valproic acid-1181 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the valproic acid-1181 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ABI2 abl-interactor 2
ADGRL3 adhesion G protein-coupled receptor L3
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD6 ankyrin repeat domain 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AREG amphiregulin
ATG3 autophagy related 3
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP2K BMP2 inducible kinase
CALD1 caldesmon 1
CD59 CD59 molecule, complement regulatory protein
CDON cell adhesion associated, oncogene regulated
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CSHL1 chorionic somatomammotropin hormone-like 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DOCK4 dedicator of cytokinesis 4
DUSP4 dual specificity phosphatase 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DZIP3 DAZ interacting zinc finger protein 3
FAM155A family with sequence similarity 155, member A
FAM63A family with sequence similarity 63, member A
FAS Fas cell surface death receptor
FBXL18 F-box and leucine-rich repeat protein 18
FGF9 fibroblast growth factor 9
FGL2 fibrinogen-like 2
FHL1 four and a half LIM domains 1
FNBP1L formin binding protein 1-like
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GBP1 guanylate binding protein 1, interferon-inducible
GPM6B glycoprotein M6B
HEMK1 HemK methyltransferase family member 1
HIST1H2AI histone cluster 1, H2ai
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
IDS iduronate 2-sulfatase
IGFBP5 insulin-like growth factor binding protein 5
IGKV3-20 immunoglobulin kappa variable 3-20
IL12RB2 interleukin 12 receptor, beta 2
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KIAA0485 uncharacterized LOC57235
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIMD1 LIM domains containing 1
LINC00597 long intergenic non-protein coding RNA 597
LMAN1 lectin, mannose-binding, 1
LRP6 low density lipoprotein receptor-related protein 6
MAGEF1 melanoma antigen family F1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP2K6 mitogen-activated protein kinase kinase 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MPPE1 metallophosphoesterase 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NLK nemo-like kinase
NOX1 NADPH oxidase 1
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDH12 protocadherin 12
PCDHB17P protocadherin beta 17 pseudogene
PDGFRL platelet-derived growth factor receptor-like
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PRB1 proline-rich protein BstNI subfamily 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTPRS protein tyrosine phosphatase, receptor type, S
QPCT glutaminyl-peptide cyclotransferase
RAB40B RAB40B, member RAS oncogene family
REEP1 receptor accessory protein 1
RFPL1 ret finger protein-like 1
RGS12 regulator of G-protein signaling 12
RHOBTB3 Rho-related BTB domain containing 3
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCGB2A2 secretoglobin, family 2A, member 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SH3D21 SH3 domain containing 21
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC22A17 solute carrier family 22, member 17
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STAP2 signal transducing adaptor family member 2
STEAP3 STEAP family member 3, metalloreductase
STRN3 striatin, calmodulin binding protein 3
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
THOC5 THO complex 5
TNS2 tensin 2
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
TRAF1 TNF receptor-associated factor 1
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
UROD uroporphyrinogen decarboxylase
WLS wntless Wnt ligand secretion mediator
ZNF277 zinc finger protein 277
ZNF345 zinc finger protein 345
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ACY1 aminoacylase 1
AFG3L2 AFG3-like AAA ATPase 2
ANKRD11 ankyrin repeat domain 11
ANKRD55 ankyrin repeat domain 55
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASCC2 activating signal cointegrator 1 complex subunit 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BATF basic leucine zipper transcription factor, ATF-like
BOLA1 bolA family member 1
C11ORF21 chromosome 11 open reading frame 21
C19ORF24 chromosome 19 open reading frame 24
C2CD2 C2 calcium-dependent domain containing 2
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CASC3 cancer susceptibility candidate 3
CD38 CD38 molecule
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHMP7 charged multivesicular body protein 7
CISH cytokine inducible SH2-containing protein
CLSPN claspin
CLTCL1 clathrin, heavy chain-like 1
CLUH clustered mitochondria (cluA/CLU1) homolog
CRTAP cartilage associated protein
CSF1R colony stimulating factor 1 receptor
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOLK dolichol kinase
EXD2 exonuclease 3'-5' domain containing 2
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FES FES proto-oncogene, tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
FXN frataxin
GMPPA GDP-mannose pyrophosphorylase A
GPATCH3 G patch domain containing 3
GRAMD1B GRAM domain containing 1B
GRWD1 glutamate-rich WD repeat containing 1
GYPC glycophorin C (Gerbich blood group)
IL17RA interleukin 17 receptor A
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPPL1 inositol polyphosphate phosphatase-like 1
KIAA0894 KIAA0894 protein
LGALS9 lectin, galactoside-binding, soluble, 9
LUC7L LUC7-like (S. cerevisiae)
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP7D1 MAP7 domain containing 1
MBTD1 mbt domain containing 1
MED15 mediator complex subunit 15
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MON1B MON1 secretory trafficking family member B
MPDU1 mannose-P-dolichol utilization defect 1
MTG1 mitochondrial ribosome-associated GTPase 1
MYLIP myosin regulatory light chain interacting protein
NCF1C neutrophil cytosolic factor 1C pseudogene
NHEJ1 nonhomologous end-joining factor 1
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOTCH1 notch 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRKCZ protein kinase C, zeta
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PUS1 pseudouridylate synthase 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAD54L RAD54-like (S. cerevisiae)
RETN resistin
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RGS13 regulator of G-protein signaling 13
RGS19 regulator of G-protein signaling 19
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SH2D3C SH2 domain containing 3C
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNIP1 Smad nuclear interacting protein 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TERT telomerase reverse transcriptase
TEX2 testis expressed 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM164 transmembrane protein 164
TNIP1 TNFAIP3 interacting protein 1
TTC4 tetratricopeptide repeat domain 4
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAV1 vav 1 guanine nucleotide exchange factor
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WT1-AS WT1 antisense RNA
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF212 zinc finger protein 212
ZNF721 zinc finger protein 721
ZNF787 zinc finger protein 787