valproic acid-5206 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the valproic acid-5206 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAM22 ADAM metallopeptidase domain 22
ADAP2 ArfGAP with dual PH domains 2
APC adenomatous polyposis coli
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPH aspartate beta-hydroxylase
BEX4 brain expressed, X-linked 4
BMP7 bone morphogenetic protein 7
BTN2A2 butyrophilin, subfamily 2, member A2
CCDC28B coiled-coil domain containing 28B
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CLGN calmegin
CNOT2 CCR4-NOT transcription complex, subunit 2
CSRP2 cysteine and glycine-rich protein 2
DBN1 drebrin 1
DIXDC1 DIX domain containing 1
DSE dermatan sulfate epimerase
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EHD2 EH-domain containing 2
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
ENO2 enolase 2 (gamma, neuronal)
EPHB2 EPH receptor B2
FAM105A family with sequence similarity 105, member A
FAM214B family with sequence similarity 214, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
FYN FYN proto-oncogene, Src family tyrosine kinase
GK3P glycerol kinase 3 pseudogene
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GPR137 G protein-coupled receptor 137
GRB10 growth factor receptor-bound protein 10
GRK5 G protein-coupled receptor kinase 5
GYG2 glycogenin 2
HAP1 huntingtin-associated protein 1
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMGN5 high mobility group nucleosome binding domain 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA1109 KIAA1109
KLHL23 kelch-like family member 23
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LHX2 LIM homeobox 2
LMO4 LIM domain only 4
LRRC14 leucine rich repeat containing 14
MARK4 MAP/microtubule affinity-regulating kinase 4
METTL7A methyltransferase like 7A
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTCP1 mature T-cell proliferation 1
MTSS1 metastasis suppressor 1
NME5 NME/NM23 family member 5
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
PDE9A phosphodiesterase 9A
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PGAP1 post-GPI attachment to proteins 1
PROS1 protein S (alpha)
PTCH1 patched 1
RAB29 RAB29, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD51B RAD51 paralog B
RALGDS ral guanine nucleotide dissociation stimulator
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RB1CC1 RB1-inducible coiled-coil 1
REEP2 receptor accessory protein 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RLN1 relaxin 1
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFXN3 sideroflexin 3
SRPX sushi-repeat containing protein, X-linked
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYNGR3 synaptogyrin 3
TBC1D19 TBC1 domain family, member 19
TESC tescalcin
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNIK TRAF2 and NCK interacting kinase
TTC33 tetratricopeptide repeat domain 33
TTC9 tetratricopeptide repeat domain 9
ULBP2 UL16 binding protein 2
ULK2 unc-51 like autophagy activating kinase 2
VLDLR very low density lipoprotein receptor
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF204P zinc finger protein 204, pseudogene
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ALS2CL ALS2 C-terminal like
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARPIN actin-related protein 2/3 complex inhibitor
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C10ORF95 chromosome 10 open reading frame 95
C14ORF93 chromosome 14 open reading frame 93
C19ORF40 chromosome 19 open reading frame 40
C1ORF105 chromosome 1 open reading frame 105
C9ORF91 chromosome 9 open reading frame 91
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CGA glycoprotein hormones, alpha polypeptide
CISH cytokine inducible SH2-containing protein
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
ESRP2 epithelial splicing regulatory protein 2
EXD3 exonuclease 3'-5' domain containing 3
FAAH fatty acid amide hydrolase
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AI histone cluster 1, H2ai
HIST1H2AL histone cluster 1, H2al
HIST1H2BJ histone cluster 1, H2bj
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INCENP inner centromere protein antigens 135/155kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM8 lysine (K)-specific demethylase 8
KIFC1 kinesin family member C1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LY6D lymphocyte antigen 6 complex, locus D
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED18 mediator complex subunit 18
MMP3 matrix metallopeptidase 3
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYO1F myosin IF
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NARFL nuclear prelamin A recognition factor-like
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PRODH proline dehydrogenase (oxidase) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
QSER1 glutamine and serine rich 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFTN1 raftlin, lipid raft linker 1
RNF43 ring finger protein 43
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEPP1 selenoprotein P, plasma, 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMR3A submaxillary gland androgen regulated protein 3A
STARD13 StAR-related lipid transfer (START) domain containing 13
STK16 serine/threonine kinase 16
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEP1 telomerase-associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM212 transmembrane protein 212
TMPRSS3 transmembrane protease, serine 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC17 tetratricopeptide repeat domain 17
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
WDR76 WD repeat domain 76
WWC3 WWC family member 3
ZBTB44 zinc finger and BTB domain containing 44
ZNF428 zinc finger protein 428
ZNF669 zinc finger protein 669
ZNF76 zinc finger protein 76
ZNF816 zinc finger protein 816
ZNHIT2 zinc finger, HIT-type containing 2