valproic acid-1163 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the valproic acid-1163 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACOX3 acyl-CoA oxidase 3, pristanoyl
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMDHD2 amidohydrolase domain containing 2
APOLD1 apolipoprotein L domain containing 1
APP amyloid beta (A4) precursor protein
ARMC7 armadillo repeat containing 7
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BICD1 bicaudal D homolog 1 (Drosophila)
C4ORF29 chromosome 4 open reading frame 29
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCL20 chemokine (C-C motif) ligand 20
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD84 CD84 molecule
CDC14A cell division cycle 14A
CDC25C cell division cycle 25C
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLTA clathrin, light chain A
CPVL carboxypeptidase, vitellogenic-like
CRYL1 crystallin, lambda 1
CTBP1 C-terminal binding protein 1
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAL4 dynein, axonemal, light chain 4
DOCK5 dedicator of cytokinesis 5
DRG2 developmentally regulated GTP binding protein 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EIF1 eukaryotic translation initiation factor 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EVA1B eva-1 homolog B (C. elegans)
EZR ezrin
F11R F11 receptor
F5 coagulation factor V (proaccelerin, labile factor)
FAM163A family with sequence similarity 163, member A
FAM63A family with sequence similarity 63, member A
FLT4 fms-related tyrosine kinase 4
FNTB farnesyltransferase, CAAX box, beta
GCFC2 GC-rich sequence DNA-binding factor 2
GLIPR1 GLI pathogenesis-related 1
GM2A GM2 ganglioside activator
IGL immunoglobulin lambda locus
INCENP inner centromere protein antigens 135/155kDa
ITSN1 intersectin 1 (SH3 domain protein)
KDM4C lysine (K)-specific demethylase 4C
KDM8 lysine (K)-specific demethylase 8
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRT24 keratin 24, type I
MAGOH2P mago-nashi homolog 2, pseudogene
MAP4 microtubule-associated protein 4
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARK4 MAP/microtubule affinity-regulating kinase 4
MLH3 mutL homolog 3
N4BP1 NEDD4 binding protein 1
NCS1 neuronal calcium sensor 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT2 N-myristoyltransferase 2
NPM3 nucleophosmin/nucleoplasmin 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PALLD palladin, cytoskeletal associated protein
PAOX polyamine oxidase (exo-N4-amino)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCGF2 polycomb group ring finger 2
PGAP1 post-GPI attachment to proteins 1
PHF20L1 PHD finger protein 20-like 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
POU3F2 POU class 3 homeobox 2
PPP5C protein phosphatase 5, catalytic subunit
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRB protein tyrosine phosphatase, receptor type, B
PWAR5 Prader Willi/Angelman region RNA 5
PYGB phosphorylase, glycogen; brain
RABEPK Rab9 effector protein with kelch motifs
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCAI suppressor of cancer cell invasion
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC38A7 solute carrier family 38, member 7
SMAD5 SMAD family member 5
SOX12 SRY (sex determining region Y)-box 12
SUSD4 sushi domain containing 4
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TRAF1 TNF receptor-associated factor 1
TRIM3 tripartite motif containing 3
TSPAN2 tetraspanin 2
TSPAN32 tetraspanin 32
TTC38 tetratricopeptide repeat domain 38
TUBG2 tubulin, gamma 2
UNC119 unc-119 homolog (C. elegans)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ANAPC2 anaphase promoting complex subunit 2
APOBR apolipoprotein B receptor
BBC3 BCL2 binding component 3
BCL7B B-cell CLL/lymphoma 7B
C16ORF59 chromosome 16 open reading frame 59
C19ORF40 chromosome 19 open reading frame 40
C1QTNF3 C1q and tumor necrosis factor related protein 3
CEP97 centrosomal protein 97kDa
CHMP1A charged multivesicular body protein 1A
CLEC4E C-type lectin domain family 4, member E
CLSTN1 calsyntenin 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOLK dolichol kinase
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM50B family with sequence similarity 50, member B
FAM53B family with sequence similarity 53, member B
FES FES proto-oncogene, tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
FMNL1 formin-like 1
FOSL1 FOS-like antigen 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
HDAC5 histone deacetylase 5
IFI6 interferon, alpha-inducible protein 6
IFT81 intraflagellar transport 81
IL4R interleukin 4 receptor
INPPL1 inositol polyphosphate phosphatase-like 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JUNB jun B proto-oncogene
KCNK5 potassium channel, two pore domain subfamily K, member 5
KLF2 Kruppel-like factor 2
KLHL21 kelch-like family member 21
LAX1 lymphocyte transmembrane adaptor 1
LRRC37A3 leucine rich repeat containing 37, member A3
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK3 mitogen-activated protein kinase 3
MAST3 microtubule associated serine/threonine kinase 3
MUM1 melanoma associated antigen (mutated) 1
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NT5E 5'-nucleotidase, ecto (CD73)
NT5M 5',3'-nucleotidase, mitochondrial
OCEL1 occludin/ELL domain containing 1
OSTM1 osteopetrosis associated transmembrane protein 1
PDGFD platelet derived growth factor D
PIAS3 protein inhibitor of activated STAT, 3
PLA2G12A phospholipase A2, group XIIA
PLTP phospholipid transfer protein
PNOC prepronociceptin
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
POR P450 (cytochrome) oxidoreductase
PROSER1 proline and serine rich 1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RBL1 retinoblastoma-like 1
RHOBTB1 Rho-related BTB domain containing 1
RNF2 ring finger protein 2
RPA4 replication protein A4, 30kDa
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SEC31B SEC31 homolog B (S. cerevisiae)
SERINC5 serine incorporator 5
SERTAD3 SERTA domain containing 3
SETD6 SET domain containing 6
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX16 sorting nexin 16
SPATA7 spermatogenesis associated 7
SPATS2 spermatogenesis associated, serine-rich 2
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SSFA2 sperm specific antigen 2
STBD1 starch binding domain 1
STEAP3 STEAP family member 3, metalloreductase
STIM1 stromal interaction molecule 1
TBX19 T-box 19
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TOR4A torsin family 4, member A
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ULK1 unc-51 like autophagy activating kinase 1
UPP1 uridine phosphorylase 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VANGL1 VANGL planar cell polarity protein 1
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
WT1-AS WT1 antisense RNA
WWC3 WWC family member 3
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF10 zinc finger protein 10
ZNF212 zinc finger protein 212
ZNF282 zinc finger protein 282
ZNF536 zinc finger protein 536
ZNF551 zinc finger protein 551
ZNF747 zinc finger protein 747