valproic acid-23 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the valproic acid-23 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
AHNAK2 AHNAK nucleoprotein 2
ALAD aminolevulinate dehydratase
AMBRA1 autophagy/beclin-1 regulator 1
ASF1A anti-silencing function 1A histone chaperone
ATOX1 antioxidant 1 copper chaperone
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BCL6 B-cell CLL/lymphoma 6
BCORL1 BCL6 corepressor-like 1
C9ORF16 chromosome 9 open reading frame 16
CDK5 cyclin-dependent kinase 5
CHN1 chimerin 1
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIC capicua transcriptional repressor
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CPTP ceramide-1-phosphate transfer protein
CSRP2 cysteine and glycine-rich protein 2
CUL4B cullin 4B
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DND1 DND microRNA-mediated repression inhibitor 1
DUS2 dihydrouridine synthase 2
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EHD2 EH-domain containing 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENO2 enolase 2 (gamma, neuronal)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTPBP2 GTP binding protein 2
GYG2 glycogenin 2
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HLA-G major histocompatibility complex, class I, G
HMOX2 heme oxygenase 2
HSPA13 heat shock protein 70kDa family, member 13
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFFO1 intermediate filament family orphan 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF5C kinesin family member 5C
L1CAM L1 cell adhesion molecule
LGMN legumain
MAP1B microtubule-associated protein 1B
MARK2 MAP/microtubule affinity-regulating kinase 2
MED8 mediator complex subunit 8
MKRN1 makorin ring finger protein 1
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MNAT1 MNAT CDK-activating kinase assembly factor 1
MOB3B MOB kinase activator 3B
MRPS31 mitochondrial ribosomal protein S31
MT1F metallothionein 1F
MTSS1 metastasis suppressor 1
MXRA7 matrix-remodelling associated 7
MYO6 myosin VI
NES nestin
PADI1 peptidyl arginine deiminase, type I
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G16 phospholipase A2, group XVI
PLCD1 phospholipase C, delta 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPME1 protein phosphatase methylesterase 1
PRAF2 PRA1 domain family, member 2
PRRC2A proline-rich coiled-coil 2A
PTRF polymerase I and transcript release factor
RAB29 RAB29, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
REEP1 receptor accessory protein 1
RHOQ ras homolog family member Q
RRAGD Ras-related GTP binding D
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
SASH1 SAM and SH3 domain containing 1
SEC23B Sec23 homolog B (S. cerevisiae)
SEZ6L seizure related 6 homolog (mouse)-like
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
TBL1X transducin (beta)-like 1X-linked
TCEA2 transcription elongation factor A (SII), 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TUBA3C tubulin, alpha 3c
TUBB2A tubulin, beta 2A class IIa
ULBP2 UL16 binding protein 2
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WRAP53 WD repeat containing, antisense to TP53
WWOX WW domain containing oxidoreductase
YLPM1 YLP motif containing 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF443 zinc finger protein 443

decreased expression

Symbol Name
ADORA3 adenosine A3 receptor
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATXN8OS ATXN8 opposite strand (non-protein coding)
BAGE B melanoma antigen
BBC3 BCL2 binding component 3
BNC2 basonuclin 2
C1ORF54 chromosome 1 open reading frame 54
C1ORF95 chromosome 1 open reading frame 95
C2CD5 C2 calcium-dependent domain containing 5
C2ORF54 chromosome 2 open reading frame 54
C4ORF29 chromosome 4 open reading frame 29
C6 complement component 6
CBLN1 cerebellin 1 precursor
CCDC87 coiled-coil domain containing 87
CD5 CD5 molecule
CEP72 centrosomal protein 72kDa
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHKB choline kinase beta
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
COIL coilin
CRYAA crystallin, alpha A
CTPS1 CTP synthase 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DUSP12 dual specificity phosphatase 12
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF22 fibroblast growth factor 22
FGF7 fibroblast growth factor 7
FGR FGR proto-oncogene, Src family tyrosine kinase
FJX1 four jointed box 1 (Drosophila)
FOXC1 forkhead box C1
FURIN furin (paired basic amino acid cleaving enzyme)
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GK2 glycerol kinase 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HOXC4 homeobox C4
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNG interferon, gamma
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL13 interleukin 13
IL7R interleukin 7 receptor
KIF20B kinesin family member 20B
KIF4A kinesin family member 4A
LAS1L LAS1-like (S. cerevisiae)
LECT1 leukocyte cell derived chemotaxin 1
LIM2 lens intrinsic membrane protein 2, 19kDa
LMNB1 lamin B1
MED31 mediator complex subunit 31
NCAPH non-SMC condensin I complex, subunit H
NEUROD4 neuronal differentiation 4
NPFFR1 neuropeptide FF receptor 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR2H1 olfactory receptor, family 2, subfamily H, member 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHGA1 protocadherin gamma subfamily A, 1
PFAS phosphoribosylformylglycinamidine synthase
PHOX2B paired-like homeobox 2b
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PPAN peter pan homolog (Drosophila)
PPCDC phosphopantothenoylcysteine decarboxylase
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRSS2 protease, serine, 2 (trypsin 2)
PSG11 pregnancy specific beta-1-glycoprotein 11
PTPRT protein tyrosine phosphatase, receptor type, T
PXDC1 PX domain containing 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF141 ring finger protein 141
RXRG retinoid X receptor, gamma
SCAF8 SR-related CTD-associated factor 8
SCIN scinderin
SETD1A SET domain containing 1A
SIRT7 sirtuin 7
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SRBD1 S1 RNA binding domain 1
STAB2 stabilin 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM187 transmembrane protein 187
TSPAN5 tetraspanin 5
TYR tyrosinase
UNG uracil-DNA glycosylase
VIM vimentin
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB16 zinc finger and BTB domain containing 16
ZNF516 zinc finger protein 516
ZNF652 zinc finger protein 652