valproic acid-345 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the valproic acid-345 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHCYL2 adenosylhomocysteinase-like 2
AHNAK2 AHNAK nucleoprotein 2
AMT aminomethyltransferase
AQP3 aquaporin 3 (Gill blood group)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
BIK BCL2-interacting killer (apoptosis-inducing)
BMP7 bone morphogenetic protein 7
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C7ORF43 chromosome 7 open reading frame 43
CCNG2 cyclin G2
CD2 CD2 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFAP70 cilia and flagella associated protein 70
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRM4 cholinergic receptor, muscarinic 4
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COPZ2 coatomer protein complex, subunit zeta 2
CORO1A coronin, actin binding protein, 1A
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DBP D site of albumin promoter (albumin D-box) binding protein
DENND3 DENN/MADD domain containing 3
DLX2 distal-less homeobox 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EFNA3 ephrin-A3
EXTL2 exostosin-like glycosyltransferase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM50B family with sequence similarity 50, member B
FAM89B family with sequence similarity 89, member B
FGD6 FYVE, RhoGEF and PH domain containing 6
FGFR1 fibroblast growth factor receptor 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GRB10 growth factor receptor-bound protein 10
GUCA1B guanylate cyclase activator 1B (retina)
GYPB glycophorin B (MNS blood group)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
INSIG2 insulin induced gene 2
KIF5C kinesin family member 5C
KIFAP3 kinesin-associated protein 3
LARP7 La ribonucleoprotein domain family, member 7
LBP lipopolysaccharide binding protein
LDLRAP1 low density lipoprotein receptor adaptor protein 1
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
MMD monocyte to macrophage differentiation-associated
MYL10 myosin, light chain 10, regulatory
N4BP2L2 NEDD4 binding protein 2-like 2
OASL 2'-5'-oligoadenylate synthetase-like
PDE4A phosphodiesterase 4A, cAMP-specific
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPARD peroxisome proliferator-activated receptor delta
RAB29 RAB29, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RIPK4 receptor-interacting serine-threonine kinase 4
RNF24 ring finger protein 24
RRBP1 ribosome binding protein 1
RTN2 reticulon 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SERINC5 serine incorporator 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAI1 snail family zinc finger 1
SNN stannin
SOD2 superoxide dismutase 2, mitochondrial
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STON1 stonin 1
STX12 syntaxin 12
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIM2 tripartite motif containing 2
TSC2 tuberous sclerosis 2
TULP3 tubby like protein 3
TXNIP thioredoxin interacting protein
UBE4B ubiquitination factor E4B
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF324 zinc finger protein 324
ZNF365 zinc finger protein 365
ZNF394 zinc finger protein 394
ZNF589 zinc finger protein 589
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
AXIN1 axin 1
BAGE B melanoma antigen
BHMT betaine--homocysteine S-methyltransferase
C1ORF159 chromosome 1 open reading frame 159
CA11 carbonic anhydrase XI
CAV3 caveolin 3
CBR3 carbonyl reductase 3
CCL21 chemokine (C-C motif) ligand 21
CCNL2 cyclin L2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CLCF1 cardiotrophin-like cytokine factor 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNTD2 cyclin N-terminal domain containing 2
COIL coilin
CRYM crystallin, mu
CTNNBIP1 catenin, beta interacting protein 1
DAGLA diacylglycerol lipase, alpha
DENND2D DENN/MADD domain containing 2D
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP22 dual specificity phosphatase 22
EGR3 early growth response 3
ELP6 elongator acetyltransferase complex subunit 6
EPHA4 EPH receptor A4
ESRP2 epithelial splicing regulatory protein 2
EVPL envoplakin
EXOC3 exocyst complex component 3
FAM110D family with sequence similarity 110, member D
FAM192A family with sequence similarity 192, member A
FJX1 four jointed box 1 (Drosophila)
FOLR2 folate receptor 2 (fetal)
FOXC1 forkhead box C1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GATA3 GATA binding protein 3
GLRA2 glycine receptor, alpha 2
GMIP GEM interacting protein
GRWD1 glutamate-rich WD repeat containing 1
HDAC11 histone deacetylase 11
HIRIP3 HIRA interacting protein 3
HIST1H4J histone cluster 1, H4j
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
KDM5D lysine (K)-specific demethylase 5D
KEAP1 kelch-like ECH-associated protein 1
KLHL3 kelch-like family member 3
KRI1 KRI1 homolog (S. cerevisiae)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MEPCE methylphosphate capping enzyme
MEPE matrix extracellular phosphoglycoprotein
MEX3C mex-3 RNA binding family member C
MRPL35 mitochondrial ribosomal protein L35
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NMD3 NMD3 ribosome export adaptor
NNAT neuronatin
NUP62 nucleoporin 62kDa
PCDHB6 protocadherin beta 6
PLCD1 phospholipase C, delta 1
POGLUT1 protein O-glucosyltransferase 1
PPCDC phosphopantothenoylcysteine decarboxylase
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRDM14 PR domain containing 14
PRMT3 protein arginine methyltransferase 3
PTPN7 protein tyrosine phosphatase, non-receptor type 7
QTRT1 queuine tRNA-ribosyltransferase 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM10 RNA binding motif protein 10
RHOH ras homolog family member H
SCAF8 SR-related CTD-associated factor 8
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1A SET domain containing 1A
SETD1B SET domain containing 1B
SLC10A3 solute carrier family 10, member 3
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG9 SMG9 nonsense mediated mRNA decay factor
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SOAT2 sterol O-acyltransferase 2
SREK1 splicing regulatory glutamine/lysine-rich protein 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STC2 stanniocalcin 2
TCEA2 transcription elongation factor A (SII), 2
TDRD12 tudor domain containing 12
TGIF1 TGFB-induced factor homeobox 1
TNNI3 troponin I type 3 (cardiac)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSPAN15 tetraspanin 15
URGCP upregulator of cell proliferation
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR13 WD repeat domain 13
XBP1 X-box binding protein 1
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1