Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the valproic acid-5574 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AASS | aminoadipate-semialdehyde synthase |
ACACB | acetyl-CoA carboxylase beta |
ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
ALDOB | aldolase B, fructose-bisphosphate |
AQP4 | aquaporin 4 |
ATAT1 | alpha tubulin acetyltransferase 1 |
BGN | biglycan |
C14ORF105 | chromosome 14 open reading frame 105 |
CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
CD248 | CD248 molecule, endosialin |
CD48 | CD48 molecule |
CD79A | CD79a molecule, immunoglobulin-associated alpha |
CDHR2 | cadherin-related family member 2 |
CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
CLDN17 | claudin 17 |
CLIC2 | chloride intracellular channel 2 |
CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
CTNS | cystinosin, lysosomal cystine transporter |
CYHR1 | cysteine/histidine-rich 1 |
CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
DCHS2 | dachsous cadherin-related 2 |
DFNB31 | deafness, autosomal recessive 31 |
DLL3 | delta-like 3 (Drosophila) |
DLX2 | distal-less homeobox 2 |
DNAH7 | dynein, axonemal, heavy chain 7 |
DPF1 | D4, zinc and double PHD fingers family 1 |
DRD2 | dopamine receptor D2 |
DTX3 | deltex 3, E3 ubiquitin ligase |
DZIP1 | DAZ interacting zinc finger protein 1 |
ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
FADS3 | fatty acid desaturase 3 |
FAXDC2 | fatty acid hydroxylase domain containing 2 |
FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
FGFR1OP | FGFR1 oncogene partner |
FRMPD1 | FERM and PDZ domain containing 1 |
FSCN1 | fascin actin-bundling protein 1 |
FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
GGT1 | gamma-glutamyltransferase 1 |
GJA9 | gap junction protein, alpha 9, 59kDa |
GP2 | glycoprotein 2 (zymogen granule membrane) |
HAB1 | B1 for mucin |
HFE | hemochromatosis |
HP | haptoglobin |
INHA | inhibin, alpha |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
IRS4 | insulin receptor substrate 4 |
KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
KCTD17 | potassium channel tetramerization domain containing 17 |
KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
LAMA4 | laminin, alpha 4 |
LAT2 | linker for activation of T cells family, member 2 |
LEFTY2 | left-right determination factor 2 |
LHX1 | LIM homeobox 1 |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
LRP12 | low density lipoprotein receptor-related protein 12 |
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
MMP11 | matrix metallopeptidase 11 |
MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
MMP25 | matrix metallopeptidase 25 |
MUC6 | mucin 6, oligomeric mucus/gel-forming |
MVB12B | multivesicular body subunit 12B |
NELL2 | NEL-like 2 (chicken) |
NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
NRG1 | neuregulin 1 |
NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
NUDCD3 | NudC domain containing 3 |
PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
PDGFD | platelet derived growth factor D |
PEG3 | paternally expressed 3 |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PQLC3 | PQ loop repeat containing 3 |
PTGIS | prostaglandin I2 (prostacyclin) synthase |
RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
RGS10 | regulator of G-protein signaling 10 |
RIMS2 | regulating synaptic membrane exocytosis 2 |
RLN1 | relaxin 1 |
RUFY3 | RUN and FYVE domain containing 3 |
RUNX1 | runt-related transcription factor 1 |
SHANK1 | SH3 and multiple ankyrin repeat domains 1 |
SIT1 | signaling threshold regulating transmembrane adaptor 1 |
SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 |
SLURP1 | secreted LY6/PLAUR domain containing 1 |
SSX3 | synovial sarcoma, X breakpoint 3 |
SYNPO | synaptopodin |
TBXA2R | thromboxane A2 receptor |
TCF3 | transcription factor 3 |
