valproic acid-410 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the valproic acid-410 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
AGFG2 ArfGAP with FG repeats 2
ASMTL acetylserotonin O-methyltransferase-like
ATG4B autophagy related 4B, cysteine peptidase
ATP13A2 ATPase type 13A2
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C2CD2L C2CD2-like
C5ORF45 chromosome 5 open reading frame 45
C6ORF106 chromosome 6 open reading frame 106
CAMLG calcium modulating ligand
CCNG2 cyclin G2
CCSER2 coiled-coil serine-rich protein 2
CHERP calcium homeostasis endoplasmic reticulum protein
CLCN3 chloride channel, voltage-sensitive 3
CREB3 cAMP responsive element binding protein 3
CYLD cylindromatosis (turban tumor syndrome)
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDAH2 dimethylarginine dimethylaminohydrolase 2
ECI2 enoyl-CoA delta isomerase 2
EFCAB11 EF-hand calcium binding domain 11
EFNA3 ephrin-A3
EFNB3 ephrin-B3
FAM131A family with sequence similarity 131, member A
FGFR1 fibroblast growth factor receptor 1
GCAT glycine C-acetyltransferase
GM2A GM2 ganglioside activator
GRK5 G protein-coupled receptor kinase 5
GSK3A glycogen synthase kinase 3 alpha
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
H1F0 H1 histone family, member 0
HSPA13 heat shock protein 70kDa family, member 13
IER5 immediate early response 5
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT20 intraflagellar transport 20
ITSN1 intersectin 1 (SH3 domain protein)
JOSD1 Josephin domain containing 1
JUP junction plakoglobin
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF21B kinesin family member 21B
KLC2 kinesin light chain 2
KLHL26 kelch-like family member 26
LMAN2L lectin, mannose-binding 2-like
LONP2 lon peptidase 2, peroxisomal
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC42 leucine rich repeat containing 42
MAGEF1 melanoma antigen family F1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MCOLN1 mucolipin 1
MFSD12 major facilitator superfamily domain containing 12
MICB MHC class I polypeptide-related sequence B
MPPE1 metallophosphoesterase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
N4BP1 NEDD4 binding protein 1
NCOA3 nuclear receptor coactivator 3
NRGN neurogranin (protein kinase C substrate, RC3)
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OVGP1 oviductal glycoprotein 1, 120kDa
PCSK7 proprotein convertase subtilisin/kexin type 7
PCYOX1 prenylcysteine oxidase 1
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PELI1 pellino E3 ubiquitin protein ligase 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLA2G15 phospholipase A2, group XV
PLD3 phospholipase D family, member 3
PLS1 plastin 1
POLB polymerase (DNA directed), beta
POR P450 (cytochrome) oxidoreductase
PPARD peroxisome proliferator-activated receptor delta
PRDM14 PR domain containing 14
RAB33B RAB33B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RANBP10 RAN binding protein 10
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS2 regulator of G-protein signaling 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SEZ6L seizure related 6 homolog (mouse)-like
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPATA2 spermatogenesis associated 2
STK3 serine/threonine kinase 3
STX1A syntaxin 1A (brain)
STXBP1 syntaxin binding protein 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SYNJ1 synaptojanin 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM127 transmembrane protein 127
TMEM184B transmembrane protein 184B
TRADD TNFRSF1A-associated via death domain
TRIM62 tripartite motif containing 62
TSPAN13 tetraspanin 13
TSPYL2 TSPY-like 2
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
UBE4B ubiquitination factor E4B
WIPI1 WD repeat domain, phosphoinositide interacting 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC2HC1A zinc finger, C2HC-type containing 1A

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ANKRD55 ankyrin repeat domain 55
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBR apolipoprotein B receptor
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAHCC1 BAH domain and coiled-coil containing 1
C19ORF24 chromosome 19 open reading frame 24
C7ORF43 chromosome 7 open reading frame 43
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CAMKV CaM kinase-like vesicle-associated
CARTPT CART prepropeptide
CASD1 CAS1 domain containing 1
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CD180 CD180 molecule
CD33 CD33 molecule
CENPM centromere protein M
CFAP70 cilia and flagella associated protein 70
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLDN15 claudin 15
CLEC5A C-type lectin domain family 5, member A
CTCF CCCTC-binding factor (zinc finger protein)
CTSE cathepsin E
CXCL8 chemokine (C-X-C motif) ligand 8
CXORF21 chromosome X open reading frame 21
ELP3 elongator acetyltransferase complex subunit 3
EMILIN2 elastin microfibril interfacer 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FES FES proto-oncogene, tyrosine kinase
FGL2 fibrinogen-like 2
FMNL1 formin-like 1
GAB2 GRB2-associated binding protein 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GFI1 growth factor independent 1 transcription repressor
GMIP GEM interacting protein
GPR183 G protein-coupled receptor 183
GRWD1 glutamate-rich WD repeat containing 1
HOXC6 homeobox C6
HYI hydroxypyruvate isomerase (putative)
IFI35 interferon-induced protein 35
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMP5 lysosomal-associated membrane protein family, member 5
LIMD2 LIM domain containing 2
LMNB1 lamin B1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGOHB mago-nashi homolog B (Drosophila)
MAN2A2 mannosidase, alpha, class 2A, member 2
MILR1 mast cell immunoglobulin-like receptor 1
MNDA myeloid cell nuclear differentiation antigen
MON1B MON1 secretory trafficking family member B
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MXRA5 matrix-remodelling associated 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFE2 nuclear factor, erythroid 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NMI N-myc (and STAT) interactor
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
NXN nucleoredoxin
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PEF1 penta-EF-hand domain containing 1
PLEK2 pleckstrin 2
PPCS phosphopantothenoylcysteine synthetase
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRT protein tyrosine phosphatase, receptor type, T
RABL3 RAB, member of RAS oncogene family-like 3
RASL12 RAS-like, family 12
RNASE6 ribonuclease, RNase A family, k6
RNF44 ring finger protein 44
SAG S-antigen; retina and pineal gland (arrestin)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH3BP1 SH3-domain binding protein 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SNX17 sorting nexin 17
SPI1 Spi-1 proto-oncogene
SPRY2 sprouty homolog 2 (Drosophila)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
T T, brachyury homolog (mouse)
TARP TCR gamma alternate reading frame protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM185B transmembrane protein 185B
TOE1 target of EGR1, member 1 (nuclear)
TRIM8 tripartite motif containing 8
TTC27 tetratricopeptide repeat domain 27
UBIAD1 UbiA prenyltransferase domain containing 1
UBTF upstream binding transcription factor, RNA polymerase I
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WBSCR16 Williams-Beuren syndrome chromosome region 16
ZC3H4 zinc finger CCCH-type containing 4
ZEB2 zinc finger E-box binding homeobox 2
ZFR2 zinc finger RNA binding protein 2