valinomycin-5911 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valinomycin-5911 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
AIM1L absent in melanoma 1-like
AMIGO2 adhesion molecule with Ig-like domain 2
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
BBC3 BCL2 binding component 3
BMP2 bone morphogenetic protein 2
BTG2 BTG family, member 2
C1ORF116 chromosome 1 open reading frame 116
CALD1 caldesmon 1
CARS cysteinyl-tRNA synthetase
CBS cystathionine-beta-synthase
CCDC106 coiled-coil domain containing 106
CDC5L cell division cycle 5-like
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTH cystathionine gamma-lyase
CTSZ cathepsin Z
CXCL2 chemokine (C-X-C motif) ligand 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCTN1 dynactin 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
EFNA3 ephrin-A3
ERN2 endoplasmic reticulum to nucleus signaling 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM129A family with sequence similarity 129, member A
FGF2 fibroblast growth factor 2 (basic)
FOXO4 forkhead box O4
FYN FYN proto-oncogene, Src family tyrosine kinase
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
HSF2BP heat shock transcription factor 2 binding protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL11 interleukin 11
IL33R interleukin 33 receptor
IL36RN interleukin 36 receptor antagonist
INHBA inhibin, beta A
INHBE inhibin, beta E
JUNB jun B proto-oncogene
KDM7A lysine (K)-specific demethylase 7A
KLF4 Kruppel-like factor 4 (gut)
KLHL24 kelch-like family member 24
KRT16 keratin 16, type I
KRT34 keratin 34, type I
LARP6 La ribonucleoprotein domain family, member 6
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOCS3 molybdenum cofactor synthesis 3
NNMT nicotinamide N-methyltransferase
NUPR1 nuclear protein, transcriptional regulator, 1
OGFR opioid growth factor receptor
PADI2 peptidyl arginine deiminase, type II
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE4D phosphodiesterase 4D, cAMP-specific
PHGDH phosphoglycerate dehydrogenase
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCH1 phospholipase C, eta 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAT1 phosphoserine aminotransferase 1
PSPH phosphoserine phosphatase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RAB2A RAB2A, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RUFY3 RUN and FYVE domain containing 3
S100P S100 calcium binding protein P
SAYSD1 SAYSVFN motif domain containing 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SGK2 serum/glucocorticoid regulated kinase 2
SH2D3A SH2 domain containing 3A
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STC2 stanniocalcin 2
THBD thrombomodulin
TJP3 tight junction protein 3
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAIP TRAF interacting protein
TRIB3 tribbles pseudokinase 3
WARS tryptophanyl-tRNA synthetase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB7A zinc finger and BTB domain containing 7A
ZNF268 zinc finger protein 268
ZNF391 zinc finger protein 391
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM15 ADAM metallopeptidase domain 15
ADRB2 adrenoceptor beta 2, surface
ASAP1-IT1 ASAP1 intronic transcript 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCCIP BRCA2 and CDKN1A interacting protein
BCL9 B-cell CLL/lymphoma 9
BTBD18 BTB (POZ) domain containing 18
BTN3A2 butyrophilin, subfamily 3, member A2
C16ORF59 chromosome 16 open reading frame 59
C1S complement component 1, s subcomponent
C7ORF43 chromosome 7 open reading frame 43
CA9 carbonic anhydrase IX
CBX8 chromobox homolog 8
CCNE2 cyclin E2
CD3EAP CD3e molecule, epsilon associated protein
CD83 CD83 molecule
CDT1 chromatin licensing and DNA replication factor 1
CEL carboxyl ester lipase
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CPNE7 copine VII
CPOX coproporphyrinogen oxidase
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DIO3 deiodinase, iodothyronine, type III
DIXDC1 DIX domain containing 1
DNAH17 dynein, axonemal, heavy chain 17
EHF ets homologous factor
EN2 engrailed homeobox 2
EPHB3 EPH receptor B3
EXO5 exonuclease 5
FAM120C family with sequence similarity 120C
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGL1 fibrinogen-like 1
FLJ11710 uncharacterized protein FLJ11710
GBP2 guanylate binding protein 2, interferon-inducible
GJC1 gap junction protein, gamma 1, 45kDa
GK2 glycerol kinase 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HIST1H4E histone cluster 1, H4e
HOOK1 hook microtubule-tethering protein 1
HOXA6 homeobox A6
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
IL17RB interleukin 17 receptor B
KLHL36 kelch-like family member 36
KRT4 keratin 4, type II
LIPG lipase, endothelial
LYPD3 LY6/PLAUR domain containing 3
MAMLD1 mastermind-like domain containing 1
MANEA mannosidase, endo-alpha
MN1 meningioma (disrupted in balanced translocation) 1
MRPL44 mitochondrial ribosomal protein L44
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTCL1 microtubule crosslinking factor 1
MXRA8 matrix-remodelling associated 8
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAP1L2 nucleosome assembly protein 1-like 2
NCALD neurocalcin delta
NDP Norrie disease (pseudoglioma)
NDRG4 NDRG family member 4
NOL12 nucleolar protein 12
NRTN neurturin
ODF2 outer dense fiber of sperm tails 2
OGDHL oxoglutarate dehydrogenase-like
ORC1 origin recognition complex, subunit 1
OSBP2 oxysterol binding protein 2
PALMD palmdelphin
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDZK1 PDZ domain containing 1
PLK2 polo-like kinase 2
RAB3A RAB3A, member RAS oncogene family
RANBP6 RAN binding protein 6
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RPA4 replication protein A4, 30kDa
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHROOM2 shroom family member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SOX9 SRY (sex determining region Y)-box 9
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
THEM6 thioesterase superfamily member 6
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
TMEM74B transmembrane protein 74B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VNN2 vanin 2
WDR25 WD repeat domain 25
WNT10B wingless-type MMTV integration site family, member 10B