TGFA | transforming growth factor, alpha |
THBS1 | thrombospondin 1 |
TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
TP63 | tumor protein p63 |
TUBA3C | tubulin, alpha 3c |
VGLL3 | vestigial-like family member 3 |
ZC3H7B | zinc finger CCCH-type containing 7B |
Symbol | Name |
---|---|
ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
APH1A | APH1A gamma secretase subunit |
APOLD1 | apolipoprotein L domain containing 1 |
ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
ATP11B | ATPase, class VI, type 11B |
C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
CA11 | carbonic anhydrase XI |
CA5BP1 | carbonic anhydrase VB pseudogene 1 |
CBX4 | chromobox homolog 4 |
CCDC69 | coiled-coil domain containing 69 |
CCNO | cyclin O |
CHKB | choline kinase beta |
CLDN15 | claudin 15 |
CLSPN | claspin |
CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
CRLF1 | cytokine receptor-like factor 1 |
CST6 | cystatin E/M |
CSTA | cystatin A (stefin A) |
CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
DCAF17 | DDB1 and CUL4 associated factor 17 |
DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
ERCC6 | excision repair cross-complementation group 6 |
ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FBXO46 | F-box protein 46 |
FBXO5 | F-box protein 5 |
FOXC1 | forkhead box C1 |
GSTCD | glutathione S-transferase, C-terminal domain containing |
HCFC1 | host cell factor C1 |
HOXA4 | homeobox A4 |
KAT2A | K(lysine) acetyltransferase 2A |
KLF2 | Kruppel-like factor 2 |
KPNA4 | karyopherin alpha 4 (importin alpha 3) |
L2HGDH | L-2-hydroxyglutarate dehydrogenase |
LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
LOC100286895 | cell division cycle 27 homolog pseudogene |
LUC7L | LUC7-like (S. cerevisiae) |
MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
NEK11 | NIMA-related kinase 11 |
NT5DC3 | 5'-nucleotidase domain containing 3 |
NT5E | 5'-nucleotidase, ecto (CD73) |
OPN3 | opsin 3 |
P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
PGP | phosphoglycolate phosphatase |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
POLL | polymerase (DNA directed), lambda |
PROS1 | protein S (alpha) |
PTDSS2 | phosphatidylserine synthase 2 |
PTPRS | protein tyrosine phosphatase, receptor type, S |
PYCRL | pyrroline-5-carboxylate reductase-like |
RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RRAGB | Ras-related GTP binding B |
RSF1 | remodeling and spacing factor 1 |
SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
SDC3 | syndecan 3 |
SGCE | sarcoglycan, epsilon |
SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
SGMS1 | sphingomyelin synthase 1 |
SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
SLMO1 | slowmo homolog 1 (Drosophila) |
SREBF1 | sterol regulatory element binding transcription factor 1 |
TBX19 | T-box 19 |
TCTN1 | tectonic family member 1 |
TESK1 | testis-specific kinase 1 |
TICAM1 | toll-like receptor adaptor molecule 1 |
TLR5 | toll-like receptor 5 |
TM6SF1 | transmembrane 6 superfamily member 1 |
TMEM104 | transmembrane protein 104 |
TMEM120B | transmembrane protein 120B |
TMEM2 | transmembrane protein 2 |
TMEM53 | transmembrane protein 53 |
TMEM62 | transmembrane protein 62 |
TPTE | transmembrane phosphatase with tensin homology |
TRDMT1 | tRNA aspartic acid methyltransferase 1 |
TRIM25 | tripartite motif containing 25 |
TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
UNKL | unkempt family zinc finger-like |
VPS9D1 | VPS9 domain containing 1 |
WDR43 | WD repeat domain 43 |
ZBTB44 | zinc finger and BTB domain containing 44 |
ZC3H3 | zinc finger CCCH-type containing 3 |
ZIC1 | Zic family member 1 |
ZNF134 | zinc finger protein 134 |
ZNF141 | zinc finger protein 141 |
ZNF442 | zinc finger protein 442 |
ZNF532 | zinc finger protein 532 |
ZNF747 | zinc finger protein 747 |