valproic acid-348 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the valproic acid-348 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADK adenosine kinase
ALLC allantoicase
ALS2CL ALS2 C-terminal like
AMN amnion associated transmembrane protein
AMT aminomethyltransferase
ANK2 ankyrin 2, neuronal
AURKA aurora kinase A
BAIAP2 BAI1-associated protein 2
CA5A carbonic anhydrase VA, mitochondrial
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CD209 CD209 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CORO1B coronin, actin binding protein, 1B
CPNE7 copine VII
DXO decapping exoribonuclease
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EFR3B EFR3 homolog B (S. cerevisiae)
EID1 EP300 interacting inhibitor of differentiation 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV1 ets variant 1
EXOC6B exocyst complex component 6B
F8 coagulation factor VIII, procoagulant component
FAM50B family with sequence similarity 50, member B
FAM89B family with sequence similarity 89, member B
FANCA Fanconi anemia, complementation group A
FCAR Fc fragment of IgA receptor
FGFR1 fibroblast growth factor receptor 1
GAST gastrin
GLIPR1 GLI pathogenesis-related 1
GREB1L growth regulation by estrogen in breast cancer-like
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HBS1L HBS1-like translational GTPase
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HOXC10 homeobox C10
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICAM1 intercellular adhesion molecule 1
JAKMIP2 janus kinase and microtubule interacting protein 2
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LARP7 La ribonucleoprotein domain family, member 7
LEMD3 LEM domain containing 3
LINC00216 long intergenic non-protein coding RNA 216
LINC00574 long intergenic non-protein coding RNA 574
MEGF6 multiple EGF-like-domains 6
MOG myelin oligodendrocyte glycoprotein
MPPE1 metallophosphoesterase 1
MPZL1 myelin protein zero-like 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO15B myosin XVB
N4BP2L2 NEDD4 binding protein 2-like 2
NCR2 natural cytotoxicity triggering receptor 2
NLE1 notchless homolog 1 (Drosophila)
NOP16 NOP16 nucleolar protein
NR1I2 nuclear receptor subfamily 1, group I, member 2
NUP160 nucleoporin 160kDa
OASL 2'-5'-oligoadenylate synthetase-like
PCP4 Purkinje cell protein 4
PDE7B phosphodiesterase 7B
PDLIM7 PDZ and LIM domain 7 (enigma)
PIGR polymeric immunoglobulin receptor
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PKN2 protein kinase N2
PON1 paraoxonase 1
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRELP proline/arginine-rich end leucine-rich repeat protein
PTBP2 polypyrimidine tract binding protein 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGSL1 regulator of G-protein signaling like 1
RIPK4 receptor-interacting serine-threonine kinase 4
RPL15 ribosomal protein L15
RPL23AP32 ribosomal protein L23a pseudogene 32
RRBP1 ribosome binding protein 1
RUNDC3A RUN domain containing 3A
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERINC5 serine incorporator 5
SEZ6L seizure related 6 homolog (mouse)-like
SLC17A4 solute carrier family 17, member 4
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SNX19 sorting nexin 19
SOD2 superoxide dismutase 2, mitochondrial
SPON2 spondin 2, extracellular matrix protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM50A transmembrane protein 50A
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRIM2 tripartite motif containing 2
UBE4B ubiquitination factor E4B
WDR18 WD repeat domain 18
ZFAND6 zinc finger, AN1-type domain 6
ZNF460 zinc finger protein 460
ZNF589 zinc finger protein 589
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
APOLD1 apolipoprotein L domain containing 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
AXIN1 axin 1
BCL9 B-cell CLL/lymphoma 9
BMPR1B bone morphogenetic protein receptor, type IB
C16ORF59 chromosome 16 open reading frame 59
C8B complement component 8, beta polypeptide
CAV3 caveolin 3
CCL19 chemokine (C-C motif) ligand 19
CCL21 chemokine (C-C motif) ligand 21
CCL22 chemokine (C-C motif) ligand 22
CD5 CD5 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK11A cyclin-dependent kinase 11A
CDK5 cyclin-dependent kinase 5
CENPO centromere protein O
CHGB chromogranin B
CHIA chitinase, acidic
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTNNBIP1 catenin, beta interacting protein 1
DAGLA diacylglycerol lipase, alpha
DGAT1 diacylglycerol O-acyltransferase 1
DIO3 deiodinase, iodothyronine, type III
DSE dermatan sulfate epimerase
DTX2 deltex 2, E3 ubiquitin ligase
EFCAB1 EF-hand calcium binding domain 1
EVI2B ecotropic viral integration site 2B
EVPL envoplakin
FAM110D family with sequence similarity 110, member D
FKBP10 FK506 binding protein 10, 65 kDa
FOLR2 folate receptor 2 (fetal)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FXYD6 FXYD domain containing ion transport regulator 6
GAL3ST4 galactose-3-O-sulfotransferase 4
GMIP GEM interacting protein
HDAC11 histone deacetylase 11
HIST1H3I histone cluster 1, H3i
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMHA1 histocompatibility (minor) HA-1
HMX1 H6 family homeobox 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KDM5D lysine (K)-specific demethylase 5D
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLHL11 kelch-like family member 11
KLHL25 kelch-like family member 25
KRI1 KRI1 homolog (S. cerevisiae)
KRT32 keratin 32, type I
LZTS3 leucine zipper, putative tumor suppressor family member 3
MEPE matrix extracellular phosphoglycoprotein
NNAT neuronatin
NPTX1 neuronal pentraxin I
PCDHB6 protocadherin beta 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE12 phosphodiesterase 12
PMEL premelanosome protein
POGLUT1 protein O-glucosyltransferase 1
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PQLC3 PQ loop repeat containing 3
PRDM14 PR domain containing 14
PRF1 perforin 1 (pore forming protein)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
SCNN1B sodium channel, non voltage gated 1 beta subunit
SETD1A SET domain containing 1A
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35E3 solute carrier family 35, member E3
SMYD5 SMYD family member 5
SOAT2 sterol O-acyltransferase 2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SQRDL sulfide quinone reductase-like (yeast)
SSTR4 somatostatin receptor 4
ST7L suppression of tumorigenicity 7 like
SUSD4 sushi domain containing 4
TCEA2 transcription elongation factor A (SII), 2
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TDRD12 tudor domain containing 12
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
THBS4 thrombospondin 4
TMEM242 transmembrane protein 242
TREM1 triggering receptor expressed on myeloid cells 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPAN32 tetraspanin 32
UBE2O ubiquitin-conjugating enzyme E2O
USP27X ubiquitin specific peptidase 27, X-linked
VIM vimentin
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR19 WD repeat domain 19
XYLT1 xylosyltransferase I
ZNF702P zinc finger protein 702, pseudogene
ZXDC ZXD family zinc finger C