valproic acid-989 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the valproic acid-989 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVR1B activin A receptor, type IB
ADAM19 ADAM metallopeptidase domain 19
AGFG2 ArfGAP with FG repeats 2
AHNAK2 AHNAK nucleoprotein 2
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF7 activating transcription factor 7
BCORL1 BCL6 corepressor-like 1
BEX4 brain expressed, X-linked 4
BTN2A2 butyrophilin, subfamily 2, member A2
CA11 carbonic anhydrase XI
CBX7 chromobox homolog 7
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC28B coiled-coil domain containing 28B
CD83 CD83 molecule
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN5 chloride channel, voltage-sensitive 5
CRLF1 cytokine receptor-like factor 1
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTSV cathepsin V
CYHR1 cysteine/histidine-rich 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DBN1 drebrin 1
DFNB31 deafness, autosomal recessive 31
DIXDC1 DIX domain containing 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
ETV5 ets variant 5
FAM184A family with sequence similarity 184, member A
FBXL2 F-box and leucine-rich repeat protein 2
FHL1 four and a half LIM domains 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GJB3 gap junction protein, beta 3, 31kDa
GLRX glutaredoxin (thioltransferase)
GPR153 G protein-coupled receptor 153
GPRC5B G protein-coupled receptor, class C, group 5, member B
GYG2 glycogenin 2
HCRP1 hepatocellular carcinoma-related HCRP1
IL4R interleukin 4 receptor
JAG2 jagged 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0895 KIAA0895
KIF1A kinesin family member 1A
KIF5C kinesin family member 5C
LARP6 La ribonucleoprotein domain family, member 6
LDB1 LIM domain binding 1
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAPT microtubule-associated protein tau
MAST3 microtubule associated serine/threonine kinase 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MTSS1 metastasis suppressor 1
NUDCD3 NudC domain containing 3
PCDHB6 protocadherin beta 6
PDE4DIP phosphodiesterase 4D interacting protein
PDE9A phosphodiesterase 9A
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRICKLE3 prickle homolog 3 (Drosophila)
PRPH peripherin
RAB29 RAB29, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REEP1 receptor accessory protein 1
RIMS3 regulating synaptic membrane exocytosis 3
S100A8 S100 calcium binding protein A8
SCAI suppressor of cancer cell invasion
SCAPER S-phase cyclin A-associated protein in the ER
SCN1B sodium channel, voltage gated, type I beta subunit
SDC2 syndecan 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFTPB surfactant protein B
SFXN3 sideroflexin 3
SH2B2 SH2B adaptor protein 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SOBP sine oculis binding protein homolog (Drosophila)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
SUGP1 SURP and G patch domain containing 1
SYT17 synaptotagmin XVII
TESC tescalcin
TTC33 tetratricopeptide repeat domain 33
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
USP48 ubiquitin specific peptidase 48
VGF VGF nerve growth factor inducible
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF204P zinc finger protein 204, pseudogene
ZNF821 zinc finger protein 821
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
AEN apoptosis enhancing nuclease
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BFSP1 beaded filament structural protein 1, filensin
BRD9 bromodomain containing 9
C5ORF45 chromosome 5 open reading frame 45
CASD1 CAS1 domain containing 1
CCDC94 coiled-coil domain containing 94
CD3EAP CD3e molecule, epsilon associated protein
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAL4 dynein, axonemal, light chain 4
DTWD1 DTW domain containing 1
ELMO3 engulfment and cell motility 3
EMD emerin
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAAH fatty acid amide hydrolase
FAM192A family with sequence similarity 192, member A
FOSL1 FOS-like antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GDAP1 ganglioside induced differentiation associated protein 1
GPR87 G protein-coupled receptor 87
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP8 GTP-binding protein 8 (putative)
HYAL2 hyaluronoglucosaminidase 2
ING3 inhibitor of growth family, member 3
IRF7 interferon regulatory factor 7
KAT2B K(lysine) acetyltransferase 2B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA0125 KIAA0125
KLF3 Kruppel-like factor 3 (basic)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LINC00339 long intergenic non-protein coding RNA 339
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
LRRC8E leucine rich repeat containing 8 family, member E
LY6G5C lymphocyte antigen 6 complex, locus G5C
LZTFL1 leucine zipper transcription factor-like 1
MAGEF1 melanoma antigen family F1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCM9 minichromosome maintenance complex component 9
MDM4 MDM4, p53 regulator
MED15 mediator complex subunit 15
MORC3 MORC family CW-type zinc finger 3
MPDU1 mannose-P-dolichol utilization defect 1
MSRA methionine sulfoxide reductase A
MTG1 mitochondrial ribosome-associated GTPase 1
MYLIP myosin regulatory light chain interacting protein
NABP2 nucleic acid binding protein 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
PAQR6 progestin and adipoQ receptor family member VI
PC pyruvate carboxylase
PCNT pericentrin
PEX26 peroxisomal biogenesis factor 26
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM14 RNA binding motif protein 14
REEP4 receptor accessory protein 4
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF31 ring finger protein 31
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SECISBP2 SECIS binding protein 2
SLC25A40 solute carrier family 25, member 40
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC41A3 solute carrier family 41, member 3
SPIDR scaffolding protein involved in DNA repair
TCTN1 tectonic family member 1
TGFB3 transforming growth factor, beta 3
THAP1 THAP domain containing, apoptosis associated protein 1
THBS3 thrombospondin 3
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM2 transmembrane protein 2
TPTE transmembrane phosphatase with tensin homology
TSPAN1 tetraspanin 1
TSSC4 tumor suppressing subtransferable candidate 4
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
VEGFC vascular endothelial growth factor C
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR4 WD repeat domain 4
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB3 zinc finger and BTB domain containing 3
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF280D zinc finger protein 280D
ZNF668 zinc finger protein 668
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