valproic acid-433 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


197 genes differentially expressed following the valproic acid-433 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACAN aggrecan
ANAPC2 anaphase promoting complex subunit 2
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARSA arylsulfatase A
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BMP7 bone morphogenetic protein 7
BTG3 BTG family, member 3
C2CD2L C2CD2-like
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALD1 caldesmon 1
CCP110 centriolar coiled coil protein 110kDa
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHN2 chimerin 2
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CNR1 cannabinoid receptor 1 (brain)
CSH2 chorionic somatomammotropin hormone 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMXL2 Dmx-like 2
DND1 DND microRNA-mediated repression inhibitor 1
DPYSL4 dihydropyrimidinase-like 4
EGR1 early growth response 1
ELOVL6 ELOVL fatty acid elongase 6
EPOR erythropoietin receptor
FAM69A family with sequence similarity 69, member A
FER fer (fps/fes related) tyrosine kinase
FHL3 four and a half LIM domains 3
GMPR guanosine monophosphate reductase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HHLA1 HERV-H LTR-associating 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMGN5 high mobility group nucleosome binding domain 5
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IL19 interleukin 19
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM7A lysine (K)-specific demethylase 7A
KIFC1 kinesin family member C1
KLK12 kallikrein-related peptidase 12
KLK7 kallikrein-related peptidase 7
KRT85 keratin 85, type II
LIM2 lens intrinsic membrane protein 2, 19kDa
LIMK2 LIM domain kinase 2
LINC00652 long intergenic non-protein coding RNA 652
LINC01558 long intergenic non-protein coding RNA 1558
LMF1 lipase maturation factor 1
LYPD3 LY6/PLAUR domain containing 3
LZTS1 leucine zipper, putative tumor suppressor 1
MAOA monoamine oxidase A
MIS12 MIS12 kinetochore complex component
MITF microphthalmia-associated transcription factor
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSRB1 methionine sulfoxide reductase B1
MTSS1 metastasis suppressor 1
MYO9A myosin IXA
NDRG2 NDRG family member 2
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
PAQR3 progestin and adipoQ receptor family member III
PCSK7 proprotein convertase subtilisin/kexin type 7
PHF21A PHD finger protein 21A
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLBD1 phospholipase B domain containing 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPAT phosphoribosyl pyrophosphate amidotransferase
PRB1 proline-rich protein BstNI subfamily 1
PRKCA protein kinase C, alpha
PRRC2B proline-rich coiled-coil 2B
PTPRA protein tyrosine phosphatase, receptor type, A
RAB29 RAB29, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RNF24 ring finger protein 24
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFTPC surfactant protein C
SH2B2 SH2B adaptor protein 2
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SPDEF SAM pointed domain containing ETS transcription factor
SPG20 spastic paraplegia 20 (Troyer syndrome)
SSTR4 somatostatin receptor 4
STC1 stanniocalcin 1
STX7 syntaxin 7
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TMEM80 transmembrane protein 80
TNIK TRAF2 and NCK interacting kinase
TPST2 tyrosylprotein sulfotransferase 2
TSC22D4 TSC22 domain family, member 4
TTR transthyretin
UBE4B ubiquitination factor E4B
VENTX VENT homeobox
YIPF1 Yip1 domain family, member 1

decreased expression

Symbol Name
ANKRD36B ankyrin repeat domain 36B
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AVPR1B arginine vasopressin receptor 1B
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BTBD2 BTB (POZ) domain containing 2
C2CD5 C2 calcium-dependent domain containing 5
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CCNL2 cyclin L2
COMMD8 COMM domain containing 8
CUEDC1 CUE domain containing 1
DCPS decapping enzyme, scavenger
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ENO3 enolase 3 (beta, muscle)
EPX eosinophil peroxidase
EVPL envoplakin
FAM118A family with sequence similarity 118, member A
FASTKD3 FAST kinase domains 3
FKBP6 FK506 binding protein 6, 36kDa
FZD8 frizzled class receptor 8
GBX2 gastrulation brain homeobox 2
GLMN glomulin, FKBP associated protein
HAS2 hyaluronan synthase 2
HCG9 HLA complex group 9 (non-protein coding)
IL36RN interleukin 36 receptor antagonist
IL4R interleukin 4 receptor
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JAM3 junctional adhesion molecule 3
KEAP1 kelch-like ECH-associated protein 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYRM2 LYR motif containing 2
MEGF6 multiple EGF-like-domains 6
MEPCE methylphosphate capping enzyme
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MRPL12 mitochondrial ribosomal protein L12
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NMI N-myc (and STAT) interactor
NPTX1 neuronal pentraxin I
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OLFML1 olfactomedin-like 1
OR10H3 olfactory receptor, family 10, subfamily H, member 3
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI1 peptidyl arginine deiminase, type I
PCNP PEST proteolytic signal containing nuclear protein
PFAS phosphoribosylformylglycinamidine synthase
PISD phosphatidylserine decarboxylase
PNMA3 paraneoplastic Ma antigen 3
PRKCE protein kinase C, epsilon
PTOV1 prostate tumor overexpressed 1
PTX3 pentraxin 3, long
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RFWD3 ring finger and WD repeat domain 3
RIN2 Ras and Rab interactor 2
SALL2 spalt-like transcription factor 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPAG4 sperm associated antigen 4
STAB2 stabilin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TACC3 transforming, acidic coiled-coil containing protein 3
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TBX3 T-box 3
THSD4 thrombospondin, type I, domain containing 4
TKFC triokinase/FMN cyclase
TLN1 talin 1
TLR5 toll-like receptor 5
TMEM168 transmembrane protein 168
TMEM180 transmembrane protein 180
TMEM185B transmembrane protein 185B
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNS4 tensin 4
TOE1 target of EGR1, member 1 (nuclear)
UBQLN4 ubiquilin 4
VEGFC vascular endothelial growth factor C
WDR13 WD repeat domain 13
ZC3H7A zinc finger CCCH-type containing 7A
ZFR2 zinc finger RNA binding protein 2
ZNF302 zinc finger protein 302
ZNF358 zinc finger protein 358
ZNF580 zinc finger protein 580