valproic acid-6999 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the valproic acid-6999 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AFAP1 actin filament associated protein 1
AHI1 Abelson helper integration site 1
AK1 adenylate kinase 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARL4C ADP-ribosylation factor-like 4C
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTN2A2 butyrophilin, subfamily 2, member A2
C7ORF43 chromosome 7 open reading frame 43
CCPG1 cell cycle progression 1
CLMN calmin (calponin-like, transmembrane)
COL5A1 collagen, type V, alpha 1
CRY2 cryptochrome circadian clock 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EHBP1L1 EH domain binding protein 1-like 1
EHD2 EH-domain containing 2
EPOR erythropoietin receptor
ERO1L ERO1-like (S. cerevisiae)
F11R F11 receptor
FAM53B family with sequence similarity 53, member B
FBXO42 F-box protein 42
FHL1 four and a half LIM domains 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPC4 glypican 4
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HIST1H4A histone cluster 1, H4a
HLA-E major histocompatibility complex, class I, E
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IRF6 interferon regulatory factor 6
IRGQ immunity-related GTPase family, Q
ITGA6 integrin, alpha 6
JAG2 jagged 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM6A lysine (K)-specific demethylase 6A
KIAA1109 KIAA1109
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT83 keratin 83, type II
LAPTM5 lysosomal protein transmembrane 5
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LOC647070 uncharacterized LOC647070
LPPR2 lipid phosphate phosphatase-related protein type 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPT microtubule-associated protein tau
MBNL2 muscleblind-like splicing regulator 2
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MTCL1 microtubule crosslinking factor 1
MTMR6 myotubularin related protein 6
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MVP major vault protein
MZF1 myeloid zinc finger 1
NCOA1 nuclear receptor coactivator 1
NEBL nebulette
NF2 neurofibromin 2 (merlin)
PHKB phosphorylase kinase, beta
PLCH1 phospholipase C, eta 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMEL premelanosome protein
PNPLA6 patatin-like phospholipase domain containing 6
PRICKLE3 prickle homolog 3 (Drosophila)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRPH peripherin
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTCH1 patched 1
PVRL3 poliovirus receptor-related 3
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCAN3 RCAN family member 3
RPH3AL rabphilin 3A-like (without C2 domains)
RPLP2 ribosomal protein, large, P2
RRBP1 ribosome binding protein 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3BP2 SH3-domain binding protein 2
SIK1 salt-inducible kinase 1
SOGA1 suppressor of glucose, autophagy associated 1
STXBP1 syntaxin binding protein 1
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
THBD thrombomodulin
TIAM1 T-cell lymphoma invasion and metastasis 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPM1 tropomyosin 1 (alpha)
TRAIP TRAF interacting protein
TTC28 tetratricopeptide repeat domain 28
TTC9 tetratricopeptide repeat domain 9
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZBTB40 zinc finger and BTB domain containing 40
ZFAND6 zinc finger, AN1-type domain 6
ZNF16 zinc finger protein 16
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACTL8 actin-like 8
ADAP2 ArfGAP with dual PH domains 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD2B ATPase family, AAA domain containing 2B
C10ORF95 chromosome 10 open reading frame 95
C17ORF80 chromosome 17 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C1ORF123 chromosome 1 open reading frame 123
C21ORF91 chromosome 21 open reading frame 91
C2ORF44 chromosome 2 open reading frame 44
CDK3 cyclin-dependent kinase 3
CENPO centromere protein O
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CLCN5 chloride channel, voltage-sensitive 5
CNGB3 cyclic nucleotide gated channel beta 3
CSF1R colony stimulating factor 1 receptor
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTAGE9 CTAGE family, member 9
CXORF56 chromosome X open reading frame 56
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DOCK1 dedicator of cytokinesis 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPHA2 EPH receptor A2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAAH fatty acid amide hydrolase
FAM188A family with sequence similarity 188, member A
FAM86C1 family with sequence similarity 86, member C1
FKBP10 FK506 binding protein 10, 65 kDa
FURIN furin (paired basic amino acid cleaving enzyme)
GAN gigaxonin
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR27 G protein-coupled receptor 27
GRWD1 glutamate-rich WD repeat containing 1
GSTT1 glutathione S-transferase theta 1
HIST1H2BC histone cluster 1, H2bc
HLA-DMA major histocompatibility complex, class II, DM alpha
JMJD4 jumonji domain containing 4
KREMEN2 kringle containing transmembrane protein 2
LAMA3 laminin, alpha 3
LMCD1 LIM and cysteine-rich domains 1
LRP5L low density lipoprotein receptor-related protein 5-like
LY6D lymphocyte antigen 6 complex, locus D
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MTA2 metastasis associated 1 family, member 2
MYL5 myosin, light chain 5, regulatory
NAP1L2 nucleosome assembly protein 1-like 2
NHEJ1 nonhomologous end-joining factor 1
NSUN3 NOP2/Sun domain family, member 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLD3 phospholipase D family, member 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
RAB27B RAB27B, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RECQL4 RecQ protein-like 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS17 regulator of G-protein signaling 17
RIC8B RIC8 guanine nucleotide exchange factor B
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH2D4A SH2 domain containing 4A
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SYCP2 synaptonemal complex protein 2
TCTN2 tectonic family member 2
TEP1 telomerase-associated protein 1
THOP1 thimet oligopeptidase 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM183A transmembrane protein 183A
TMPRSS3 transmembrane protease, serine 3
TUBGCP5 tubulin, gamma complex associated protein 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
WWC3 WWC family member 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED8 zinc finger, BED-type containing 8
ZBTB38 zinc finger and BTB domain containing 38
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZSCAN26 zinc finger and SCAN domain containing 26