valproic acid-346 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the valproic acid-346 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADK adenosine kinase
AGTPBP1 ATP/GTP binding protein 1
AHNAK2 AHNAK nucleoprotein 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
AVPR1B arginine vasopressin receptor 1B
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BEX4 brain expressed, X-linked 4
BMP7 bone morphogenetic protein 7
C7ORF43 chromosome 7 open reading frame 43
CA1 carbonic anhydrase I
CCDC68 coiled-coil domain containing 68
CCDC85C coiled-coil domain containing 85C
CCNG2 cyclin G2
CD93 CD93 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CFAP70 cilia and flagella associated protein 70
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COPZ2 coatomer protein complex, subunit zeta 2
CORO1A coronin, actin binding protein, 1A
CPNE7 copine VII
CYLD cylindromatosis (turban tumor syndrome)
DIXDC1 DIX domain containing 1
DXO decapping exoribonuclease
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EFR3B EFR3 homolog B (S. cerevisiae)
ELOVL4 ELOVL fatty acid elongase 4
FAM50B family with sequence similarity 50, member B
FAM89B family with sequence similarity 89, member B
FANCA Fanconi anemia, complementation group A
FGD6 FYVE, RhoGEF and PH domain containing 6
FGFR1 fibroblast growth factor receptor 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GLRX glutaredoxin (thioltransferase)
HOXC10 homeobox C10
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFNA14 interferon, alpha 14
IGHMBP2 immunoglobulin mu binding protein 2
IL1B interleukin 1, beta
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
KIF5C kinesin family member 5C
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KREMEN2 kringle containing transmembrane protein 2
LARP7 La ribonucleoprotein domain family, member 7
MAP2K4 mitogen-activated protein kinase kinase 4
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MST1R macrophage stimulating 1 receptor
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2 NEDD4 binding protein 2-like 2
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NADK NAD kinase
NOTCH3 notch 3
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRP2 neuropilin 2
OASL 2'-5'-oligoadenylate synthetase-like
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11Y protocadherin 11 Y-linked
PCP4 Purkinje cell protein 4
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PEX11A peroxisomal biogenesis factor 11 alpha
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
RAB29 RAB29, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RIPK4 receptor-interacting serine-threonine kinase 4
RTN2 reticulon 2
SDC2 syndecan 2
SERINC5 serine incorporator 5
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SNTA1 syntrophin, alpha 1
SPEF1 sperm flagellar 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYBU syntabulin (syntaxin-interacting)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM121 transmembrane protein 121
TMEM159 transmembrane protein 159
TMEM50A transmembrane protein 50A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM2 tripartite motif containing 2
TSC2 tuberous sclerosis 2
TULP3 tubby like protein 3
UBE4B ubiquitination factor E4B
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WRB tryptophan rich basic protein
ZNF589 zinc finger protein 589
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
APOH apolipoprotein H (beta-2-glycoprotein I)
APOLD1 apolipoprotein L domain containing 1
AQP8 aquaporin 8
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARSF arylsulfatase F
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BANP BTG3 associated nuclear protein
BATF3 basic leucine zipper transcription factor, ATF-like 3
BBC3 BCL2 binding component 3
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BHMT betaine--homocysteine S-methyltransferase
BMPR1B bone morphogenetic protein receptor, type IB
BTBD2 BTB (POZ) domain containing 2
C14ORF79 chromosome 14 open reading frame 79
C1ORF109 chromosome 1 open reading frame 109
C2CD5 C2 calcium-dependent domain containing 5
CCDC170 coiled-coil domain containing 170
CCL19 chemokine (C-C motif) ligand 19
CCL22 chemokine (C-C motif) ligand 22
CCNL2 cyclin L2
CD5 CD5 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHIA chitinase, acidic
CNTD2 cyclin N-terminal domain containing 2
COQ4 coenzyme Q4
CTNNBIP1 catenin, beta interacting protein 1
DENND2D DENN/MADD domain containing 2D
DGAT1 diacylglycerol O-acyltransferase 1
DIO3 deiodinase, iodothyronine, type III
ESRP2 epithelial splicing regulatory protein 2
EVPL envoplakin
FGFBP1 fibroblast growth factor binding protein 1
FKBP10 FK506 binding protein 10, 65 kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
HDAC11 histone deacetylase 11
HIRIP3 HIRA interacting protein 3
HIST1H4J histone cluster 1, H4j
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL15RA interleukin 15 receptor, alpha
IMPACT impact RWD domain protein
IRX4 iroquois homeobox 4
KDM5D lysine (K)-specific demethylase 5D
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0430 KIAA0430
KRI1 KRI1 homolog (S. cerevisiae)
MBD3 methyl-CpG binding domain protein 3
MEPE matrix extracellular phosphoglycoprotein
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MS4A12 membrane-spanning 4-domains, subfamily A, member 12
MYO1F myosin IF
NARFL nuclear prelamin A recognition factor-like
NOD1 nucleotide-binding oligomerization domain containing 1
NPPA natriuretic peptide A
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVOL1 ovo-like zinc finger 1
PADI1 peptidyl arginine deiminase, type I
PCDHB6 protocadherin beta 6
PFDN1 prefoldin subunit 1
PISD phosphatidylserine decarboxylase
POGLUT1 protein O-glucosyltransferase 1
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PQLC3 PQ loop repeat containing 3
PRDM14 PR domain containing 14
PTPN7 protein tyrosine phosphatase, non-receptor type 7
REC8 REC8 meiotic recombination protein
RHOBTB1 Rho-related BTB domain containing 1
RNF141 ring finger protein 141
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1A SET domain containing 1A
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMA4 glucuronidase, beta pseudogene
SMYD5 SMYD family member 5
SOAT2 sterol O-acyltransferase 2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST7L suppression of tumorigenicity 7 like
SUN2 Sad1 and UNC84 domain containing 2
TCEA2 transcription elongation factor A (SII), 2
TDRD12 tudor domain containing 12
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS4 thrombospondin 4
TNNI3 troponin I type 3 (cardiac)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPAN15 tetraspanin 15
UBE2O ubiquitin-conjugating enzyme E2O
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR13 WD repeat domain 13
ZIC1 Zic family member 1
ZNF74 zinc finger protein 74
ZXDC ZXD family zinc finger C