Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the valproic acid-1181 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD6 | abhydrolase domain containing 6 |
ABI2 | abl-interactor 2 |
ADGRL3 | adhesion G protein-coupled receptor L3 |
ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
ANKRD6 | ankyrin repeat domain 6 |
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
AREG | amphiregulin |
ATG3 | autophagy related 3 |
ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
BMP2K | BMP2 inducible kinase |
CALD1 | caldesmon 1 |
CD59 | CD59 molecule, complement regulatory protein |
CDON | cell adhesion associated, oncogene regulated |
CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
CSHL1 | chorionic somatomammotropin hormone-like 1 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DOCK4 | dedicator of cytokinesis 4 |
DUSP4 | dual specificity phosphatase 4 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
DZIP3 | DAZ interacting zinc finger protein 3 |
FAM155A | family with sequence similarity 155, member A |
FAM63A | family with sequence similarity 63, member A |
FAS | Fas cell surface death receptor |
FBXL18 | F-box and leucine-rich repeat protein 18 |
FGF9 | fibroblast growth factor 9 |
FGL2 | fibrinogen-like 2 |
FHL1 | four and a half LIM domains 1 |
FNBP1L | formin binding protein 1-like |
FSTL3 | follistatin-like 3 (secreted glycoprotein) |
GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
GBP1 | guanylate binding protein 1, interferon-inducible |
GPM6B | glycoprotein M6B |
HEMK1 | HemK methyltransferase family member 1 |
HIST1H2AI | histone cluster 1, H2ai |
HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 |
IDS | iduronate 2-sulfatase |
IGFBP5 | insulin-like growth factor binding protein 5 |
IGKV3-20 | immunoglobulin kappa variable 3-20 |
IL12RB2 | interleukin 12 receptor, beta 2 |
ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
KIAA0485 | uncharacterized LOC57235 |
L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
LIMD1 | LIM domains containing 1 |
LINC00597 | long intergenic non-protein coding RNA 597 |
LMAN1 | lectin, mannose-binding, 1 |
LRP6 | low density lipoprotein receptor-related protein 6 |
MAGEF1 | melanoma antigen family F1 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MAP2K6 | mitogen-activated protein kinase kinase 6 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MPPE1 | metallophosphoesterase 1 |
MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
NLK | nemo-like kinase |
NOX1 | NADPH oxidase 1 |
PCCA | propionyl CoA carboxylase, alpha polypeptide |
PCDH12 | protocadherin 12 |
PCDHB17P | protocadherin beta 17 pseudogene |
PDGFRL | platelet-derived growth factor receptor-like |
PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PLS1 | plastin 1 |
POU4F1 | POU class 4 homeobox 1 |
PRB1 | proline-rich protein BstNI subfamily 1 |
PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
PTPRS | protein tyrosine phosphatase, receptor type, S |
QPCT | glutaminyl-peptide cyclotransferase |
RAB40B | RAB40B, member RAS oncogene family |
REEP1 | receptor accessory protein 1 |
RFPL1 | ret finger protein-like 1 |
RGS12 | regulator of G-protein signaling 12 |
RHOBTB3 | Rho-related BTB domain containing 3 |
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
SH3D21 | SH3 domain containing 21 |
SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
SLC22A17 | solute carrier family 22, member 17 |
SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
STAP2 | signal transducing adaptor family member 2 |
STEAP3 | STEAP family member 3, metalloreductase |
STRN3 | striatin, calmodulin binding protein 3 |
TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
THOC5 | THO complex 5 |
TNS2 | tensin 2 |
TPD52 | tumor protein D52 |
TPD52L1 | tumor protein D52-like 1 |
TRAF1 | TNF receptor-associated factor 1 |
TSPAN13 | tetraspanin 13 |
TUBB2A | tubulin, beta 2A class IIa |
UROD | uroporphyrinogen decarboxylase |
WLS | wntless Wnt ligand secretion mediator |
ZNF277 | zinc finger protein 277 |
ZNF345 | zinc finger protein 345 |
