
DRD1 dopamine receptor D1
DTNA dystrobrevin, alpha
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM134B family with sequence similarity 134, member B
FHL1 four and a half LIM domains 1
FRAS1 Fraser extracellular matrix complex subunit 1
FRMD4A FERM domain containing 4A
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRB10 growth factor receptor-bound protein 10
GSTA3 glutathione S-transferase alpha 3
GTPBP2 GTP binding protein 2
HIST1H2BN histone cluster 1, H2bn
HLF hepatic leukemia factor
HOXA11 homeobox A11
ICAM1 intercellular adhesion molecule 1
INHBE inhibin, beta E
KIF21B kinesin family member 21B
KLF2 Kruppel-like factor 2
LAT2 linker for activation of T cells family, member 2
LOXL3 lysyl oxidase-like 3
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP2 latent transforming growth factor beta binding protein 2
MBNL2 muscleblind-like splicing regulator 2
MED16 mediator complex subunit 16
MEF2D myocyte enhancer factor 2D
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPL41 mitochondrial ribosomal protein L41
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAV2 neuron navigator 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NSUN6 NOP2/Sun domain family, member 6
NUPR1 nuclear protein, transcriptional regulator, 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRKCA protein kinase C, alpha
PSCA prostate stem cell antigen
RAD52 RAD52 homolog (S. cerevisiae)
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUSC2 RUN and SH3 domain containing 2
RYR1 ryanodine receptor 1 (skeletal)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SENP5 SUMO1/sentrin specific peptidase 5
SFTPC surfactant protein C
SIRT5 sirtuin 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG5 SMG5 nonsense mediated mRNA decay factor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STK24 serine/threonine kinase 24
STX7 syntaxin 7
TBX3 T-box 3
TFF2 trefoil factor 2
TLE2 transducin-like enhancer of split 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIB3 tribbles pseudokinase 3
TSPAN9 tetraspanin 9
UCN urocortin
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WAS Wiskott-Aldrich syndrome
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF358 zinc finger protein 358
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADGRG2 adhesion G protein-coupled receptor G2
AHDC1 AT hook, DNA binding motif, containing 1
AVPR1B arginine vasopressin receptor 1B
BCL2A1 BCL2-related protein A1
C11ORF1 chromosome 11 open reading frame 1
C5AR2 complement component 5a receptor 2
CABP5 calcium binding protein 5
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CCKBR cholecystokinin B receptor
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CETN1 centrin, EF-hand protein, 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCA1 chloride channel accessory 1
CNTN1 contactin 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPLX2 complexin 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXXC4 CXXC finger protein 4
DEPDC5 DEP domain containing 5
DGAT1 diacylglycerol O-acyltransferase 1
DUOX2 dual oxidase 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ENOX1 ecto-NOX disulfide-thiol exchanger 1
F2R coagulation factor II (thrombin) receptor
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF13 fibroblast growth factor 13
FGR FGR proto-oncogene, Src family tyrosine kinase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GIPR gastric inhibitory polypeptide receptor
GMPR guanosine monophosphate reductase
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HOXB2 homeobox B2
HOXC5 homeobox C5
HSPA2 heat shock 70kDa protein 2
IDI2-AS1 IDI2 antisense RNA 1
IFNA16 interferon, alpha 16
IFT54 intraflagellar transport 54
IL12RB2 interleukin 12 receptor, beta 2
KCNIP2 Kv channel interacting protein 2
KCNK10 potassium channel, two pore domain subfamily K, member 10
KLHL29 kelch-like family member 29
KLK5 kallikrein-related peptidase 5
LECT2 leukocyte cell-derived chemotaxin 2
LENEP lens epithelial protein
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00260 long intergenic non-protein coding RNA 260
LRP4 low density lipoprotein receptor-related protein 4
MALL mal, T-cell differentiation protein-like
MAOB monoamine oxidase B
MCTP1 multiple C2 domains, transmembrane 1
MEFV Mediterranean fever
MEGF6 multiple EGF-like-domains 6
MMRN2 multimerin 2
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
NANOG Nanog homeobox
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
OSBP2 oxysterol binding protein 2
PCDH12 protocadherin 12
PGR progesterone receptor
PNMAL1 paraneoplastic Ma antigen family-like 1
RAB40AL RAB40A, member RAS oncogene family-like
RAB40C RAB40C, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RIBC2 RIB43A domain with coiled-coils 2
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
S1PR2 sphingosine-1-phosphate receptor 2
SAMD9 sterile alpha motif domain containing 9
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SH2D2A SH2 domain containing 2A
SLAMF7 SLAM family member 7
SLFN12 schlafen family member 12
SOCS7 suppressor of cytokine signaling 7
SPINK5 serine peptidase inhibitor, Kazal type 5
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SULT4A1 sulfotransferase family 4A, member 1
TBL1Y transducin (beta)-like 1, Y-linked
TM4SF4 transmembrane 4 L six family member 4
TMPRSS5 transmembrane protease, serine 5
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TYRP1 tyrosinase-related protein 1
XCR1 chemokine (C motif) receptor 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF205 zinc finger protein 205
ZNF76 zinc finger protein 76