valproic acid-1047 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the valproic acid-1047 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD6 abhydrolase domain containing 6
ADD3 adducin 3 (gamma)
ARMCX1 armadillo repeat containing, X-linked 1
BBX bobby sox homolog (Drosophila)
BCORL1 BCL6 corepressor-like 1
BEX4 brain expressed, X-linked 4
BMP7 bone morphogenetic protein 7
BTG3 BTG family, member 3
BTN2A2 butyrophilin, subfamily 2, member A2
C2ORF49 chromosome 2 open reading frame 49
CCDC88A coiled-coil domain containing 88A
CORO1A coronin, actin binding protein, 1A
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CSRP2 cysteine and glycine-rich protein 2
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EFNB3 ephrin-B3
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELOVL4 ELOVL fatty acid elongase 4
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADS3 fatty acid desaturase 3
FAM114A1 family with sequence similarity 114, member A1
FBXO11 F-box protein 11
FHL1 four and a half LIM domains 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD1 frizzled class receptor 1
GLRX glutaredoxin (thioltransferase)
GRB10 growth factor receptor-bound protein 10
HLA-F major histocompatibility complex, class I, F
IL1RAP interleukin 1 receptor accessory protein
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDSR 3-ketodihydrosphingosine reductase
KIAA0513 KIAA0513
KIAA0586 KIAA0586
KIAA0895 KIAA0895
KIF5C kinesin family member 5C
KLHL23 kelch-like family member 23
KLHL24 kelch-like family member 24
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LTBP1 latent transforming growth factor beta binding protein 1
LYPD3 LY6/PLAUR domain containing 3
MAGEH1 melanoma antigen family H1
MAPT microtubule-associated protein tau
METTL7A methyltransferase like 7A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MNS1 meiosis-specific nuclear structural 1
MORC4 MORC family CW-type zinc finger 4
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
NDRG4 NDRG family member 4
NKX3-2 NK3 homeobox 2
OGG1 8-oxoguanine DNA glycosylase
OPTN optineurin
PEX1 peroxisomal biogenesis factor 1
PGM1 phosphoglucomutase 1
PHF21A PHD finger protein 21A
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLA2G10 phospholipase A2, group X
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRKCH protein kinase C, eta
PRPH peripherin
PTCH1 patched 1
PTRF polymerase I and transcript release factor
RAB29 RAB29, member RAS oncogene family
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RTN2 reticulon 2
SALL2 spalt-like transcription factor 2
SFXN3 sideroflexin 3
SH2B2 SH2B adaptor protein 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC31A1 solute carrier family 31 (copper transporter), member 1
SMAD6 SMAD family member 6
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNN stannin
SSBP3 single stranded DNA binding protein 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX2 syntaxin 2
STXBP1 syntaxin binding protein 1
SYBU syntabulin (syntaxin-interacting)
TRIM2 tripartite motif containing 2
TSPAN5 tetraspanin 5
TTC33 tetratricopeptide repeat domain 33
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA4A tubulin, alpha 4a
UBE2L6 ubiquitin-conjugating enzyme E2L 6
ULBP2 UL16 binding protein 2
UST uronyl-2-sulfotransferase
WASF1 WAS protein family, member 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
YPEL5 yippee-like 5 (Drosophila)
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ANAPC10 anaphase promoting complex subunit 10
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BANP BTG3 associated nuclear protein
BOLA1 bolA family member 1
C5 complement component 5
CCDC101 coiled-coil domain containing 101
CDT1 chromatin licensing and DNA replication factor 1
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
DDB1 damage-specific DNA binding protein 1, 127kDa
DDRGK1 DDRGK domain containing 1
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EFNA1 ephrin-A1
ESRP2 epithelial splicing regulatory protein 2
FANCL Fanconi anemia, complementation group L
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GLMN glomulin, FKBP associated protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2I general transcription factor IIi
GTPBP8 GTP-binding protein 8 (putative)
HIRIP3 HIRA interacting protein 3
HIST1H2BI histone cluster 1, H2bi
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
KAT2A K(lysine) acetyltransferase 2A
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIPT1 lipoyltransferase 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP3 low density lipoprotein receptor-related protein 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEPCE methylphosphate capping enzyme
METTL18 methyltransferase like 18
MSL2 male-specific lethal 2 homolog (Drosophila)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCSTN nicastrin
NHEJ1 nonhomologous end-joining factor 1
NMU neuromedin U
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUBP1 nucleotide binding protein 1
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PHF11 PHD finger protein 11
PHLDA3 pleckstrin homology-like domain, family A, member 3
PISD phosphatidylserine decarboxylase
PLK2 polo-like kinase 2
PMF1 polyamine-modulated factor 1
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRMT1 protein arginine methyltransferase 1
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM22 RNA binding motif protein 22
RND3 Rho family GTPase 3
SFMBT1 Scm-like with four mbt domains 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLTM SAFB-like, transcription modulator
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SNRPF small nuclear ribonucleoprotein polypeptide F
SPAG1 sperm associated antigen 1
SPAG7 sperm associated antigen 7
SPIN1 spindlin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYTL2 synaptotagmin-like 2
TARBP2 TAR (HIV-1) RNA binding protein 2
TDP2 tyrosyl-DNA phosphodiesterase 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM185B transmembrane protein 185B
TMEM223 transmembrane protein 223
TMEM39B transmembrane protein 39B
TPTE transmembrane phosphatase with tensin homology
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN15 tetraspanin 15
TTC17 tetratricopeptide repeat domain 17
UBXN8 UBX domain protein 8
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VRK2 vaccinia related kinase 2
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZZZ3 zinc finger, ZZ-type containing 3
Funding