| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the vancomycin-4598 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADD2 | adducin 2 (beta) |
| AK5 | adenylate kinase 5 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATN1 | atrophin 1 |
| ATP10A | ATPase, class V, type 10A |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPN9 | calpain 9 |
| CBX2 | chromobox homolog 2 |
| CCDC40 | coiled-coil domain containing 40 |
| CCDC64 | coiled-coil domain containing 64 |
| CCDC85B | coiled-coil domain containing 85B |
| CDC14A | cell division cycle 14A |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHN2 | chimerin 2 |
| COL2A1 | collagen, type II, alpha 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CREM | cAMP responsive element modulator |
| CRISP2 | cysteine-rich secretory protein 2 |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CTSS | cathepsin S |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXC5 | homeobox C5 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL12A | interleukin 12A |
| IZUMO4 | IZUMO family member 4 |
| JRK | Jrk homolog (mouse) |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL22 | kelch-like family member 22 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LMNA | lamin A/C |
| LRRK1 | leucine-rich repeat kinase 1 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MEGF6 | multiple EGF-like-domains 6 |
| MINK1 | misshapen-like kinase 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MYRF | myelin regulatory factor |
| NCALD | neurocalcin delta |
| NFIB | nuclear factor I/B |
| NPPB | natriuretic peptide B |
| NPR2 | natriuretic peptide receptor 2 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUDC | nudC nuclear distribution protein |
| NUP54 | nucleoporin 54kDa |
| PASK | PAS domain containing serine/threonine kinase |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDS5A | PDS5 cohesin associated factor A |
| PGP | phosphoglycolate phosphatase |
| PHF20 | PHD finger protein 20 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RUNX1 | runt-related transcription factor 1 |
| RXRB | retinoid X receptor, beta |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TBX6 | T-box 6 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TFEB | transcription factor EB |
| TLN2 | talin 2 |
| VCL | vinculin |
| VEGFA | vascular endothelial growth factor A |
| WDR59 | WD repeat domain 59 |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF219 | zinc finger protein 219 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARL15 | ADP-ribosylation factor-like 15 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CD68 | CD68 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CEL | carboxyl ester lipase |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNN1 | calponin 1, basic, smooth muscle |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CPZ | carboxypeptidase Z |
| CSF1R | colony stimulating factor 1 receptor |
| CST1 | cystatin SN |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DAGLA | diacylglycerol lipase, alpha |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DENND2D | DENN/MADD domain containing 2D |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| FAM184A | family with sequence similarity 184, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXO2 | F-box protein 2 |
| FGF23 | fibroblast growth factor 23 |
| FZD10 | frizzled class receptor 10 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H4A | histone cluster 1, H4a |
| IFNA14 | interferon, alpha 14 |
| IL17RB | interleukin 17 receptor B |
| INCENP | inner centromere protein antigens 135/155kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIFC3 | kinesin family member C3 |
| KLHL25 | kelch-like family member 25 |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LOC257152 | uncharacterized LOC257152 |
| LYRM9 | LYR motif containing 9 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDM4 | MDM4, p53 regulator |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MUC7 | mucin 7, secreted |
| NAG18 | NAG18 mRNA |
| NDE1 | nudE neurodevelopment protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OSMR | oncostatin M receptor |
| PADI1 | peptidyl arginine deiminase, type I |
| PCBP4 | poly(rC) binding protein 4 |
| PLAC8 | placenta-specific 8 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGRIP1L | RPGRIP1-like |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SND1-IT1 | SND1 intronic transcript 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| TWISTNB | TWIST neighbor |
| VGLL3 | vestigial-like family member 3 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF214 | zinc finger protein 214 |
| ZNF254 | zinc finger protein 254 |
| ZNF286A | zinc finger protein 286A |
| ZNF343 | zinc finger protein 343 |
| ZNF415 | zinc finger protein 415 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF747 | zinc finger protein 747 |