vanoxerine-3240 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the vanoxerine-3240 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AREG amphiregulin
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF66 chromosome 19 open reading frame 66
CD58 CD58 molecule
CDK6 cyclin-dependent kinase 6
CDKL3 cyclin-dependent kinase-like 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLEC4A C-type lectin domain family 4, member A
COL4A1 collagen, type IV, alpha 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DMXL2 Dmx-like 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EGR1 early growth response 1
EGR3 early growth response 3
EPHB2 EPH receptor B2
FGB fibrinogen beta chain
FGFR1 fibroblast growth factor receptor 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXI1 forkhead box I1
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLRA2 glycine receptor, alpha 2
GMPR guanosine monophosphate reductase
GRIK2 glutamate receptor, ionotropic, kainate 2
GRM1 glutamate receptor, metabotropic 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEXA-AS1 HEXA antisense RNA 1
HIST1H2BG histone cluster 1, H2bg
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST2H2BE histone cluster 2, H2be
HPCAL4 hippocalcin like 4
IER2 immediate early response 2
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT54 intraflagellar transport 54
INHBE inhibin, beta E
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KIF1C kinesin family member 1C
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMX1B LIM homeobox transcription factor 1, beta
LOC157562 uncharacterized LOC157562
LOC51145 uncharacterized LOC51145
LRP12 low density lipoprotein receptor-related protein 12
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2 microtubule-associated protein 2
MEGF8 multiple EGF-like-domains 8
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NPR1 natriuretic peptide receptor 1
NPVF neuropeptide VF precursor
NRG2 neuregulin 2
OASL 2'-5'-oligoadenylate synthetase-like
OVGP1 oviductal glycoprotein 1, 120kDa
PDE4DIP phosphodiesterase 4D interacting protein
PHEX phosphate regulating endopeptidase homolog, X-linked
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTCRA pre T-cell antigen receptor alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RARA retinoic acid receptor, alpha
RETN resistin
RND1 Rho family GTPase 1
SCAND2P SCAN domain containing 2 pseudogene
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A4 solute carrier family 16, member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SPARCL1 SPARC-like 1 (hevin)
SPRY2 sprouty homolog 2 (Drosophila)
THAP3 THAP domain containing, apoptosis associated protein 3
TMPRSS4 transmembrane protease, serine 4
TRIM10 tripartite motif containing 10
VEGFA vascular endothelial growth factor A
WAS Wiskott-Aldrich syndrome
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZFP36 ZFP36 ring finger protein
ZNF44 zinc finger protein 44
ZNF646 zinc finger protein 646
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
ATP7B ATPase, Cu++ transporting, beta polypeptide
BMP4 bone morphogenetic protein 4
C14ORF79 chromosome 14 open reading frame 79
C1ORF115 chromosome 1 open reading frame 115
C2ORF44 chromosome 2 open reading frame 44
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD82 CD82 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CHML choroideremia-like (Rab escort protein 2)
CNGB3 cyclic nucleotide gated channel beta 3
COL4A5 collagen, type IV, alpha 5
COL9A2 collagen, type IX, alpha 2
CRYGC crystallin, gamma C
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
EML4 echinoderm microtubule associated protein like 4
F8 coagulation factor VIII, procoagulant component
FAM131A family with sequence similarity 131, member A
FAM186A family with sequence similarity 186, member A
FKBP10 FK506 binding protein 10, 65 kDa
FMO4 flavin containing monooxygenase 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GEMIN8 gem (nuclear organelle) associated protein 8
GIF gastric intrinsic factor (vitamin B synthesis)
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GSTA4 glutathione S-transferase alpha 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXC5 homeobox C5
IDI2-AS1 IDI2 antisense RNA 1
IPO8 importin 8
ITGA10 integrin, alpha 10
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM8 lysine (K)-specific demethylase 8
KLHL28 kelch-like family member 28
LMNB1 lamin B1
LRP2 low density lipoprotein receptor-related protein 2
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCC mutated in colorectal cancers
MED9 mediator complex subunit 9
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
MYO1E myosin IE
NLRX1 NLR family member X1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAIP2B poly(A) binding protein interacting protein 2B
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB8 protocadherin beta 8
PCDHGB5 protocadherin gamma subfamily B, 5
PER3 period circadian clock 3
PHC3 polyhomeotic homolog 3 (Drosophila)
POLL polymerase (DNA directed), lambda
RAB23 RAB23, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFTN1 raftlin, lipid raft linker 1
RIN1 Ras and Rab interactor 1
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RUNDC3B RUN domain containing 3B
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
STAB2 stabilin 2
STON1 stonin 1
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNC syncoilin, intermediate filament protein
TCTA T-cell leukemia translocation altered
TDRD1 tudor domain containing 1
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP3 transcription factor Dp family, member 3
THBS3 thrombospondin 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMEM180 transmembrane protein 180
TRIM21 tripartite motif containing 21
USP19 ubiquitin specific peptidase 19
VEGFC vascular endothelial growth factor C
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26