vanoxerine-1625 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the vanoxerine-1625 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACOT11 acyl-CoA thioesterase 11
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
APH1B APH1B gamma secretase subunit
ATF7IP2 activating transcription factor 7 interacting protein 2
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BICD1 bicaudal D homolog 1 (Drosophila)
C22ORF29 chromosome 22 open reading frame 29
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN10 calpain 10
CCL2 chemokine (C-C motif) ligand 2
CD44 CD44 molecule (Indian blood group)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CIZ1 CDKN1A interacting zinc finger protein 1
CKB creatine kinase, brain
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CYB561 cytochrome b561
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDR1 discoidin domain receptor tyrosine kinase 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR2 DiGeorge syndrome critical region gene 2
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DUS2 dihydrouridine synthase 2
EDC3 enhancer of mRNA decapping 3
EIF3L eukaryotic translation initiation factor 3, subunit L
EMC1 ER membrane protein complex subunit 1
EMD emerin
FASTK Fas-activated serine/threonine kinase
GAB2 GRB2-associated binding protein 2
GATA2 GATA binding protein 2
GHRHR growth hormone releasing hormone receptor
GOLGA4 golgin A4
GRK6 G protein-coupled receptor kinase 6
IGFLR1 IGF-like family receptor 1
IMPAD1 inositol monophosphatase domain containing 1
KIF23 kinesin family member 23
KIZ kizuna centrosomal protein
LMNA lamin A/C
LRRC37A2 leucine rich repeat containing 37, member A2
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAP4 microtubule-associated protein 4
MBNL2 muscleblind-like splicing regulator 2
MTRF1L mitochondrial translational release factor 1-like
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NACA nascent polypeptide-associated complex alpha subunit
NDE1 nudE neurodevelopment protein 1
NDRG2 NDRG family member 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOS1 nitric oxide synthase 1 (neuronal)
NPTXR neuronal pentraxin receptor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCM1 pericentriolar material 1
PDCL phosducin-like
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLAC1 placenta-specific 1
PLCB2 phospholipase C, beta 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPP1R10 protein phosphatase 1, regulatory subunit 10
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RANBP9 RAN binding protein 9
RECQL4 RecQ protein-like 4
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RRBP1 ribosome binding protein 1
RTEL1 regulator of telomere elongation helicase 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SETD4 SET domain containing 4
SIRAL2 SIR2 antiphage like 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SMAD3 SMAD family member 3
SNX11 sorting nexin 11
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPN sialophorin
SRPR signal recognition particle receptor (docking protein)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYNJ2 synaptojanin 2
TBL1X transducin (beta)-like 1X-linked
THTPA thiamine triphosphatase
TK2 thymidine kinase 2, mitochondrial
TM9SF4 transmembrane 9 superfamily protein member 4
TRAF1 TNF receptor-associated factor 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC22D3 TSC22 domain family, member 3
TTC31 tetratricopeptide repeat domain 31
UNC45A unc-45 homolog A (C. elegans)
UQCRB ubiquinol-cytochrome c reductase binding protein
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZMYND8 zinc finger, MYND-type containing 8
ZNF408 zinc finger protein 408
ZNF512B zinc finger protein 512B
ZNF710 zinc finger protein 710
ZNHIT1 zinc finger, HIT-type containing 1

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADGRA3 adhesion G protein-coupled receptor A3
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
APOBR apolipoprotein B receptor
C14ORF159 chromosome 14 open reading frame 159
C19ORF24 chromosome 19 open reading frame 24
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC47 coiled-coil domain containing 47
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC25B cell division cycle 25B
CDC7 cell division cycle 7
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CISH cytokine inducible SH2-containing protein
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
COMMD10 COMM domain containing 10
CORO2A coronin, actin binding protein, 2A
CRIPT cysteine-rich PDZ-binding protein
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DEXI Dexi homolog (mouse)
DMXL1 Dmx-like 1
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DPP3 dipeptidyl-peptidase 3
DSN1 DSN1, MIS12 kinetochore complex component
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ELMO1 engulfment and cell motility 1
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ERCC2 excision repair cross-complementation group 2
ERMP1 endoplasmic reticulum metallopeptidase 1
FBXL4 F-box and leucine-rich repeat protein 4
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GPATCH2 G patch domain containing 2
HARS histidyl-tRNA synthetase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL4R interleukin 4 receptor
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
KCTD15 potassium channel tetramerization domain containing 15
KCTD5 potassium channel tetramerization domain containing 5
KIAA1551 KIAA1551
LBR lamin B receptor
LOC642236 FSHD region gene 1 pseudogene
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAN2B2 mannosidase, alpha, class 2B, member 2
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAVS mitochondrial antiviral signaling protein
MICB MHC class I polypeptide-related sequence B
MSL2 male-specific lethal 2 homolog (Drosophila)
MT1HL1 metallothionein 1H-like 1
MTG1 mitochondrial ribosome-associated GTPase 1
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NCKAP1L NCK-associated protein 1-like
NUBP1 nucleotide binding protein 1
NUPL1 nucleoporin like 1
OPN3 opsin 3
ORC1 origin recognition complex, subunit 1
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAK1IP1 PAK1 interacting protein 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLAG1 pleiomorphic adenoma gene 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRPF3 pre-mRNA processing factor 3
PTCD1 pentatricopeptide repeat domain 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTOV1 prostate tumor overexpressed 1
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RBM47 RNA binding motif protein 47
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RRP1 ribosomal RNA processing 1
S100A9 S100 calcium binding protein A9
SAC3D1 SAC3 domain containing 1
SASH3 SAM and SH3 domain containing 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TESK2 testis-specific kinase 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM14A transmembrane protein 14A
TRIM28 tripartite motif containing 28
TSC1 tuberous sclerosis 1
TSC22D1 TSC22 domain family, member 1
TSPAN14 tetraspanin 14
TUBA3D tubulin, alpha 3d
TXLNA taxilin alpha
USB1 U6 snRNA biogenesis 1
USP8 ubiquitin specific peptidase 8
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YEATS4 YEATS domain containing 4
YIPF3 Yip1 domain family, member 3
ZNF91 zinc finger protein 91
ZSCAN9 zinc finger and SCAN domain containing 9