valproic acid-1647 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the valproic acid-1647 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AKAP13 A kinase (PRKA) anchor protein 13
AMH anti-Mullerian hormone
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BRD4 bromodomain containing 4
CASKIN2 CASK interacting protein 2
CD79B CD79b molecule, immunoglobulin-associated beta
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK16 cyclin-dependent kinase 16
CLCA1 chloride channel accessory 1
CROCC ciliary rootlet coiled-coil, rootletin
CSNK1E casein kinase 1, epsilon
CST4 cystatin S
CXCR2 chemokine (C-X-C motif) receptor 2
CXORF21 chromosome X open reading frame 21
CYHR1 cysteine/histidine-rich 1
EGFL7 EGF-like-domain, multiple 7
EHD2 EH-domain containing 2
FAM134B family with sequence similarity 134, member B
FBXW12 F-box and WD repeat domain containing 12
FSCN1 fascin actin-bundling protein 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GRK5 G protein-coupled receptor kinase 5
GTPBP8 GTP-binding protein 8 (putative)
HAMP hepcidin antimicrobial peptide
HDLBP high density lipoprotein binding protein
HOMER3 homer scaffolding protein 3
HSF1 heat shock transcription factor 1
IGFALS insulin-like growth factor binding protein, acid labile subunit
IQSEC2 IQ motif and Sec7 domain 2
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD7 potassium channel tetramerization domain containing 7
KIAA0100 KIAA0100
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
LAMP1 lysosomal-associated membrane protein 1
LHX2 LIM homeobox 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MED25 mediator complex subunit 25
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPL52 mitochondrial ribosomal protein L52
MRPS12 mitochondrial ribosomal protein S12
MZT2B mitotic spindle organizing protein 2B
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NBL1 neuroblastoma 1, DAN family BMP antagonist
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
ONECUT2 one cut homeobox 2
OSBPL3 oxysterol binding protein-like 3
PDCD6 programmed cell death 6
PEX26 peroxisomal biogenesis factor 26
PICK1 protein interacting with PRKCA 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PKD1 polycystic kidney disease 1 (autosomal dominant)
PML promyelocytic leukemia
POMT2 protein-O-mannosyltransferase 2
POU2F2 POU class 2 homeobox 2
PRDX2 peroxiredoxin 2
PRR14L proline rich 14-like
PTCH1 patched 1
RANGAP1 Ran GTPase activating protein 1
RBM10 RNA binding motif protein 10
RNF2 ring finger protein 2
RNF208 ring finger protein 208
RPL13P5 ribosomal protein L13 pseudogene 5
RSU1 Ras suppressor protein 1
SASH1 SAM and SH3 domain containing 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SH3BP2 SH3-domain binding protein 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SOX4 SRY (sex determining region Y)-box 4
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX1A syntaxin 1A (brain)
SUGP1 SURP and G patch domain containing 1
SYMPK symplekin
SYT17 synaptotagmin XVII
TCF3 transcription factor 3
TMEM53 transmembrane protein 53
TNRC6B trinucleotide repeat containing 6B
TRIM2 tripartite motif containing 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USP12 ubiquitin specific peptidase 12
VPS9D1 VPS9 domain containing 1
VWA5A von Willebrand factor A domain containing 5A
WDR46 WD repeat domain 46
WNK1 WNK lysine deficient protein kinase 1
WSCD1 WSC domain containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZCCHC24 zinc finger, CCHC domain containing 24
ZER1 zyg-11 related, cell cycle regulator
ZNF419 zinc finger protein 419
ZNF444 zinc finger protein 444
ZNF580 zinc finger protein 580
ZNF721 zinc finger protein 721
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ADORA2B adenosine A2b receptor
AIDA axin interactor, dorsalization associated
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARRB2 arrestin, beta 2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAGE B melanoma antigen
BCAS4 breast carcinoma amplified sequence 4
BCL2L2 BCL2-like 2
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD2 BTB (POZ) domain containing 2
C1ORF56 chromosome 1 open reading frame 56
C5 complement component 5
CEPT1 choline/ethanolamine phosphotransferase 1
COMMD10 COMM domain containing 10
CPTP ceramide-1-phosphate transfer protein
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRIP2 cysteine-rich protein 2
CTSK cathepsin K
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCLRE1A DNA cross-link repair 1A
DDA1 DET1 and DDB1 associated 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERF Ets2 repressor factor
EXOC5 exocyst complex component 5
FNDC3B fibronectin type III domain containing 3B
FZD6 frizzled class receptor 6
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDE1 glycerophosphodiester phosphodiesterase 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH2 G patch domain containing 2
GPHN gephyrin
GTF2I general transcription factor IIi
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
H2BFS H2B histone family, member S (pseudogene)
HIRA histone cell cycle regulator
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ICK intestinal cell (MAK-like) kinase
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIF23 kinesin family member 23
KIFAP3 kinesin-associated protein 3
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
MAGEF1 melanoma antigen family F1
METTL2B methyltransferase like 2B
METTL8 methyltransferase like 8
MLF2 myeloid leukemia factor 2
MPDU1 mannose-P-dolichol utilization defect 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NHEJ1 nonhomologous end-joining factor 1
NNT nicotinamide nucleotide transhydrogenase
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PGD phosphogluconate dehydrogenase
PHACTR4 phosphatase and actin regulator 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POGK pogo transposable element with KRAB domain
PPAP2C phosphatidic acid phosphatase type 2C
PRPF39 pre-mRNA processing factor 39
PSENEN presenilin enhancer gamma secretase subunit
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PTER phosphotriesterase related
RWDD2A RWD domain containing 2A
SCAMP2 secretory carrier membrane protein 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SDAD1 SDA1 domain containing 1
SELT selenoprotein T
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2B3 SH2B adaptor protein 3
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SNIP1 Smad nuclear interacting protein 1
SNORA21 small nucleolar RNA, H/ACA box 21
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SYTL2 synaptotagmin-like 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN1 tectonic family member 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM106B transmembrane protein 106B
TMEM230 transmembrane protein 230
TMEM260 transmembrane protein 260
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA3D tubulin, alpha 3d
USP21 ubiquitin specific peptidase 21
YIPF5 Yip1 domain family, member 5
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF586 zinc finger protein 586