valproic acid-1155 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the valproic acid-1155 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACOX2 acyl-CoA oxidase 2, branched chain
ADA adenosine deaminase
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANKRD6 ankyrin repeat domain 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARNTL aryl hydrocarbon receptor nuclear translocator-like
CD59 CD59 molecule, complement regulatory protein
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DOCK4 dedicator of cytokinesis 4
ECI2 enoyl-CoA delta isomerase 2
EML3 echinoderm microtubule associated protein like 3
ERO1LB ERO1-like beta (S. cerevisiae)
F11R F11 receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLNB filamin B, beta
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GAREM GRB2 associated, regulator of MAPK1
GAS2L1 growth arrest-specific 2 like 1
GDAP1 ganglioside induced differentiation associated protein 1
GLP1R glucagon-like peptide 1 receptor
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HLA-DMA major histocompatibility complex, class II, DM alpha
IFNA14 interferon, alpha 14
IL11RA interleukin 11 receptor, alpha
IL18RAP interleukin 18 receptor accessory protein
IL2 interleukin 2
ITGA7 integrin, alpha 7
LRP2 low density lipoprotein receptor-related protein 2
LY6E lymphocyte antigen 6 complex, locus E
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MARCKS myristoylated alanine-rich protein kinase C substrate
MECOM MDS1 and EVI1 complex locus
MKL2 MKL/myocardin-like 2
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MPZL1 myelin protein zero-like 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTUS1 microtubule associated tumor suppressor 1
MUC1 mucin 1, cell surface associated
MYH10 myosin, heavy chain 10, non-muscle
NCOA2 nuclear receptor coactivator 2
NDNF neuron-derived neurotrophic factor
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPDC1 neural proliferation, differentiation and control, 1
OAZ3 ornithine decarboxylase antizyme 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCGF2 polycomb group ring finger 2
PEX1 peroxisomal biogenesis factor 1
PFKM phosphofructokinase, muscle
PHTF2 putative homeodomain transcription factor 2
PLAC1 placenta-specific 1
PLCG1 phospholipase C, gamma 1
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PRF1 perforin 1 (pore forming protein)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PROCR protein C receptor, endothelial
PTN pleiotrophin
PYGB phosphorylase, glycogen; brain
QPCT glutaminyl-peptide cyclotransferase
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGS10 regulator of G-protein signaling 10
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RUSC2 RUN and SH3 domain containing 2
SCAI suppressor of cancer cell invasion
SIRT5 sirtuin 5
SLC16A4 solute carrier family 16, member 4
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC39A9 solute carrier family 39, member 9
SLC44A1 solute carrier family 44 (choline transporter), member 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAP1 signal transducing adaptor family member 1
STK38L serine/threonine kinase 38 like
TAPT1 transmembrane anterior posterior transformation 1
TEX40 testis expressed 40
THOC5 THO complex 5
TMOD1 tropomodulin 1
TNNT1 troponin T type 1 (skeletal, slow)
TPD52L1 tumor protein D52-like 1
TPM1 tropomyosin 1 (alpha)
TPMT thiopurine S-methyltransferase
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TULP4 tubby like protein 4
UST uronyl-2-sulfotransferase
WLS wntless Wnt ligand secretion mediator
WNT16 wingless-type MMTV integration site family, member 16
ZC4H2 zinc finger, C4H2 domain containing
ZNF345 zinc finger protein 345

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABHD4 abhydrolase domain containing 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARHGAP12 Rho GTPase activating protein 12
ARMC6 armadillo repeat containing 6
AUH AU RNA binding protein/enoyl-CoA hydratase
BAHCC1 BAH domain and coiled-coil containing 1
BCL7B B-cell CLL/lymphoma 7B
C10ORF2 chromosome 10 open reading frame 2
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C1ORF35 chromosome 1 open reading frame 35
CARD9 caspase recruitment domain family, member 9
CCDC94 coiled-coil domain containing 94
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCNJ cyclin J
CD82 CD82 molecule
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHMP7 charged multivesicular body protein 7
CINP cyclin-dependent kinase 2 interacting protein
CPNE1 copine I
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTPS1 CTP synthase 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBF4B DBF4 zinc finger B
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ERO1L ERO1-like (S. cerevisiae)
FAM53B family with sequence similarity 53, member B
FGL2 fibrinogen-like 2
FOXN2 forkhead box N2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRAMD1B GRAM domain containing 1B
HIST1H2BI histone cluster 1, H2bi
HRAS Harvey rat sarcoma viral oncogene homolog
IFI35 interferon-induced protein 35
IFITM3 interferon induced transmembrane protein 3
IL4R interleukin 4 receptor
KAT2A K(lysine) acetyltransferase 2A
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LAX1 lymphocyte transmembrane adaptor 1
LSP1 lymphocyte-specific protein 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEB2 melanoma antigen family B2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK12 mitogen-activated protein kinase 12
MCRS1 microspherule protein 1
NHEJ1 nonhomologous end-joining factor 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PEX26 peroxisomal biogenesis factor 26
PISD phosphatidylserine decarboxylase
PNMA1 paraneoplastic Ma antigen 1
PNOC prepronociceptin
PPARG peroxisome proliferator-activated receptor gamma
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS13 regulator of G-protein signaling 13
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNH1 ribonuclease/angiogenin inhibitor 1
RPAP1 RNA polymerase II associated protein 1
SAMD9 sterile alpha motif domain containing 9
SETD6 SET domain containing 6
SIL1 SIL1 nucleotide exchange factor
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SREK1IP1 SREK1-interacting protein 1
STAG1 stromal antigen 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SURF2 surfeit 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM8A transmembrane protein 8A
TPK1 thiamin pyrophosphokinase 1
TRABD TraB domain containing
TSPYL2 TSPY-like 2
TTC4 tetratricopeptide repeat domain 4
TXLNG taxilin gamma
UBIAD1 UbiA prenyltransferase domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
VSIG4 V-set and immunoglobulin domain containing 4
WDR43 WD repeat domain 43
WDR5B WD repeat domain 5B
WNT10B wingless-type MMTV integration site family, member 10B
ZNF140 zinc finger protein 140
ZNF16 zinc finger protein 16
ZNF408 zinc finger protein 408
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675
ZNF787 zinc finger protein 787
ZSCAN5A zinc finger and SCAN domain containing 5A