valproic acid-497 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the valproic acid-497 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADGRA2 adhesion G protein-coupled receptor A2
ANG angiogenin, ribonuclease, RNase A family, 5
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATXN8OS ATXN8 opposite strand (non-protein coding)
BACE1 beta-site APP-cleaving enzyme 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BICD1 bicaudal D homolog 1 (Drosophila)
C10ORF76 chromosome 10 open reading frame 76
C19ORF66 chromosome 19 open reading frame 66
C2CD2L C2CD2-like
CD44 CD44 molecule (Indian blood group)
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDKN2A cyclin-dependent kinase inhibitor 2A
CER1 cerberus 1, DAN family BMP antagonist
CORO1A coronin, actin binding protein, 1A
CORO2A coronin, actin binding protein, 2A
CRY1 cryptochrome circadian clock 1
CTTN cortactin
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPEP1 dipeptidase 1 (renal)
DST dystonin
EFNA3 ephrin-A3
ENO2 enolase 2 (gamma, neuronal)
EPHB1 EPH receptor B1
FAM162A family with sequence similarity 162, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLRX glutaredoxin (thioltransferase)
GMIP GEM interacting protein
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GSDMB gasdermin B
GSK3A glycogen synthase kinase 3 alpha
GYPB glycophorin B (MNS blood group)
HSPA12A heat shock 70kDa protein 12A
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL4R interleukin 4 receptor
ITGA6 integrin, alpha 6
KIF5C kinesin family member 5C
KLK8 kallikrein-related peptidase 8
KREMEN2 kringle containing transmembrane protein 2
LGMN legumain
LIN7B lin-7 homolog B (C. elegans)
MAGEH1 melanoma antigen family H1
MAPT microtubule-associated protein tau
MOGAT2 monoacylglycerol O-acyltransferase 2
MTO1 mitochondrial tRNA translation optimization 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOTCH3 notch 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
ORAI2 ORAI calcium release-activated calcium modulator 2
PADI1 peptidyl arginine deiminase, type I
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDLIM7 PDZ and LIM domain 7 (enigma)
PHF21A PHD finger protein 21A
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRDM14 PR domain containing 14
RAB29 RAB29, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
REEP1 receptor accessory protein 1
RGS3 regulator of G-protein signaling 3
RITA1 RBPJ interacting and tubulin associated 1
RND2 Rho family GTPase 2
RNF185 ring finger protein 185
RORC RAR-related orphan receptor C
RRAGD Ras-related GTP binding D
RRBP1 ribosome binding protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SFXN3 sideroflexin 3
SGCE sarcoglycan, epsilon
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMCO4 single-pass membrane protein with coiled-coil domains 4
SSUH2 ssu-2 homolog (C. elegans)
STARD5 StAR-related lipid transfer (START) domain containing 5
STK19 serine/threonine kinase 19
STX2 syntaxin 2
SUSD4 sushi domain containing 4
TM7SF3 transmembrane 7 superfamily member 3
TSPYL2 TSPY-like 2
TTC28 tetratricopeptide repeat domain 28
ULBP2 UL16 binding protein 2
WDR48 WD repeat domain 48
WSCD1 WSC domain containing 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACAD10 acyl-CoA dehydrogenase family, member 10
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APITD1 apoptosis-inducing, TAF9-like domain 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AVEN apoptosis, caspase activation inhibitor
AXIN1 axin 1
BANP BTG3 associated nuclear protein
C21ORF62 chromosome 21 open reading frame 62
C7ORF43 chromosome 7 open reading frame 43
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CD320 CD320 molecule
CD5 CD5 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDCA8 cell division cycle associated 8
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CETN1 centrin, EF-hand protein, 1
CFAP69 cilia and flagella associated protein 69
CHKB choline kinase beta
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTD2 cyclin N-terminal domain containing 2
DCPS decapping enzyme, scavenger
DGAT1 diacylglycerol O-acyltransferase 1
DRP2 dystrophin related protein 2
EFCAB1 EF-hand calcium binding domain 1
ERCC2 excision repair cross-complementation group 2
EVPL envoplakin
EXOC6B exocyst complex component 6B
EXOSC9 exosome component 9
FAM153A family with sequence similarity 153, member A
FANCF Fanconi anemia, complementation group F
FGF13 fibroblast growth factor 13
FTCD formimidoyltransferase cyclodeaminase
GAL3ST4 galactose-3-O-sulfotransferase 4
GALR3 galanin receptor 3
GPR87 G protein-coupled receptor 87
GREB1L growth regulation by estrogen in breast cancer-like
GTPBP6 GTP binding protein 6 (putative)
HMX1 H6 family homeobox 1
HOXC4 homeobox C4
JOSD1 Josephin domain containing 1
KEAP1 kelch-like ECH-associated protein 1
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLK7 kallikrein-related peptidase 7
KRT8P12 keratin 8 pseudogene 12
LINC00574 long intergenic non-protein coding RNA 574
LOC100286895 cell division cycle 27 homolog pseudogene
MALL mal, T-cell differentiation protein-like
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MPDU1 mannose-P-dolichol utilization defect 1
MTERF3 mitochondrial transcription termination factor 3
MYO19 myosin XIX
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
ONECUT2 one cut homeobox 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHOX2A paired-like homeobox 2a
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PNMA3 paraneoplastic Ma antigen 3
PNRC1 proline-rich nuclear receptor coactivator 1
PON3 paraoxonase 3
PPCS phosphopantothenoylcysteine synthetase
PRSS23 protease, serine, 23
PSCA prostate stem cell antigen
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRT protein tyrosine phosphatase, receptor type, T
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAD54L RAD54-like (S. cerevisiae)
RNF220 ring finger protein 220
SECISBP2 SECIS binding protein 2
SLC35A5 solute carrier family 35, member A5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX21 SRY (sex determining region Y)-box 21
STRA13 stimulated by retinoic acid 13
SYNPO synaptopodin
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TET3 tet methylcytosine dioxygenase 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR5 toll-like receptor 5
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM168 transmembrane protein 168
TMEM39B transmembrane protein 39B
TNS4 tensin 4
TRAC T cell receptor alpha constant
TRAPPC12 trafficking protein particle complex 12
TREML2 triggering receptor expressed on myeloid cells-like 2
TSHZ2 teashirt zinc finger homeobox 2
ZNF180 zinc finger protein 180