vancomycin-2858 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the vancomycin-2858 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AGMAT agmatine ureohydrolase (agmatinase)
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATN1 atrophin 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BTF3P12 basic transcription factor 3 pseudogene 12
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCDC9 coiled-coil domain containing 9
CD52 CD52 molecule
CD82 CD82 molecule
CFAP45 cilia and flagella associated protein 45
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLEC2B C-type lectin domain family 2, member B
DGKG diacylglycerol kinase, gamma 90kDa
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
EIF1 eukaryotic translation initiation factor 1
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
EN1 engrailed homeobox 1
FBLN1 fibulin 1
FFAR2 free fatty acid receptor 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ11292
FYB FYN binding protein
GAS7 growth arrest-specific 7
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GK glycerol kinase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPC3 glypican 3
GRM8 glutamate receptor, metabotropic 8
GRPR gastrin-releasing peptide receptor
H2AFX H2A histone family, member X
HCRP1 hepatocellular carcinoma-related HCRP1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIPK2 homeodomain interacting protein kinase 2
HIST1H4F histone cluster 1, H4f
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IL1B interleukin 1, beta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL6ST interleukin 6 signal transducer
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGB5 integrin, beta 5
KCNIP1 Kv channel interacting protein 1
LAX1 lymphocyte transmembrane adaptor 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRP2 low density lipoprotein receptor-related protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MEX3D mex-3 RNA binding family member D
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NDRG2 NDRG family member 2
NEUROD4 neuronal differentiation 4
NPAS2 neuronal PAS domain protein 2
PDCD6 programmed cell death 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC4 placenta-specific 4
PLIN2 perilipin 2
PRB1 proline-rich protein BstNI subfamily 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RHAG Rh-associated glycoprotein
RNF39 ring finger protein 39
RNFT1 ring finger protein, transmembrane 1
SCAI suppressor of cancer cell invasion
SCN10A sodium channel, voltage gated, type X alpha subunit
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIDT2 SID1 transmembrane family, member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SORBS3 sorbin and SH3 domain containing 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STXBP5L syntaxin binding protein 5-like
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCP10 t-complex 10
TEP1 telomerase-associated protein 1
TLR2 toll-like receptor 2
TM4SF1 transmembrane 4 L six family member 1
TMEM53 transmembrane protein 53
TMEM8B transmembrane protein 8B
TRBC1 T cell receptor beta constant 1
TRIB2 tribbles pseudokinase 2
TRIM29 tripartite motif containing 29
TRIM33 tripartite motif containing 33
TUBA3C tubulin, alpha 3c
USP36 ubiquitin specific peptidase 36
VEGFA vascular endothelial growth factor A
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF222 zinc finger protein 222
ZNF287 zinc finger protein 287
ZNF419 zinc finger protein 419
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRE5 adhesion G protein-coupled receptor E5
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX15 arachidonate 15-lipoxygenase
ANXA2P3 annexin A2 pseudogene 3
ATG2B autophagy related 2B
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCOR BCL6 corepressor
C1ORF106 chromosome 1 open reading frame 106
C1ORF159 chromosome 1 open reading frame 159
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC88C coiled-coil domain containing 88C
CHML choroideremia-like (Rab escort protein 2)
CLDN15 claudin 15
CLGN calmegin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXORF56 chromosome X open reading frame 56
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
EFCAB2 EF-hand calcium binding domain 2
FAM204A family with sequence similarity 204, member A
FBXW12 F-box and WD repeat domain containing 12
FCHSD2 FCH and double SH3 domains 2
FGGY FGGY carbohydrate kinase domain containing
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAS8 growth arrest-specific 8
GLB1L2 galactosidase, beta 1-like 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HIST1H2AI histone cluster 1, H2ai
HIST1H2BO histone cluster 1, H2bo
HOXA4 homeobox A4
IDI2-AS1 IDI2 antisense RNA 1
IRF2 interferon regulatory factor 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
KLHL26 kelch-like family member 26
KLK5 kallikrein-related peptidase 5
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5 low density lipoprotein receptor-related protein 5
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBNL3 muscleblind-like splicing regulator 3
MDM4 MDM4, p53 regulator
MRPL41 mitochondrial ribosomal protein L41
MT1H metallothionein 1H
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NIPAL2 NIPA-like domain containing 2
NLRX1 NLR family member X1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGFRL1 opioid growth factor receptor-like 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PCNXL4 pecanex-like 4 (Drosophila)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PITX2 paired-like homeodomain 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POLL polymerase (DNA directed), lambda
RAB33B RAB33B, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM41 RNA binding motif protein 41
RHOH ras homolog family member H
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL23AP32 ribosomal protein L23a pseudogene 32
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCRN3 secernin 3
SLC12A8 solute carrier family 12, member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SRPX sushi-repeat containing protein, X-linked
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
SYBU syntabulin (syntaxin-interacting)
SYT17 synaptotagmin XVII
TM7SF3 transmembrane 7 superfamily member 3
TMEM120B transmembrane protein 120B
TMEM242 transmembrane protein 242
TNK1 tyrosine kinase, non-receptor, 1
TNS2 tensin 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
VEGFC vascular endothelial growth factor C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFP30 ZFP30 zinc finger protein
ZFP36 ZFP36 ring finger protein
ZNF16 zinc finger protein 16
ZNF329 zinc finger protein 329
ZNF571 zinc finger protein 571
ZNF623 zinc finger protein 623
ZNF639 zinc finger protein 639
ZNF816 zinc finger protein 816