valproic acid-6974 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the valproic acid-6974 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABHD17B abhydrolase domain containing 17B
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE5 adhesion G protein-coupled receptor E5
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANKRD12 ankyrin repeat domain 12
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACFD1 calcium channel flower domain containing 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCNO cyclin O
CD47 CD47 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPO centromere protein O
CLMN calmin (calponin-like, transmembrane)
CUL9 cullin 9
CYLD cylindromatosis (turban tumor syndrome)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYTH1 cytohesin 1
DESI2 desumoylating isopeptidase 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EIF5 eukaryotic translation initiation factor 5
FCHO1 FCH domain only 1
FGFR2 fibroblast growth factor receptor 2
GAMT guanidinoacetate N-methyltransferase
GFI1 growth factor independent 1 transcription repressor
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GRSF1 G-rich RNA sequence binding factor 1
GTDC1 glycosyltransferase-like domain containing 1
H2AFX H2A histone family, member X
HIST1H1E histone cluster 1, H1e
HIST1H3A histone cluster 1, H3a
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HSDL2 hydroxysteroid dehydrogenase like 2
IL4R interleukin 4 receptor
IPP intracisternal A particle-promoted polypeptide
JRK Jrk homolog (mouse)
KIF13B kinesin family member 13B
KIF5C kinesin family member 5C
KRT17 keratin 17, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMK2 LIM domain kinase 2
LMAN1 lectin, mannose-binding, 1
LMF1 lipase maturation factor 1
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MALT1 MALT1 paracaspase
MANBA mannosidase, beta A, lysosomal
MAPT microtubule-associated protein tau
MAST3 microtubule associated serine/threonine kinase 3
MID1 midline 1
MTMR2 myotubularin related protein 2
MVP major vault protein
NEBL nebulette
NKAIN1 Na+/K+ transporting ATPase interacting 1
NME5 NME/NM23 family member 5
NPFFR1 neuropeptide FF receptor 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OSMR oncostatin M receptor
PADI1 peptidyl arginine deiminase, type I
PAX5 paired box 5
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB3 protocadherin beta 3
PDE3B phosphodiesterase 3B, cGMP-inhibited
PNPLA6 patatin-like phospholipase domain containing 6
POLL polymerase (DNA directed), lambda
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB33A RAB33A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RNF39 ring finger protein 39
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RRAGB Ras-related GTP binding B
RRBP1 ribosome binding protein 1
SIKE1 suppressor of IKBKE 1
SKIL SKI-like proto-oncogene
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STK11 serine/threonine kinase 11
STX1A syntaxin 1A (brain)
TACC1 transforming, acidic coiled-coil containing protein 1
TADA3 transcriptional adaptor 3
TAT tyrosine aminotransferase
TBC1D22A TBC1 domain family, member 22A
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TLE4 transducin-like enhancer of split 4
TPM1 tropomyosin 1 (alpha)
TRAPPC10 trafficking protein particle complex 10
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WNT16 wingless-type MMTV integration site family, member 16
YLPM1 YLP motif containing 1
ZMYM6 zinc finger, MYM-type 6
ZNF16 zinc finger protein 16
ZNF345 zinc finger protein 345
ZNF419 zinc finger protein 419
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGAP11A Rho GTPase activating protein 11A
ARMC6 armadillo repeat containing 6
ATG14 autophagy related 14
ATG2A autophagy related 2A
AXIN1 axin 1
BAK1 BCL2-antagonist/killer 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBC3 BCL2 binding component 3
BCL2L2 BCL2-like 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF56 chromosome 1 open reading frame 56
C2ORF44 chromosome 2 open reading frame 44
CA11 carbonic anhydrase XI
CAPG capping protein (actin filament), gelsolin-like
CAPN15 calpain 15
CBX4 chromobox homolog 4
CCDC15 coiled-coil domain containing 15
CHMP7 charged multivesicular body protein 7
CLEC16A C-type lectin domain family 16, member A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DVL1 dishevelled segment polarity protein 1
EGLN1 egl-9 family hypoxia-inducible factor 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ESYT1 extended synaptotagmin-like protein 1
FAM188A family with sequence similarity 188, member A
FAM86B1 family with sequence similarity 86, member B1
FOSL1 FOS-like antigen 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP2 GTP binding protein 2
IMPACT impact RWD domain protein
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM5C lysine (K)-specific demethylase 5C
KLF3 Kruppel-like factor 3 (basic)
KRBOX4 KRAB box domain containing 4
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
MATK megakaryocyte-associated tyrosine kinase
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMP9 matrix metallopeptidase 9
MORC3 MORC family CW-type zinc finger 3
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFE2L3 nuclear factor, erythroid 2-like 3
PACS1 phosphofurin acidic cluster sorting protein 1
PADI2 peptidyl arginine deiminase, type II
PGP phosphoglycolate phosphatase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PKD2 polycystic kidney disease 2 (autosomal dominant)
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSKH1 protein serine kinase H1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF123 ring finger protein 123
SCAMP4 secretory carrier membrane protein 4
SCML2 sex comb on midleg-like 2 (Drosophila)
SH3GL1 SH3-domain GRB2-like 1
SLC25A40 solute carrier family 25, member 40
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX3 SRY (sex determining region Y)-box 3
SPRYD7 SPRY domain containing 7
SSFA2 sperm specific antigen 2
STBD1 starch binding domain 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUN2 Sad1 and UNC84 domain containing 2
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TCTN2 tectonic family member 2
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBGCP5 tubulin, gamma complex associated protein 5
UNKL unkempt family zinc finger-like
XAB2 XPA binding protein 2
XYLT2 xylosyltransferase II
ZC3H12A zinc finger CCCH-type containing 12A
ZNF280D zinc finger protein 280D
ZNF282 zinc finger protein 282
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF574 zinc finger protein 574
ZNF668 zinc finger protein 668
ZNF778 zinc finger protein 778
ZSCAN9 zinc finger and SCAN domain containing 9