valproic acid-6929 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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193 genes differentially expressed following the valproic acid-6929 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ASIC1 acid sensing (proton gated) ion channel 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BLVRA biliverdin reductase A
C2ORF54 chromosome 2 open reading frame 54
CCNT1 cyclin T1
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDON cell adhesion associated, oncogene regulated
CLCF1 cardiotrophin-like cytokine factor 1
CLCN7 chloride channel, voltage-sensitive 7
CLTC clathrin, heavy chain (Hc)
CRLF1 cytokine receptor-like factor 1
CRYBG3 beta-gamma crystallin domain containing 3
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAPK2 death-associated protein kinase 2
DSCAM Down syndrome cell adhesion molecule
EDA ectodysplasin A
EMID1 EMI domain containing 1
EXOSC2 exosome component 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM114A2 family with sequence similarity 114, member A2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FYN FYN proto-oncogene, Src family tyrosine kinase
GALK2 galactokinase 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HFE hemochromatosis
HIST1H2BJ histone cluster 1, H2bj
HRK harakiri, BCL2 interacting protein
HSDL2 hydroxysteroid dehydrogenase like 2
IFI6 interferon, alpha-inducible protein 6
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM4C lysine (K)-specific demethylase 4C
KIAA0319L KIAA0319-like
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT15 keratin 15, type I
LAMC2 laminin, gamma 2
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN1C1 mannosidase, alpha, class 1C, member 1
METTL21B methyltransferase like 21B
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NAV2 neuron navigator 2
NF2 neurofibromin 2 (merlin)
NFIB nuclear factor I/B
NPTX1 neuronal pentraxin I
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PILRA paired immunoglobin-like type 2 receptor alpha
PLAA phospholipase A2-activating protein
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QKI QKI, KH domain containing, RNA binding
RFTN1 raftlin, lipid raft linker 1
RGS12 regulator of G-protein signaling 12
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAB1 stabilin 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBC1D30 TBC1 domain family, member 30
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TRAK1 trafficking protein, kinesin binding 1
TRIM14 tripartite motif containing 14
TSPAN9 tetraspanin 9
TUBA3C tubulin, alpha 3c
UEVLD UEV and lactate/malate dehyrogenase domains
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAV2 vav 2 guanine nucleotide exchange factor
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
WNT10B wingless-type MMTV integration site family, member 10B
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF428 zinc finger protein 428
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ASB9 ankyrin repeat and SOCS box containing 9
ATP11B ATPase, class VI, type 11B
AUH AU RNA binding protein/enoyl-CoA hydratase
BEX4 brain expressed, X-linked 4
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
BRIX1 BRX1, biogenesis of ribosomes
C1ORF115 chromosome 1 open reading frame 115
C3ORF52 chromosome 3 open reading frame 52
C5 complement component 5
CBX4 chromobox homolog 4
CCNL2 cyclin L2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPJ centromere protein J
CERK ceramide kinase
COCH cochlin
COG4 component of oligomeric golgi complex 4
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DCLRE1A DNA cross-link repair 1A
DCTN4 dynactin 4 (p62)
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAL4 dynein, axonemal, light chain 4
ECHDC2 enoyl CoA hydratase domain containing 2
EDC3 enhancer of mRNA decapping 3
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFCAB2 EF-hand calcium binding domain 2
FAM160B2 family with sequence similarity 160, member B2
FGD6 FYVE, RhoGEF and PH domain containing 6
FUZ fuzzy planar cell polarity protein
FXN frataxin
FZD4 frizzled class receptor 4
GMIP GEM interacting protein
GTPBP2 GTP binding protein 2
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
IFT22 intraflagellar transport 22
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INSIG2 insulin induced gene 2
KDM5C lysine (K)-specific demethylase 5C
KLHL26 kelch-like family member 26
KRBOX4 KRAB box domain containing 4
LARS leucyl-tRNA synthetase
LZTFL1 leucine zipper transcription factor-like 1
MANBA mannosidase, beta A, lysosomal
MED23 mediator complex subunit 23
MKS1 Meckel syndrome, type 1
MTRF1 mitochondrial translational release factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
MYLIP myosin regulatory light chain interacting protein
NCAM2 neural cell adhesion molecule 2
OCLN occludin
OGFRL1 opioid growth factor receptor-like 1
PACS1 phosphofurin acidic cluster sorting protein 1
PBLD phenazine biosynthesis-like protein domain containing
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PODXL2 podocalyxin-like 2
PROCR protein C receptor, endothelial
QTRT1 queuine tRNA-ribosyltransferase 1
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RNF220 ring finger protein 220
RNF31 ring finger protein 31
SAV1 salvador family WW domain containing protein 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SFXN1 sideroflexin 1
SIRT6 sirtuin 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPINK4 serine peptidase inhibitor, Kazal type 4
SSFA2 sperm specific antigen 2
SSNA1 Sjogren syndrome nuclear autoantigen 1
TBC1D17 TBC1 domain family, member 17
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TESK1 testis-specific kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM115 transmembrane protein 115
TRAPPC2 trafficking protein particle complex 2
TRIM13 tripartite motif containing 13
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
XKR8 XK, Kell blood group complex subunit-related family, member 8
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFP30 ZFP30 zinc finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF248 zinc finger protein 248
ZNF273 zinc finger protein 273
ZNF552 zinc finger protein 552
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF816 zinc finger protein 816