valproic acid-1639 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the valproic acid-1639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
AHR aryl hydrocarbon receptor
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARTN artemin
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L1 BCL2-like 1
CARF calcium responsive transcription factor
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC28B coiled-coil domain containing 28B
CCHCR1 coiled-coil alpha-helical rod protein 1
COL7A1 collagen, type VII, alpha 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DFNB31 deafness, autosomal recessive 31
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDRF1 erythroid differentiation regulatory factor 1
EHBP1L1 EH domain binding protein 1-like 1
EPOR erythropoietin receptor
FAM134B family with sequence similarity 134, member B
FAM46C family with sequence similarity 46, member C
FGF18 fibroblast growth factor 18
FH fumarate hydratase
FILIP1L filamin A interacting protein 1-like
FSCN1 fascin actin-bundling protein 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FYN FYN proto-oncogene, Src family tyrosine kinase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRSF1 G-rich RNA sequence binding factor 1
GYG2 glycogenin 2
HBEGF heparin-binding EGF-like growth factor
HIP1 huntingtin interacting protein 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KDM6A lysine (K)-specific demethylase 6A
KDM7A lysine (K)-specific demethylase 7A
KIAA0895 KIAA0895
KREMEN2 kringle containing transmembrane protein 2
LAMB1 laminin, beta 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
LTBP1 latent transforming growth factor beta binding protein 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MFAP2 microfibrillar-associated protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTSS1 metastasis suppressor 1
NDRG3 NDRG family member 3
NKX3-1 NK3 homeobox 1
NOX1 NADPH oxidase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OGFR opioid growth factor receptor
ORAI2 ORAI calcium release-activated calcium modulator 2
PCM1 pericentriolar material 1
PDGFB platelet-derived growth factor beta polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPK1 3-phosphoinositide dependent protein kinase 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PLAUR plasminogen activator, urokinase receptor
PLK3 polo-like kinase 3
POLL polymerase (DNA directed), lambda
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRPH peripherin
PTCH1 patched 1
PTRF polymerase I and transcript release factor
RAB11B RAB11B, member RAS oncogene family
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB14 RAB14, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBM12 RNA binding motif protein 12
RCAN1 regulator of calcineurin 1
REEP1 receptor accessory protein 1
RNF39 ring finger protein 39
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SMIM8 small integral membrane protein 8
SPDEF SAM pointed domain containing ETS transcription factor
STYK1 serine/threonine/tyrosine kinase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMSB15A thymosin beta 15a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TREX1 three prime repair exonuclease 1
TRIM25 tripartite motif containing 25
TSNAXIP1 translin-associated factor X interacting protein 1
TUBGCP3 tubulin, gamma complex associated protein 3
VEGFA vascular endothelial growth factor A
VGF VGF nerve growth factor inducible
WFDC2 WAP four-disulfide core domain 2
WNT6 wingless-type MMTV integration site family, member 6
YY1 YY1 transcription factor
ZNF227 zinc finger protein 227
ZNF573 zinc finger protein 573
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ACYP2 acylphosphatase 2, muscle type
AEN apoptosis enhancing nuclease
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANP32A-IT1 ANP32A intronic transcript 1
APOD apolipoprotein D
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATAD3A ATPase family, AAA domain containing 3A
BCL2L2 BCL2-like 2
C19ORF40 chromosome 19 open reading frame 40
CCDC9 coiled-coil domain containing 9
CCNL2 cyclin L2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CLCF1 cardiotrophin-like cytokine factor 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPTP ceramide-1-phosphate transfer protein
CRABP1 cellular retinoic acid binding protein 1
CRY2 cryptochrome circadian clock 2
CTAGE9 CTAGE family, member 9
CXORF56 chromosome X open reading frame 56
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
ECSIT ECSIT signalling integrator
EFNA3 ephrin-A3
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC4 histone deacetylase 4
IP6K2 inositol hexakisphosphate kinase 2
IRF9 interferon regulatory factor 9
IRX5 iroquois homeobox 5
JADE3 jade family PHD finger 3
KDM5C lysine (K)-specific demethylase 5C
KLHL36 kelch-like family member 36
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK3 mitogen-activated protein kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MON1B MON1 secretory trafficking family member B
MYL5 myosin, light chain 5, regulatory
MYO9A myosin IXA
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARD6A par-6 family cell polarity regulator alpha
PARG poly (ADP-ribose) glycohydrolase
PARP16 poly (ADP-ribose) polymerase family, member 16
PBLD phenazine biosynthesis-like protein domain containing
PDZRN3 PDZ domain containing ring finger 3
PES1 pescadillo ribosomal biogenesis factor 1
PP14571 uncharacterized LOC100130449
PTPRU protein tyrosine phosphatase, receptor type, U
PYCRL pyrroline-5-carboxylate reductase-like
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
S100A4 S100 calcium binding protein A4
SCUBE2 signal peptide, CUB domain, EGF-like 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SNAI2 snail family zinc finger 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX9 SRY (sex determining region Y)-box 9
SREBF1 sterol regulatory element binding transcription factor 1
STEAP3 STEAP family member 3, metalloreductase
SYCP2 synaptonemal complex protein 2
TBC1D17 TBC1 domain family, member 17
TBL3 transducin (beta)-like 3
THAP7 THAP domain containing 7
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM184C transmembrane protein 184C
TMEM2 transmembrane protein 2
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC23 tetratricopeptide repeat domain 23
TUBA3D tubulin, alpha 3d
TUBGCP5 tubulin, gamma complex associated protein 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC119 unc-119 homolog (C. elegans)
VEGFC vascular endothelial growth factor C
XKR8 XK, Kell blood group complex subunit-related family, member 8
XPC xeroderma pigmentosum, complementation group C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZMAT5 zinc finger, matrin-type 5
ZNF816 zinc finger protein 816
ZSCAN31 zinc finger and SCAN domain containing 31