ZNF862 | zinc finger protein 862 |
Symbol | Name |
---|---|
ACPP | acid phosphatase, prostate |
ACY1 | aminoacylase 1 |
AFG3L2 | AFG3-like AAA ATPase 2 |
ANKRD11 | ankyrin repeat domain 11 |
ANKRD55 | ankyrin repeat domain 55 |
ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
ASCC2 | activating signal cointegrator 1 complex subunit 2 |
BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
BATF | basic leucine zipper transcription factor, ATF-like |
BOLA1 | bolA family member 1 |
C11ORF21 | chromosome 11 open reading frame 21 |
C19ORF24 | chromosome 19 open reading frame 24 |
C2CD2 | C2 calcium-dependent domain containing 2 |
CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
CASC3 | cancer susceptibility candidate 3 |
CD38 | CD38 molecule |
CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
CHMP7 | charged multivesicular body protein 7 |
CISH | cytokine inducible SH2-containing protein |
CLSPN | claspin |
CLTCL1 | clathrin, heavy chain-like 1 |
CLUH | clustered mitochondria (cluA/CLU1) homolog |
CRTAP | cartilage associated protein |
CSF1R | colony stimulating factor 1 receptor |
DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
DOLK | dolichol kinase |
EXD2 | exonuclease 3'-5' domain containing 2 |
FADS2 | fatty acid desaturase 2 |
FAM188A | family with sequence similarity 188, member A |
FES | FES proto-oncogene, tyrosine kinase |
FGR | FGR proto-oncogene, Src family tyrosine kinase |
FXN | frataxin |
GMPPA | GDP-mannose pyrophosphorylase A |
GPATCH3 | G patch domain containing 3 |
GRAMD1B | GRAM domain containing 1B |
GRWD1 | glutamate-rich WD repeat containing 1 |
GYPC | glycophorin C (Gerbich blood group) |
IL17RA | interleukin 17 receptor A |
IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
INPPL1 | inositol polyphosphate phosphatase-like 1 |
KIAA0894 | KIAA0894 protein |
LGALS9 | lectin, galactoside-binding, soluble, 9 |
LUC7L | LUC7-like (S. cerevisiae) |
MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
MAP7D1 | MAP7 domain containing 1 |
MBTD1 | mbt domain containing 1 |
MED15 | mediator complex subunit 15 |
MEPCE | methylphosphate capping enzyme |
METTL8 | methyltransferase like 8 |
MON1B | MON1 secretory trafficking family member B |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MTG1 | mitochondrial ribosome-associated GTPase 1 |
MYLIP | myosin regulatory light chain interacting protein |
NCF1C | neutrophil cytosolic factor 1C pseudogene |
NHEJ1 | nonhomologous end-joining factor 1 |
NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
NOTCH1 | notch 1 |
NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
PEX26 | peroxisomal biogenesis factor 26 |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 |
PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
PRKCZ | protein kinase C, zeta |
PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
PUS1 | pseudouridylate synthase 1 |
QTRT1 | queuine tRNA-ribosyltransferase 1 |
RAD54L | RAD54-like (S. cerevisiae) |
RETN | resistin |
RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
RGS13 | regulator of G-protein signaling 13 |
RGS19 | regulator of G-protein signaling 19 |
SARS2 | seryl-tRNA synthetase 2, mitochondrial |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
SH2D3C | SH2 domain containing 3C |
SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
SNIP1 | Smad nuclear interacting protein 1 |
SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
TERT | telomerase reverse transcriptase |
TEX2 | testis expressed 2 |
TMED1 | transmembrane emp24 protein transport domain containing 1 |
TMEM164 | transmembrane protein 164 |
TNIP1 | TNFAIP3 interacting protein 1 |
TTC4 | tetratricopeptide repeat domain 4 |
USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
VAV1 | vav 1 guanine nucleotide exchange factor |
VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 |
VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
WT1-AS | WT1 antisense RNA |
XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
ZNF212 | zinc finger protein 212 |
ZNF721 | zinc finger protein 721 |
ZNF787 | zinc finger protein 787 |