valproic acid-2700 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the valproic acid-2700 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ACSM1 acyl-CoA synthetase medium-chain family member 1
AIM2 absent in melanoma 2
ALOX5 arachidonate 5-lipoxygenase
AMH anti-Mullerian hormone
ANG angiogenin, ribonuclease, RNase A family, 5
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ASPH aspartate beta-hydroxylase
BTF3P11 basic transcription factor 3 pseudogene 11
C1R complement component 1, r subcomponent
C3ORF14 chromosome 3 open reading frame 14
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CALD1 caldesmon 1
CCDC87 coiled-coil domain containing 87
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELA2A chymotrypsin-like elastase family, member 2A
COL1A2 collagen, type I, alpha 2
COL9A3 collagen, type IX, alpha 3
CREB3L1 cAMP responsive element binding protein 3-like 1
CSRP2 cysteine and glycine-rich protein 2
DNAH17 dynein, axonemal, heavy chain 17
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNALI1 dynein, axonemal, light intermediate chain 1
DPP4 dipeptidyl-peptidase 4
EPAS1 endothelial PAS domain protein 1
FAM149A family with sequence similarity 149, member A
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALR2 galanin receptor 2
GCH1 GTP cyclohydrolase 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRPR gastrin-releasing peptide receptor
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA7 homeobox A7
HOXD13 homeobox D13
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI16 interferon, gamma-inducible protein 16
IFNA8 interferon, alpha 8
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGSF1 immunoglobulin superfamily, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
LHX2 LIM homeobox 2
LOXL1 lysyl oxidase-like 1
LRRC75B leucine rich repeat containing 75B
LTA lymphotoxin alpha
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MOBP myelin-associated oligodendrocyte basic protein
MYH11 myosin, heavy chain 11, smooth muscle
NPTXR neuronal pentraxin receptor
NRG2 neuregulin 2
NUDC nudC nuclear distribution protein
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OSBP2 oxysterol binding protein 2
OTOF otoferlin
PAPOLB poly(A) polymerase beta (testis specific)
PAX8 paired box 8
PBOV1 prostate and breast cancer overexpressed 1
PDE4DIP phosphodiesterase 4D interacting protein
PFN2 profilin 2
POU4F1 POU class 4 homeobox 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB3 proline-rich protein BstNI subfamily 3
PVR poliovirus receptor
RAB26 RAB26, member RAS oncogene family
RAD51B RAD51 paralog B
RAG2 recombination activating gene 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFPL1 ret finger protein-like 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SCGB2A1 secretoglobin, family 2A, member 1
SH3D21 SH3 domain containing 21
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SPATA2L spermatogenesis associated 2-like
SPON1 spondin 1, extracellular matrix protein
STON1 stonin 1
SUGCT succinyl-CoA:glutarate-CoA transferase
SULF1 sulfatase 1
SYT5 synaptotagmin V
TBX1 T-box 1
TK2 thymidine kinase 2, mitochondrial
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRO trophinin
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TSPYL5 TSPY-like 5
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
UBASH3A ubiquitin associated and SH3 domain containing A
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
ULBP2 UL16 binding protein 2
VENTX VENT homeobox
WNT1 wingless-type MMTV integration site family, member 1

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADI1 acireductone dioxygenase 1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANKRD55 ankyrin repeat domain 55
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BBC3 BCL2 binding component 3
BPHL biphenyl hydrolase-like (serine hydrolase)
C3 complement component 3
C8ORF44 chromosome 8 open reading frame 44
CCL27 chemokine (C-C motif) ligand 27
CD79B CD79b molecule, immunoglobulin-associated beta
CDK3 cyclin-dependent kinase 3
CLCF1 cardiotrophin-like cytokine factor 1
CLEC2D C-type lectin domain family 2, member D
CNR2 cannabinoid receptor 2 (macrophage)
COL15A1 collagen, type XV, alpha 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXORF56 chromosome X open reading frame 56
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHODH dihydroorotate dehydrogenase (quinone)
DUSP2 dual specificity phosphatase 2
ETV6 ets variant 6
FADS2 fatty acid desaturase 2
FOXN2 forkhead box N2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
H2BFS H2B histone family, member S (pseudogene)
HIST1H1E histone cluster 1, H1e
HIST1H2AM histone cluster 1, H2am
HIST1H2BI histone cluster 1, H2bi
HSPA1L heat shock 70kDa protein 1-like
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IDI2-AS1 IDI2 antisense RNA 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KATNBL1 katanin p80 subunit B-like 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1024 KIAA1024
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
LIMD2 LIM domain containing 2
LY6E lymphocyte antigen 6 complex, locus E
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCRS1 microspherule protein 1
METTL16 methyltransferase like 16
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP9 matrix metallopeptidase 9
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX26 peroxisomal biogenesis factor 26
PIR pirin (iron-binding nuclear protein)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PMF1 polyamine-modulated factor 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PRF1 perforin 1 (pore forming protein)
PRR4 proline rich 4 (lacrimal)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
SARS2 seryl-tRNA synthetase 2, mitochondrial
SDF2 stromal cell-derived factor 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLPI secretory leukocyte peptidase inhibitor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SYNJ2BP synaptojanin 2 binding protein
THBS3 thrombospondin 3
THBS4 thrombospondin 4
THRAP3 thyroid hormone receptor associated protein 3
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TONSL tonsoku-like, DNA repair protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TXLNG taxilin gamma
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
USP21 ubiquitin specific peptidase 21
VN1R1 vomeronasal 1 receptor 1
VNN2 vanin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR33 WD repeat domain 33
WDR6 WD repeat domain 6
ZMAT5 zinc finger, matrin-type 5
ZNF155 zinc finger protein 155
ZNF16 zinc finger protein 16
ZNF33B zinc finger protein 33B
ZNF473 zinc finger protein 473
ZNF768 zinc finger protein 768
ZNHIT2 zinc finger, HIT-type containing 2