valproic acid-1240 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the valproic acid-1240 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
AKAP5 A kinase (PRKA) anchor protein 5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APC adenomatous polyposis coli
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARTN artemin
ASIC1 acid sensing (proton gated) ion channel 1
ATAD5 ATPase family, AAA domain containing 5
BATF3 basic leucine zipper transcription factor, ATF-like 3
C7ORF43 chromosome 7 open reading frame 43
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH7 cadherin 7, type 2
CHMP6 charged multivesicular body protein 6
CHN2 chimerin 2
CHRM3 cholinergic receptor, muscarinic 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CUL2 cullin 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
ELOVL6 ELOVL fatty acid elongase 6
ESRRG estrogen-related receptor gamma
FAM174B family with sequence similarity 174, member B
FAM69A family with sequence similarity 69, member A
FAS Fas cell surface death receptor
FPGS folylpolyglutamate synthase
FYN FYN proto-oncogene, Src family tyrosine kinase
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRIP2 glutamate receptor interacting protein 2
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HOXC5 homeobox C5
ITGA7 integrin, alpha 7
ITSN1 intersectin 1 (SH3 domain protein)
KLHL36 kelch-like family member 36
KRIT1 KRIT1, ankyrin repeat containing
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAT2 linker for activation of T cells family, member 2
LPPR4 lipid phosphate phosphatase-related protein type 4
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LTBP4 latent transforming growth factor beta binding protein 4
LYZ lysozyme
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MERTK MER proto-oncogene, tyrosine kinase
N4BP2L1 NEDD4 binding protein 2-like 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PCM1 pericentriolar material 1
PDGFB platelet-derived growth factor beta polypeptide
PHF20L1 PHD finger protein 20-like 1
PHTF2 putative homeodomain transcription factor 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLG polymerase (DNA directed), gamma
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGES prostaglandin E synthase
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGAP1L RAB GTPase activating protein 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS14 regulator of G-protein signaling 14
RGS4 regulator of G-protein signaling 4
RPP25 ribonuclease P/MRP 25kDa subunit
RPS3A ribosomal protein S3A
RTEL1 regulator of telomere elongation helicase 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLITRK5 SLIT and NTRK-like family, member 5
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNX13 sorting nexin 13
SOSTDC1 sclerostin domain containing 1
SRPK2 SRSF protein kinase 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STS steroid sulfatase (microsomal), isozyme S
SYT1 synaptotagmin I
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D17 TBC1 domain family, member 17
TCF4 transcription factor 4
TCP11L1 t-complex 11, testis-specific-like 1
TFCP2L1 transcription factor CP2-like 1
TLR2 toll-like receptor 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM25 tripartite motif containing 25
UNC93B1 unc-93 homolog B1 (C. elegans)
USB1 U6 snRNA biogenesis 1
VGLL3 vestigial-like family member 3
ZNF467 zinc finger protein 467
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCAR3 breast cancer anti-estrogen resistance 3
BFAR bifunctional apoptosis regulator
BMP2 bone morphogenetic protein 2
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C1ORF105 chromosome 1 open reading frame 105
C8ORF44 chromosome 8 open reading frame 44
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCDC106 coiled-coil domain containing 106
CCL20 chemokine (C-C motif) ligand 20
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCF1 cardiotrophin-like cytokine factor 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CTSO cathepsin O
CUEDC1 CUE domain containing 1
DCLRE1A DNA cross-link repair 1A
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEAF1 DEAF1 transcription factor
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DTX2 deltex 2, E3 ubiquitin ligase
EDN1 endothelin 1
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
ESM1 endothelial cell-specific molecule 1
FAM120C family with sequence similarity 120C
FGF1 fibroblast growth factor 1 (acidic)
GBX2 gastrulation brain homeobox 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPATCH1 G patch domain containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HINFP histone H4 transcription factor
HIST1H2AE histone cluster 1, H2ae
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC4 homeobox C4
HSF2BP heat shock transcription factor 2 binding protein
IRF1 interferon regulatory factor 1
KIAA1462 KIAA1462
KIRREL kin of IRRE like (Drosophila)
KRT33A keratin 33A, type I
KRT8P12 keratin 8 pseudogene 12
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MATN3 matrilin 3
MMP9 matrix metallopeptidase 9
MUM1 melanoma associated antigen (mutated) 1
MYH9 myosin, heavy chain 9, non-muscle
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
ORAI3 ORAI calcium release-activated calcium modulator 3
OVGP1 oviductal glycoprotein 1, 120kDa
PARP3 poly (ADP-ribose) polymerase family, member 3
PC pyruvate carboxylase
PHC1 polyhomeotic homolog 1 (Drosophila)
PISD phosphatidylserine decarboxylase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLM polymerase (DNA directed), mu
PRR4 proline rich 4 (lacrimal)
PTK6 protein tyrosine kinase 6
RASA2 RAS p21 protein activator 2
RBM14 RNA binding motif protein 14
RBM38 RNA binding motif protein 38
RECQL4 RecQ protein-like 4
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A3 S100 calcium binding protein A3
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDAD1 SDA1 domain containing 1
SDC3 syndecan 3
SENP7 SUMO1/sentrin specific peptidase 7
SLC44A4 solute carrier family 44, member 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TGFB3 transforming growth factor, beta 3
TPCN1 two pore segment channel 1
UBXN8 UBX domain protein 8
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB44 zinc finger and BTB domain containing 44
ZBTB48 zinc finger and BTB domain containing 48
ZNF280D zinc finger protein 280D
ZNF767P zinc finger family member 767, pseudogene
ZNF804A zinc finger protein 804A