valproic acid-4438 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the valproic acid-4438 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTN2 actinin, alpha 2
AKAP5 A kinase (PRKA) anchor protein 5
AMH anti-Mullerian hormone
ARHGAP28 Rho GTPase activating protein 28
ARRB1 arrestin, beta 1
ARSA arylsulfatase A
ARTN artemin
ATP10B ATPase, class V, type 10B
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCR8 chemokine (C-C motif) receptor 8
CD34 CD34 molecule
CD47 CD47 molecule
CDK20 cyclin-dependent kinase 20
CHL1 cell adhesion molecule L1-like
CLTA clathrin, light chain A
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPZ carboxypeptidase Z
CRYM crystallin, mu
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR2 DiGeorge syndrome critical region gene 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNA dystrobrevin, alpha
ECE1 endothelin converting enzyme 1
EDRF1 erythroid differentiation regulatory factor 1
EGR2 early growth response 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EML3 echinoderm microtubule associated protein like 3
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPS8L3 EPS8-like 3
FADS3 fatty acid desaturase 3
FAM134B family with sequence similarity 134, member B
FAS Fas cell surface death receptor
FGF1 fibroblast growth factor 1 (acidic)
FKBP10 FK506 binding protein 10, 65 kDa
FRMD4A FERM domain containing 4A
FUBP1 far upstream element (FUSE) binding protein 1
GGT1 gamma-glutamyltransferase 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HEMK1 HemK methyltransferase family member 1
HIST1H4B histone cluster 1, H4b
HPX hemopexin
IRF8 interferon regulatory factor 8
ITGA7 integrin, alpha 7
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JUND jun D proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF5C kinesin family member 5C
KLHL23 kelch-like family member 23
LGALS8 lectin, galactoside-binding, soluble, 8
LIMS2 LIM and senescent cell antigen-like domains 2
LRRC2 leucine rich repeat containing 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MIP major intrinsic protein of lens fiber
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MUC6 mucin 6, oligomeric mucus/gel-forming
NEU3 sialidase 3 (membrane sialidase)
NRF1 nuclear respiratory factor 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAG1 pleiomorphic adenoma gene 1
PRR5L proline rich 5 like
PSG9 pregnancy specific beta-1-glycoprotein 9
PTCH2 patched 2
QPRT quinolinate phosphoribosyltransferase
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBM34 RNA binding motif protein 34
RLN1 relaxin 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRPA signal-regulatory protein alpha
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYT1 synaptotagmin I
TGFB2 transforming growth factor, beta 2
TLL1 tolloid-like 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP53I11 tumor protein p53 inducible protein 11
TPP1 tripeptidyl peptidase I
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM48 tripartite motif containing 48
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
USP46 ubiquitin specific peptidase 46
UST uronyl-2-sulfotransferase
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
ZFP2 ZFP2 zinc finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZIM2 zinc finger, imprinted 2
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM23 ADAM metallopeptidase domain 23
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGAP10 Rho GTPase activating protein 10
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AURKC aurora kinase C
B9D2 B9 protein domain 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD79B CD79b molecule, immunoglobulin-associated beta
CENPO centromere protein O
CGREF1 cell growth regulator with EF-hand domain 1
CNGB3 cyclic nucleotide gated channel beta 3
DDN dendrin
DEPDC5 DEP domain containing 5
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPF3 D4, zinc and double PHD fingers, family 3
ENO3 enolase 3 (beta, muscle)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO31 F-box protein 31
FLCN folliculin
FMOD fibromodulin
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAN gigaxonin
GEMIN8 gem (nuclear organelle) associated protein 8
GJA9 gap junction protein, alpha 9, 59kDa
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GOLGA6A golgin A6 family, member A
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2BN histone cluster 1, H2bn
HIST1H3C histone cluster 1, H3c
HIST1H4C histone cluster 1, H4c
HLA-DMB major histocompatibility complex, class II, DM beta
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IL11RA interleukin 11 receptor, alpha
INO80D INO80 complex subunit D
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIRREL kin of IRRE like (Drosophila)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL21 kelch-like family member 21
LIN7B lin-7 homolog B (C. elegans)
MEFV Mediterranean fever
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MILR1 mast cell immunoglobulin-like receptor 1
MRAS muscle RAS oncogene homolog
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
NEUROD4 neuronal differentiation 4
NSUN6 NOP2/Sun domain family, member 6
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
POLL polymerase (DNA directed), lambda
POU3F2 POU class 3 homeobox 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTPRE protein tyrosine phosphatase, receptor type, E
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
SCG2 secretogranin II
SCIN scinderin
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMR3A submaxillary gland androgen regulated protein 3A
STAG3 stromal antigen 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
THRAP3 thyroid hormone receptor associated protein 3
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM45 tripartite motif containing 45
TSKU tsukushi, small leucine rich proteoglycan
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR25 WD repeat domain 25
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB33 zinc finger and BTB domain containing 33
ZNF280D zinc finger protein 280D
ZNF391 zinc finger protein 391
ZNF528 zinc finger protein 528
ZNF639 zinc finger protein 639
ZNF8 zinc finger protein 8
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN2 zinc finger and SCAN domain containing 2