valproic acid-1214 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the valproic acid-1214 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APC adenomatous polyposis coli
ATP11A ATPase, class VI, type 11A
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BICC1 BicC family RNA binding protein 1
C9ORF156 chromosome 9 open reading frame 156
CA12 carbonic anhydrase XII
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH7 cadherin 7, type 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP250 centrosomal protein 250kDa
CHN2 chimerin 2
CNOT8 CCR4-NOT transcription complex, subunit 8
CTSZ cathepsin Z
CXCR4 chemokine (C-X-C motif) receptor 4
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DNAAF1 dynein, axonemal, assembly factor 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EGR2 early growth response 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM174B family with sequence similarity 174, member B
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GSK3A glycogen synthase kinase 3 alpha
HEG1 heart development protein with EGF-like domains 1
HIC2 hypermethylated in cancer 2
HLA-DMA major histocompatibility complex, class II, DM alpha
HRH1 histamine receptor H1
ICA1 islet cell autoantigen 1, 69kDa
IGFBP5 insulin-like growth factor binding protein 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IRGQ immunity-related GTPase family, Q
KIAA0754 KIAA0754
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMA4 laminin, alpha 4
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP1 low density lipoprotein receptor-related protein 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1A microtubule-associated protein 1A
MERTK MER proto-oncogene, tyrosine kinase
METTL7A methyltransferase like 7A
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NPR3 natriuretic peptide receptor 3
NXPH4 neurexophilin 4
PAIP2B poly(A) binding protein interacting protein 2B
PBX1 pre-B-cell leukemia homeobox 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE10A phosphodiesterase 10A
PDGFB platelet-derived growth factor beta polypeptide
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLSCR4 phospholipid scramblase 4
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRB protein tyrosine phosphatase, receptor type, B
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGS14 regulator of G-protein signaling 14
RPP25 ribonuclease P/MRP 25kDa subunit
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERHL2 serine hydrolase-like 2
SFTPC surfactant protein C
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOSTDC1 sclerostin domain containing 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAT4 signal transducer and activator of transcription 4
STK4 serine/threonine kinase 4
STON1 stonin 1
STX16 syntaxin 16
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYT11 synaptotagmin XI
SYT17 synaptotagmin XVII
TBC1D22A TBC1 domain family, member 22A
TBC1D30 TBC1 domain family, member 30
TBXA2R thromboxane A2 receptor
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMF1 TATA element modulatory factor 1
TRABD TraB domain containing
TRAF2 TNF receptor-associated factor 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUSC2 tumor suppressor candidate 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
UEVLD UEV and lactate/malate dehyrogenase domains
UGT8 UDP glycosyltransferase 8
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
AGMAT agmatine ureohydrolase (agmatinase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANXA2P3 annexin A2 pseudogene 3
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARMC6 armadillo repeat containing 6
BMP2 bone morphogenetic protein 2
BTC betacellulin
C10ORF2 chromosome 10 open reading frame 2
CARD8 caspase recruitment domain family, member 8
CENPQ centromere protein Q
CLCN5 chloride channel, voltage-sensitive 5
CNPY3 canopy FGF signaling regulator 3
CNTNAP3B contactin associated protein-like 3B
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSF cathepsin F
CXORF56 chromosome X open reading frame 56
DEPTOR DEP domain containing MTOR-interacting protein
DSPP dentin sialophosphoprotein
ELP6 elongator acetyltransferase complex subunit 6
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EVPL envoplakin
FGD1 FYVE, RhoGEF and PH domain containing 1
FSD1 fibronectin type III and SPRY domain containing 1
GALT galactose-1-phosphate uridylyltransferase
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GMEB1 glucocorticoid modulatory element binding protein 1
HINFP histone H4 transcription factor
HIRIP3 HIRA interacting protein 3
HIST1H2AI histone cluster 1, H2ai
HOXA2 homeobox A2
HPS6 Hermansky-Pudlak syndrome 6
INCENP inner centromere protein antigens 135/155kDa
IREB2 iron-responsive element binding protein 2
KPTN kaptin (actin binding protein)
LOC100127972 uncharacterized LOC100127972
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAGEF1 melanoma antigen family F1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MILR1 mast cell immunoglobulin-like receptor 1
MMP9 matrix metallopeptidase 9
MOCS3 molybdenum cofactor synthesis 3
MTERF4 mitochondrial transcription termination factor 4
MTG1 mitochondrial ribosome-associated GTPase 1
MUM1 melanoma associated antigen (mutated) 1
NDP Norrie disease (pseudoglioma)
NR1H2 nuclear receptor subfamily 1, group H, member 2
NT5DC3 5'-nucleotidase domain containing 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLH polymerase (DNA directed), eta
POMT2 protein-O-mannosyltransferase 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTDSS2 phosphatidylserine synthase 2
PTGFR prostaglandin F receptor (FP)
RARS arginyl-tRNA synthetase
RNF122 ring finger protein 122
RPS17P5 ribosomal protein S17 pseudogene 5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCAF8 SR-related CTD-associated factor 8
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNPH syntaphilin
SP140L SP140 nuclear body protein-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAGLN transgelin
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM254 transmembrane protein 254
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNRC6B trinucleotide repeat containing 6B
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM58 tripartite motif containing 58
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBXN8 UBX domain protein 8
USP6NL USP6 N-terminal like
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WASF1 WAS protein family, member 1
XAB2 XPA binding protein 2
YEATS4 YEATS domain containing 4
ZNF205 zinc finger protein 205
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF552 zinc finger protein 552
ZNF696 zinc finger protein 696
ZNF787 zinc finger protein 787