vancomycin-2498 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the vancomycin-2498 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGPTL2 angiopoietin-like 2
APC2 adenomatosis polyposis coli 2
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATAT1 alpha tubulin acetyltransferase 1
BARX1 BARX homeobox 1
BBS9 Bardet-Biedl syndrome 9
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CD70 CD70 molecule
CDC14A cell division cycle 14A
CFAP45 cilia and flagella associated protein 45
CNPY4 canopy FGF signaling regulator 4
COL1A2 collagen, type I, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
CTSZ cathepsin Z
DLK2 delta-like 2 homolog (Drosophila)
DSCAM Down syndrome cell adhesion molecule
EDNRA endothelin receptor type A
EFNA4 ephrin-A4
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ESRRA estrogen-related receptor alpha
EXOSC2 exosome component 2
FBXL18 F-box and leucine-rich repeat protein 18
FGFR2 fibroblast growth factor receptor 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLIPR1 GLI pathogenesis-related 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR22 G protein-coupled receptor 22
GPX2 glutathione peroxidase 2
GVINP1 GTPase, very large interferon inducible pseudogene 1
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HOXA4 homeobox A4
IDS iduronate 2-sulfatase
IFNA14 interferon, alpha 14
IHH indian hedgehog
IL2 interleukin 2
ING2 inhibitor of growth family, member 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LEPR leptin receptor
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRC1 leucine rich repeat containing 1
MAP7 microtubule-associated protein 7
MAX MYC associated factor X
MBNL3 muscleblind-like splicing regulator 3
MMP3 matrix metallopeptidase 3
MYL10 myosin, light chain 10, regulatory
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEUROD4 neuronal differentiation 4
NOV nephroblastoma overexpressed
NPPA natriuretic peptide A
NPR1 natriuretic peptide receptor 1
NPTXR neuronal pentraxin receptor
NUP88 nucleoporin 88kDa
PAX5 paired box 5
PDIA2 protein disulfide isomerase family A, member 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHF8 PHD finger protein 8
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PML promyelocytic leukemia
PODNL1 podocan-like 1
POU2F2 POU class 2 homeobox 2
PPARA peroxisome proliferator-activated receptor alpha
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTH1R parathyroid hormone 1 receptor
QPCTL glutaminyl-peptide cyclotransferase-like
RAB26 RAB26, member RAS oncogene family
RANBP1 RAN binding protein 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
REPS1 RALBP1 associated Eps domain containing 1
RFPL3S RFPL3 antisense
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN5A sodium channel, voltage gated, type V alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SH3PXD2A SH3 and PX domains 2A
SHOX2 short stature homeobox 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOX10 SRY (sex determining region Y)-box 10
SRSF7 serine/arginine-rich splicing factor 7
STS steroid sulfatase (microsomal), isozyme S
SURF2 surfeit 2
TCP11L1 t-complex 11, testis-specific-like 1
TNC tenascin C
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TP53I11 tumor protein p53 inducible protein 11
TTLL3 tubulin tyrosine ligase-like family member 3
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VNN1 vanin 1
ZER1 zyg-11 related, cell cycle regulator
ZFHX2 zinc finger homeobox 2
ZNF444 zinc finger protein 444
ZNF550 zinc finger protein 550
ZNF778 zinc finger protein 778
ZSCAN18 zinc finger and SCAN domain containing 18
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACBD4 acyl-CoA binding domain containing 4
ADTRP androgen-dependent TFPI-regulating protein
AIM2 absent in melanoma 2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
BIK BCL2-interacting killer (apoptosis-inducing)
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
C1ORF56 chromosome 1 open reading frame 56
C9ORF9 chromosome 9 open reading frame 9
CBR3 carbonyl reductase 3
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CEND1 cell cycle exit and neuronal differentiation 1
CES3 carboxylesterase 3
CFP complement factor properdin
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN2 chloride channel, voltage-sensitive 2
CNTN1 contactin 1
CTSD cathepsin D
CTSV cathepsin V
DCAF17 DDB1 and CUL4 associated factor 17
DGKG diacylglycerol kinase, gamma 90kDa
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
FGL1 fibrinogen-like 1
FLJ21369 uncharacterized protein FLJ21369
FLRT1 fibronectin leucine rich transmembrane protein 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FZD3 frizzled class receptor 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GPR1 G protein-coupled receptor 1
GRIP2 glutamate receptor interacting protein 2
HIST1H2AJ histone cluster 1, H2aj
HSPB8 heat shock 22kDa protein 8
IFT46 intraflagellar transport 46
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KIAA1107 KIAA1107
LATS1 large tumor suppressor kinase 1
LRP2 low density lipoprotein receptor-related protein 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGIX MAGI family member, X-linked
MAK male germ cell-associated kinase
MEGF8 multiple EGF-like-domains 8
METRN meteorin, glial cell differentiation regulator
METTL8 methyltransferase like 8
MPDU1 mannose-P-dolichol utilization defect 1
MTRF1 mitochondrial translational release factor 1
NCKAP1L NCK-associated protein 1-like
NECAB2 N-terminal EF-hand calcium binding protein 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NLK nemo-like kinase
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI2 peptidyl arginine deiminase, type II
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLCD1 phospholipase C, delta 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPT2 palmitoyl-protein thioesterase 2
PQLC2 PQ loop repeat containing 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB3A RAB3A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SH3BGR SH3 domain binding glutamate-rich protein
SLFN12 schlafen family member 12
SOX12 SRY (sex determining region Y)-box 12
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAT5A signal transducer and activator of transcription 5A
TAOK1 TAO kinase 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS4 thrombospondin 4
TMEM140 transmembrane protein 140
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D4 TSC22 domain family, member 4
USP19 ubiquitin specific peptidase 19
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
VWA1 von Willebrand factor A domain containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZNF254 zinc finger protein 254
ZNF34 zinc finger protein 34
ZNF442 zinc finger protein 442
ZNF862 zinc finger protein 862