vandetanib Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	A quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. (Chemical Entities of Biological Interest Ontology, CHEBI_49960)
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Genes

8 genes co-occuring with the biological term vandetanib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
CXCR4	chemokine (C-X-C motif) receptor 4
EGF	epidermal growth factor
EGFR	epidermal growth factor receptor
KDR	kinase insert domain receptor
MMP14	matrix metallopeptidase 14 (membrane-inserted)
PTEN	phosphatase and tensin homolog
VEGFA	vascular endothelial growth factor A