vanoxerine-4641 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the vanoxerine-4641 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
AKR1C2 aldo-keto reductase family 1, member C2
ANGEL2 angel homolog 2 (Drosophila)
ANGPTL4 angiopoietin-like 4
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL14 ADP-ribosylation factor-like 14
ARSA arylsulfatase A
ASB1 ankyrin repeat and SOCS box containing 1
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
BRD2 bromodomain containing 2
C1ORF116 chromosome 1 open reading frame 116
CDC14A cell division cycle 14A
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPEB3 cytoplasmic polyadenylation element binding protein 3
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
DCAF11 DDB1 and CUL4 associated factor 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ETV6 ets variant 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM46A family with sequence similarity 46, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45B growth arrest and DNA-damage-inducible, beta
GAS1 growth arrest-specific 1
GREM1 gremlin 1, DAN family BMP antagonist
GSPT1 G1 to S phase transition 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H3B histone cluster 1, H3b
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFT54 intraflagellar transport 54
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL6 interleukin 6
JAK2 Janus kinase 2
JUN jun proto-oncogene
KDM6A lysine (K)-specific demethylase 6A
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KRT17 keratin 17, type I
LOC284244 uncharacterized LOC284244
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
MT1X metallothionein 1X
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NF1 neurofibromin 1
NFIL3 nuclear factor, interleukin 3 regulated
NOL4 nucleolar protein 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
PBOV1 prostate and breast cancer overexpressed 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RND1 Rho family GTPase 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNX1 runt-related transcription factor 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
STOML1 stomatin (EPB72)-like 1
SVIL supervillin
TAPBP TAP binding protein (tapasin)
WSB1 WD repeat and SOCS box containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF467 zinc finger protein 467
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ALB albumin
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANOS1 anosmin 1
ARPIN actin-related protein 2/3 complex inhibitor
ASTN1 astrotactin 1
BAG4 BCL2-associated athanogene 4
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C5ORF45 chromosome 5 open reading frame 45
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CD72 CD72 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CGA glycoprotein hormones, alpha polypeptide
CIDEB cell death-inducing DFFA-like effector b
CNGB3 cyclic nucleotide gated channel beta 3
CSF1R colony stimulating factor 1 receptor
DAGLA diacylglycerol lipase, alpha
DDN dendrin
EHF ets homologous factor
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FAM131B family with sequence similarity 131, member B
FGF6 fibroblast growth factor 6
FLJ21369 uncharacterized protein FLJ21369
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GMPR guanosine monophosphate reductase
GSTA3 glutathione S-transferase alpha 3
HPR haptoglobin-related protein
ICOS inducible T-cell co-stimulator
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KRT33A keratin 33A, type I
KRT8P12 keratin 8 pseudogene 12
KRTAP1-3 keratin associated protein 1-3
LAMC3 laminin, gamma 3
LBX1 ladybird homeobox 1
LIG4 ligase IV, DNA, ATP-dependent
LINC00597 long intergenic non-protein coding RNA 597
LOC100129648 uncharacterized LOC100129648
LOC100272216 uncharacterized LOC100272216
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MBTD1 mbt domain containing 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD12 major facilitator superfamily domain containing 12
MTA2 metastasis associated 1 family, member 2
MYH15 myosin, heavy chain 15
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEUROD4 neuronal differentiation 4
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRN1 neuritin 1
NT5M 5',3'-nucleotidase, mitochondrial
NTF3 neurotrophin 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSMR oncostatin M receptor
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB13 protocadherin beta 13
PDE12 phosphodiesterase 12
PDE8B phosphodiesterase 8B
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRB3 proline-rich protein BstNI subfamily 3
PRM2 protamine 2
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTTG2 pituitary tumor-transforming 2
RABL6 RAB, member RAS oncogene family-like 6
RGR retinal G protein coupled receptor
RIBC2 RIB43A domain with coiled-coils 2
RIMBP2 RIMS binding protein 2
RNF39 ring finger protein 39
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SFRP5 secreted frizzled-related protein 5
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLN sarcolipin
SREK1IP1 SREK1-interacting protein 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR3 transforming growth factor, beta receptor III
THRAP3 thyroid hormone receptor associated protein 3
TRAPPC13 trafficking protein particle complex 13
TSPAN2 tetraspanin 2
WDR91 WD repeat domain 91
ZNF137P zinc finger protein 137, pseudogene
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF442 zinc finger protein 442
ZNF529 zinc finger protein 529
ZNF770 zinc finger protein 770