valproic acid-1209 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the valproic acid-1209 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABHD2 abhydrolase domain containing 2
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP13 A kinase (PRKA) anchor protein 13
AKAP5 A kinase (PRKA) anchor protein 5
BAMBI BMP and activin membrane-bound inhibitor
BATF3 basic leucine zipper transcription factor, ATF-like 3
BTBD7 BTB (POZ) domain containing 7
C1ORF159 chromosome 1 open reading frame 159
C2CD2L C2CD2-like
CA5B carbonic anhydrase VB, mitochondrial
CALD1 caldesmon 1
CCDC186 coiled-coil domain containing 186
CDC42 cell division cycle 42
CDYL chromodomain protein, Y-like
CHN2 chimerin 2
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DTX4 deltex 4, E3 ubiquitin ligase
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
EMP1 epithelial membrane protein 1
FAM69A family with sequence similarity 69, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHOD1 formin homology 2 domain containing 1
FMO5 flavin containing monooxygenase 5
FOXN3 forkhead box N3
FYN FYN proto-oncogene, Src family tyrosine kinase
GPR4 G protein-coupled receptor 4
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1FX H1 histone family, member X
HHIPL2 HHIP-like 2
IFT27 intraflagellar transport 27
INO80B INO80 complex subunit B
ISL1 ISL LIM homeobox 1
ITSN1 intersectin 1 (SH3 domain protein)
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA0485 uncharacterized LOC57235
KIAA0895 KIAA0895
KRIT1 KRIT1, ankyrin repeat containing
LPPR4 lipid phosphate phosphatase-related protein type 4
LUM lumican
LY6G6C lymphocyte antigen 6 complex, locus G6C
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTSS1 metastasis suppressor 1
MVK mevalonate kinase
NCAPH2 non-SMC condensin II complex, subunit H2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PCDH7 protocadherin 7
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHF1 PHD finger protein 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP1R7 protein phosphatase 1, regulatory subunit 7
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTAFR platelet-activating factor receptor
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB28 RAB28, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGS10 regulator of G-protein signaling 10
RGS4 regulator of G-protein signaling 4
S1PR1 sphingosine-1-phosphate receptor 1
SATB1 SATB homeobox 1
SDC2 syndecan 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMG5 SMG5 nonsense mediated mRNA decay factor
SMG6 SMG6 nonsense mediated mRNA decay factor
SORBS2 sorbin and SH3 domain containing 2
SOSTDC1 sclerostin domain containing 1
SPATA2L spermatogenesis associated 2-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STX5 syntaxin 5
SYT1 synaptotagmin I
TESK1 testis-specific kinase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGFBR3 transforming growth factor, beta receptor III
TLE2 transducin-like enhancer of split 2
TNIK TRAF2 and NCK interacting kinase
TRADD TNFRSF1A-associated via death domain
TRIM2 tripartite motif containing 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBXN1 UBX domain protein 1
UGT8 UDP glycosyltransferase 8
USB1 U6 snRNA biogenesis 1
VGLL3 vestigial-like family member 3
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
AATK apoptosis-associated tyrosine kinase
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AEN apoptosis enhancing nuclease
ANAPC2 anaphase promoting complex subunit 2
ANXA2P3 annexin A2 pseudogene 3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARL14 ADP-ribosylation factor-like 14
ARMC6 armadillo repeat containing 6
ATF1 activating transcription factor 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCKDK branched chain ketoacid dehydrogenase kinase
C19ORF40 chromosome 19 open reading frame 40
C2CD5 C2 calcium-dependent domain containing 5
C9ORF114 chromosome 9 open reading frame 114
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBR4 carbonyl reductase 4
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK3 cyclin-dependent kinase 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP7 charged multivesicular body protein 7
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CTSD cathepsin D
DET1 de-etiolated homolog 1 (Arabidopsis)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DOLPP1 dolichyldiphosphatase 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM50B family with sequence similarity 50, member B
FANCF Fanconi anemia, complementation group F
FBXO2 F-box protein 2
FBXO46 F-box protein 46
FGF1 fibroblast growth factor 1 (acidic)
FNTB farnesyltransferase, CAAX box, beta
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIRIP3 HIRA interacting protein 3
ICE2 interactor of little elongation complex ELL subunit 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
LMBR1L limb development membrane protein 1-like
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD3 LY6/PLAUR domain containing 3
MANEA mannosidase, endo-alpha
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MFSD10 major facilitator superfamily domain containing 10
MKS1 Meckel syndrome, type 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NHEJ1 nonhomologous end-joining factor 1
NLRX1 NLR family member X1
NUBP1 nucleotide binding protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
POLM polymerase (DNA directed), mu
PPAN peter pan homolog (Drosophila)
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PROSER1 proline and serine rich 1
PRR15L proline rich 15-like
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS16 protease, serine, 16 (thymus)
PTK6 protein tyrosine kinase 6
RABGGTA Rab geranylgeranyltransferase, alpha subunit
SCAMP4 secretory carrier membrane protein 4
SETD1B SET domain containing 1B
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SREBF1 sterol regulatory element binding transcription factor 1
STAG1 stromal antigen 1
THAP1 THAP domain containing, apoptosis associated protein 1
THAP7 THAP domain containing 7
THBS3 thrombospondin 3
TMBIM1 transmembrane BAX inhibitor motif containing 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSSC4 tumor suppressing subtransferable candidate 4
UBXN8 UBX domain protein 8
USP21 ubiquitin specific peptidase 21
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB3 zinc finger and BTB domain containing 3
ZNF16 zinc finger protein 16
ZNF33B zinc finger protein 33B
ZNF552 zinc finger protein 552
ZZZ3 zinc finger, ZZ-type containing 3