valproic acid-2674 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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192 genes differentially expressed following the valproic acid-2674 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACAA2 acetyl-CoA acyltransferase 2
ANG angiogenin, ribonuclease, RNase A family, 5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARG2 arginase 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BIK BCL2-interacting killer (apoptosis-inducing)
BIN1 bridging integrator 1
BMP7 bone morphogenetic protein 7
CCDC57 coiled-coil domain containing 57
CD70 CD70 molecule
CDC14A cell division cycle 14A
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP295 centrosomal protein 295kDa
CPM carboxypeptidase M
CRAT carnitine O-acetyltransferase
CRP C-reactive protein, pentraxin-related
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGKG diacylglycerol kinase, gamma 90kDa
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOPEY2 dopey family member 2
DPP4 dipeptidyl-peptidase 4
DSP desmoplakin
ECI2 enoyl-CoA delta isomerase 2
EXT1 exostosin glycosyltransferase 1
F11R F11 receptor
FABP7 fatty acid binding protein 7, brain
FAM49A family with sequence similarity 49, member A
FGF3 fibroblast growth factor 3
FKBP1B FK506 binding protein 1B, 12.6 kDa
GCH1 GTP cyclohydrolase 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIPR gastric inhibitory polypeptide receptor
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRPR gastrin-releasing peptide receptor
HEMK1 HemK methyltransferase family member 1
HOXA7 homeobox A7
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV3-19 immunoglobulin lambda variable 3-19
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
LPAR6 lysophosphatidic acid receptor 6
LPPR2 lipid phosphate phosphatase-related protein type 2
MAB21L1 mab-21-like 1 (C. elegans)
MAMLD1 mastermind-like domain containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MMRN2 multimerin 2
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MPZL1 myelin protein zero-like 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTUS1 microtubule associated tumor suppressor 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYO10 myosin X
NCAM1 neural cell adhesion molecule 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NYNRIN NYN domain and retroviral integrase containing
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRL platelet-derived growth factor receptor-like
PDLIM5 PDZ and LIM domain 5
PFN2 profilin 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PKP1 plakophilin 1
PMP22 peripheral myelin protein 22
POU4F1 POU class 4 homeobox 1
PRELP proline/arginine-rich end leucine-rich repeat protein
PROX1 prospero homeobox 1
PRSS23 protease, serine, 23
RAB26 RAB26, member RAS oncogene family
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
STON1 stonin 1
SYNM synemin, intermediate filament protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESK1 testis-specific kinase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBR3 transforming growth factor, beta receptor III
TPMT thiopurine S-methyltransferase
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM2 tripartite motif containing 2
TRO trophinin
TSHB thyroid stimulating hormone, beta
TUBB2A tubulin, beta 2A class IIa
WTAP Wilms tumor 1 associated protein
ZBTB7C zinc finger and BTB domain containing 7C
ZC3H13 zinc finger CCCH-type containing 13

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADGB androglobin
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARMCX4 armadillo repeat containing, X-linked 4
BBC3 BCL2 binding component 3
C14ORF93 chromosome 14 open reading frame 93
C19ORF73 chromosome 19 open reading frame 73
C8A complement component 8, alpha polypeptide
C8ORF44 chromosome 8 open reading frame 44
C9ORF9 chromosome 9 open reading frame 9
CD79B CD79b molecule, immunoglobulin-associated beta
CDA cytidine deaminase
CFP complement factor properdin
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
COL4A2 collagen, type IV, alpha 2
CPNE7 copine VII
CXORF56 chromosome X open reading frame 56
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DPEP2 dipeptidase 2
DUSP2 dual specificity phosphatase 2
ECSIT ECSIT signalling integrator
ELAC1 elaC ribonuclease Z 1
EPHB6 EPH receptor B6
F13A1 coagulation factor XIII, A1 polypeptide
FMOD fibromodulin
FZD4 frizzled class receptor 4
GID4 GID complex subunit 4
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRB7 growth factor receptor-bound protein 7
HCFC1 host cell factor C1
HIST1H2BE histone cluster 1, H2be
HIST1H2BN histone cluster 1, H2bn
HIST1H4J histone cluster 1, H4j
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
INHBE inhibin, beta E
JUNB jun B proto-oncogene
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KLK5 kallikrein-related peptidase 5
LOXL3 lysyl oxidase-like 3
LTB lymphotoxin beta (TNF superfamily, member 3)
MAGEB2 melanoma antigen family B2
MAGEF1 melanoma antigen family F1
MBD5 methyl-CpG binding domain protein 5
MEPCE methylphosphate capping enzyme
METTL21B methyltransferase like 21B
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP9 matrix metallopeptidase 9
MRAS muscle RAS oncogene homolog
MTMR11 myotubularin related protein 11
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXF2 nuclear RNA export factor 2
OVGP1 oviductal glycoprotein 1, 120kDa
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMF1 polyamine-modulated factor 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
PYCRL pyrroline-5-carboxylate reductase-like
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SH2D4A SH2 domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPRYD7 SPRY domain containing 7
STAB2 stabilin 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THBS4 thrombospondin 4
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM242 transmembrane protein 242
TUBA3C tubulin, alpha 3c
UPK3A uroplakin 3A
USP36 ubiquitin specific peptidase 36
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR62 WD repeat domain 62
YY2 YY2 transcription factor
ZNF219 zinc finger protein 219
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768
ZNF816 zinc finger protein 816
ZNHIT2 zinc finger, HIT-type containing 2