vancomycin-4598 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the vancomycin-4598 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAM2 ADAM metallopeptidase domain 2
ADD2 adducin 2 (beta)
AK5 adenylate kinase 5
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGAP28 Rho GTPase activating protein 28
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATN1 atrophin 1
ATP10A ATPase, class V, type 10A
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF29 chromosome 22 open reading frame 29
C2ORF72 chromosome 2 open reading frame 72
CAMKMT calmodulin-lysine N-methyltransferase
CAPN9 calpain 9
CBX2 chromobox homolog 2
CCDC40 coiled-coil domain containing 40
CCDC64 coiled-coil domain containing 64
CCDC85B coiled-coil domain containing 85B
CDC14A cell division cycle 14A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN2 chimerin 2
COL2A1 collagen, type II, alpha 1
CREB5 cAMP responsive element binding protein 5
CREM cAMP responsive element modulator
CRISP2 cysteine-rich secretory protein 2
CSPG4 chondroitin sulfate proteoglycan 4
CTSS cathepsin S
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLJ11710 uncharacterized protein FLJ11710
FUBP1 far upstream element (FUSE) binding protein 1
GREM1 gremlin 1, DAN family BMP antagonist
GRWD1 glutamate-rich WD repeat containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AK histone cluster 1, H2ak
HOXC5 homeobox C5
ICOSLG inducible T-cell co-stimulator ligand
IL12A interleukin 12A
IZUMO4 IZUMO family member 4
JRK Jrk homolog (mouse)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF4 Kruppel-like factor 4 (gut)
KLHL22 kelch-like family member 22
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LGALS8 lectin, galactoside-binding, soluble, 8
LMNA lamin A/C
LRRK1 leucine-rich repeat kinase 1
LRRN2 leucine rich repeat neuronal 2
MEGF6 multiple EGF-like-domains 6
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MYRF myelin regulatory factor
NCALD neurocalcin delta
NFIB nuclear factor I/B
NPPB natriuretic peptide B
NPR2 natriuretic peptide receptor 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NUDC nudC nuclear distribution protein
NUP54 nucleoporin 54kDa
PASK PAS domain containing serine/threonine kinase
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDS5A PDS5 cohesin associated factor A
PGP phosphoglycolate phosphatase
PHF20 PHD finger protein 20
POFUT1 protein O-fucosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
RABGAP1L RAB GTPase activating protein 1-like
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REPS1 RALBP1 associated Eps domain containing 1
RGS5 regulator of G-protein signaling 5
RUNX1 runt-related transcription factor 1
RXRB retinoid X receptor, beta
SAYSD1 SAYSVFN motif domain containing 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOGA1 suppressor of glucose, autophagy associated 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBX6 T-box 6
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFEB transcription factor EB
TLN2 talin 2
VCL vinculin
VEGFA vascular endothelial growth factor A
WDR59 WD repeat domain 59
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
WSB1 WD repeat and SOCS box containing 1
ZCCHC11 zinc finger, CCHC domain containing 11
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP64 ZFP64 zinc finger protein
ZNF219 zinc finger protein 219
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSL5 acyl-CoA synthetase long-chain family member 5
AKAP5 A kinase (PRKA) anchor protein 5
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C17ORF53 chromosome 17 open reading frame 53
C1ORF56 chromosome 1 open reading frame 56
C22ORF46 chromosome 22 open reading frame 46
CD68 CD68 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CEL carboxyl ester lipase
CIDEB cell death-inducing DFFA-like effector b
CNN1 calponin 1, basic, smooth muscle
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPZ carboxypeptidase Z
CSF1R colony stimulating factor 1 receptor
CST1 cystatin SN
CXCR2 chemokine (C-X-C motif) receptor 2
DAGLA diacylglycerol lipase, alpha
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DENND2D DENN/MADD domain containing 2D
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FAM184A family with sequence similarity 184, member A
FAM63A family with sequence similarity 63, member A
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
FZD10 frizzled class receptor 10
GAL3ST4 galactose-3-O-sulfotransferase 4
GJA8 gap junction protein, alpha 8, 50kDa
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GSTCD glutathione S-transferase, C-terminal domain containing
HAMP hepcidin antimicrobial peptide
HIST1H1T histone cluster 1, H1t
HIST1H4A histone cluster 1, H4a
IFNA14 interferon, alpha 14
IL17RB interleukin 17 receptor B
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIFC3 kinesin family member C3
KLHL25 kelch-like family member 25
LINC00472 long intergenic non-protein coding RNA 472
LOC257152 uncharacterized LOC257152
LYRM9 LYR motif containing 9
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MN1 meningioma (disrupted in balanced translocation) 1
MNMIP1 manchette microtubule inner protein 1
MUC7 mucin 7, secreted
NAG18 NAG18 mRNA
NDE1 nudE neurodevelopment protein 1
NEUROD4 neuronal differentiation 4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSMR oncostatin M receptor
PADI1 peptidyl arginine deiminase, type I
PCBP4 poly(rC) binding protein 4
PLAC8 placenta-specific 8
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RPGRIP1L RPGRIP1-like
SAMD9 sterile alpha motif domain containing 9
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SGK2 serum/glucocorticoid regulated kinase 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMR3A submaxillary gland androgen regulated protein 3A
SND1-IT1 SND1 intronic transcript 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
TWISTNB TWIST neighbor
VGLL3 vestigial-like family member 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF214 zinc finger protein 214
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF343 zinc finger protein 343
ZNF415 zinc finger protein 415
ZNF702P zinc finger protein 702, pseudogene
ZNF747 zinc finger protein 747